- John Spudich, Ph.D., Center Director
Structure and function of photoactive membrane receptors and signal transduction triggered by light; rhodopsins and related heptahelical receptors.
- Peter Christie, Ph.D.
Macromolecular transport across prokaryotic and eukaryotic membranes; bacterial pathogenicity.
- Carmen Dessauer, Ph.D.
G protein mediated signal transduction; regulation of adenylyl cyclase and production of cyclic AMP; regulators of G protein signaling (RGS proteins); relaxin.
- William Dowhan, Ph.D.
Structure, function and assembly of cell membranes; lipid-assisted protein folding.
- Alemayehu Gorfe, Ph.D.
Use of computer simulations to study the organization of cell signaling components, interfacial interactions and allostery to aid in the development of treatments for unsolved health challenges
- John Hancock, M.B., B.Chair, Ph.D.
Plasma membrane nanostructure and signal transduction
- Vasanthi Jayaraman, Ph.D.
Structure and function of ligand gated ion channels; spectroscopic investigations of membrane proteins.
- Ilya Levental, Ph.D.
Membrane structure and post-translational lipidation
- John Putkey, Ph.D.
Structural and molecular biology of calcium-signaling mechanisms including cardiac muscle contraction, Ca2+ channels, and calmodulin and regulators of calmodulin signaling.
- Irina Serysheva, Ph.D.
Structure and function of integral membrane protein complexes; structural basis of ion transport across cell membranes; calcium channels.
- Lei Zheng, Ph.D.
Structural biology of membrane proteins; ion transport and regulation; X-ray Crystallography.