John Spudich, Ph.D., Center Director
Structure and function of photoactive membrane receptors and signal transduction triggered by light; rhodopsins and related heptahelical receptors.
Peter Christie, Ph.D.
Macromolecular transport across prokaryotic and eukaryotic membranes; bacterial pathogenicity.
Carmen Dessauer, Ph.D.
G protein mediated signal transduction; regulation of adenylyl cyclase and production of cyclic AMP; regulators of G protein signaling (RGS proteins)
William Dowhan, Ph.D.
Structure, function and assembly of cell membranes; lipid-assisted protein folding.
Alemayehu Gorfe, Ph.D.
Use of computer simulations to study the organization of cell signaling components, interfacial interactions and allostery to aid in the development of treatments for unsolved health challenges
Vasanthi Jayaraman, Ph.D., Center Co-Director
Structure and function of ligand gated ion channels; spectroscopic investigations of membrane proteins.
John Putkey, Ph.D.
Structural and molecular biology of calcium-signaling mechanisms including cardiac muscle contraction, Ca2+ channels, and calmodulin and regulators of calmodulin signaling.
Irina Serysheva, Ph.D.
Structure and function of integral membrane protein complexes; structural basis of ion transport across cell membranes; calcium channels.
Lei Zheng, Ph.D.
Structural biology of membrane proteins; ion transport and regulation; X-ray Crystallography.