Pathway Comparison – Page Three

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Order Broad Pathway Pathway description Unique id Annotations Description Clone GB acc UG cluster Gene symbol Defined gene lists Parametric p-value Geometric mean of ratios (class Disease /class Normal )
1162 ST_G_alpha_i_Pathway__h Signalling Transduction KE H001717_01 Info RAP1, GTPase activating protein 1 H001717_01 M64788 75151 RAP1GA1 0.0888214 1.197
1163 ST_G_alpha_i_Pathway__h Signalling Transduction KE H001748_01 Info Inositol 1,4,5-trisphosphate 3-kinase B H001748_01 X57206 78877 ITPKB Inositol phosphate metabolism, Phosphatidylinositol signaling system, cell_signaling, signal_transduction 0.1283627 0.851
1164 ST_G_alpha_i_Pathway__h Signalling Transduction KE H001718_01 Info Inositol 1,4,5-trisphosphate 3-kinase A H001718_01 X54938 2722 ITPKA Inositol phosphate metabolism, Phosphatidylinositol signaling system 0.1331494 1.16
1165 ST_G_alpha_i_Pathway__h Signalling Transduction KE H002097_01 Info Dopamine receptor D2 H002097_01 X51362 73893 DRD2 behavior, immunology 0.1531006 0.865
1166 ST_G_alpha_i_Pathway__h Signalling Transduction KE H002346_01 Info Phospholipase C, beta 2 H002346_01 M95678 994 PLCB2 Inositol phosphate metabolism, Phosphatidylinositol signaling system 0.158235 1.161
1167 ST_G_alpha_i_Pathway__h Signalling Transduction KE H009013_01 Info Dopamine receptor D2 H009013_01 AF176812 73893 DRD2 behavior, immunology 0.2238033 1.119
1168 ST_G_alpha_i_Pathway__h Signalling Transduction KE H002943_01 Info V-raf murine sarcoma viral oncogene homolog B1 H002943_01 M95712 622 BRAF MAP Kinase Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction, tsonc 0.2376595 0.895
1169 ST_G_alpha_i_Pathway__h Signalling Transduction KE H003497_01 Info V-akt murine thymoma viral oncogene homolog 2 H003497_01 M77198 326445 AKT2 Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction, tsonc 0.3314111 0.872
1170 ST_G_alpha_i_Pathway__h Signalling Transduction KE H003337_01 Info B-factor, properdin H003337_01 L15702 69771 BF Perou’s – Intrinsi c- Breast-Cancer-Genes, immunology 0.3702495 1.093
1171 ST_G_alpha_i_Pathway__h Signalling Transduction KE H000897_01 Info Inositol 1,4,5-triphosphate receptor, type 2 H000897_01 D26350 238272 ITPR2 0.5011337 1.061
1172 ST_G_alpha_i_Pathway__h Signalling Transduction KE H003612_01 Info V-akt murine thymoma viral oncogene homolog 1 H003612_01 M63167 71816 AKT1 Actions of Nitric Oxide in the Heart, AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, B Cell Survival Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia and p53 in the Cardiovascular system, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, mTOR Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Phospholipase C Signaling Pathway, Phospholipids as signaling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Ras Signaling Pathway, Regulation … 0.6741257 1.038
1173 ST_G_alpha_i_Pathway__h Signalling Transduction KE H003651_01 Info EphB2 H003651_01 AF025304 125124 EPHB2 development 0.7855294 0.971
1174 ST_G_alpha_i_Pathway__h Signalling Transduction KE H007337_01 Info Inositol 1,4,5-triphosphate receptor, type 3 H007337_01 U01062 77515 ITPR3 0.8999809 0.984
1175 ST_G_alpha_i_Pathway__h Signalling Transduction KE H014981_01 Info Phospholipase C, beta 4 H014981_01 NM_000933 283006 PLCB4 Inositol phosphate metabolism, Phosphatidylinositol signaling system, cell_signaling, signal_transduction 0.9133619 0.989
1176 tpoPathway_h BioCarta H002055_01 Info Growth factor receptor-bound protein 2 H002055_01 M96995 296381 GRB2 Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel … 0.0022348 1.459
1177 tpoPathway_h BioCarta H002893_01 Info V-raf-1 murine leukemia viral oncogene homolog 1 H002893_01 X03484 85181 RAF1 Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … 0.0062484 1.596
1178 tpoPathway_h BioCarta H001365_01 Info Protein kinase C, beta 1 H001365_01 X07109 77202 PRKCB1 Bioactive Peptide Induced Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Ion Channel and Phorbol Esters Signaling Pathway, T Cell Receptor Signaling Pathway, Phosphatidylinositol signaling system, angiogenesis, cell_cycle, cell_signaling, signal_transduction 0.0304335 1.379
1179 tpoPathway_h BioCarta H003178_01 Info Mitogen-activated protein kinase 3 H003178_01 X60188 861 MAPK3 Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … 0.0986041 1.184
1180 tpoPathway_h BioCarta H001600_01 Info RAS p21 protein activator (GTPase activating protein) 1 H001600_01 M23379 758 RASA1 EGF Signaling Pathway, HIV-I Nef: negative effector of Fas and TNF, IGF-1 Signaling Pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Regulation of Splicing through Sam68, Signaling of Hepatocyte Growth Factor Receptor, Sprouty regulation of tyrosine kinase signals, T Cell Receptor Signaling Pathway, TPO Signaling Pathway, cell_signaling, signal_transduction 0.1015906 0.844
1181 tpoPathway_h BioCarta H002261_01 Info Signal transducer and activator of transcription 5B H002261_01 U47686 244613 STAT5B 0.441402 1.071
1182 tpoPathway_h BioCarta H009068_01 Info Homo sapiens mRNA; cDNA DKFZp586N1323 (from clone DKFZp586N1323) H009068_01 AL080218 24064 0.509279 1.056
1183 tpoPathway_h BioCarta H002722_01 Info Mitogen-activated protein kinase kinase 1 H002722_01 L11284 3446 MAP2K1 Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … 0.7377933 0.973
1184 gleevecPathway_h BioCarta H002055_01 Info Growth factor receptor-bound protein 2 H002055_01 M96995 296381 GRB2 Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel … 0.0022348 1.459
1185 gleevecPathway_h BioCarta H002893_01 Info V-raf-1 murine leukemia viral oncogene homolog 1 H002893_01 X03484 85181 RAF1 Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … 0.0062484 1.596
1186 gleevecPathway_h BioCarta H003611_01 Info Mitogen-activated protein kinase kinase 4 H003611_01 L36870 75217 MAP2K4 Perou’s – Intrinsic – Breast-Cancer-Genes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Ceramide Signaling Pathway, EGF Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, Inhibition of Cellular Proliferation by Gleevec, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , PDGF Signaling Pathway, T Cell Receptor Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system 0.012502 0.753
1187 gleevecPathway_h BioCarta H003332_01 Info V-crk avian sarcoma virus CT10 oncogene homolog-like H003332_01 X59656 37078 CRKL IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, Signaling of Hepatocyte Growth Factor Receptor, tsonc 0.0164206 0.675
1188 gleevecPathway_h BioCarta H003178_01 Info Mitogen-activated protein kinase 3 H003178_01 X60188 861 MAPK3 Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … 0.0986041 1.184
1189 gleevecPathway_h BioCarta H003158_01 Info Mitogen-activated protein kinase 8 H003158_01 L26318 190913 MAPK8 Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig … 0.1287835 1.166
1190 gleevecPathway_h BioCarta H002091_01 Info V-myc avian myelocytomatosis viral oncogene homolog H002091_01 K02276 79070 MYC Cadmium induces DNA synthesis and proliferation in macrophages, CTCF: First Multivalent Nuclear Factor, Erk1/Erk2 Mapk Signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, MAP Kinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, Overview of telomerase protein component gene hTert Transcriptional Regulation , p38 MAPK Signaling Pathway , Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, WNT Signaling Pathway, gene_regulation, immunology, transcription, tsonc 0.1797519 0.824
1191 gleevecPathway_h BioCarta H003441_01 Info Breakpoint cluster region H003441_01 X02596 234799 BCR Inhibition of Cellular Proliferation by Gleevec, Integrin Signaling Pathway, immunology, tsonc 0.2521813 1.116
1192 gleevecPathway_h BioCarta H002261_01 Info Signal transducer and activator of transcription 5B H002261_01 U47686 244613 STAT5B 0.441402 1.071
1193 gleevecPathway_h BioCarta H009068_01 Info Homo sapiens mRNA; cDNA DKFZp586N1323 (from clone DKFZp586N1323) H009068_01 AL080218 24064 0.509279 1.056
1194 gleevecPathway_h BioCarta H003612_01 Info V-akt murine thymoma viral oncogene homolog 1 H003612_01 M63167 71816 AKT1 Actions of Nitric Oxide in the Heart, AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, B Cell Survival Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia and p53 in the Cardiovascular system, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, mTOR Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Phospholipase C Signaling Pathway, Phospholipids as signaling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Ras Signaling Pathway, Regulation … 0.6741257 1.038
1195 gleevecPathway_h BioCarta H002722_01 Info Mitogen-activated protein kinase kinase 1 H002722_01 L11284 3446 MAP2K1 Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … 0.7377933 0.973
1196 il2Pathway_h BioCarta H002055_01 Info Growth factor receptor-bound protein 2 H002055_01 M96995 296381 GRB2 Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel … 0.0022348 1.459
1197 il2Pathway_h BioCarta H002893_01 Info V-raf-1 murine leukemia viral oncogene homolog 1 H002893_01 X03484 85181 RAF1 Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … 0.0062484 1.596
1198 il2Pathway_h BioCarta H003718_01 Info Interleukin 2 receptor, gamma (severe combined immunodeficiency) H003718_01 D11086 84 IL2RG IL 2 signaling pathway, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, IL-7 Signal Transduction, immunology 0.0314631 1.258
1199 il2Pathway_h BioCarta H003178_01 Info Mitogen-activated protein kinase 3 H003178_01 X60188 861 MAPK3 Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … 0.0986041 1.184
1200 il2Pathway_h BioCarta H003158_01 Info Mitogen-activated protein kinase 8 H003158_01 L26318 190913 MAPK8 Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig … 0.1287835 1.166
1201 il2Pathway_h BioCarta H003820_01 Info Lymphocyte-specific protein tyrosine kinase H003820_01 X05027 1765 LCK Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, IL 2 signaling pathway, IL-7 Signal Transduction, Lck and Fyn tyrosine kinases in initiation of TCR Activation, T Cell Receptor Signaling Pathway, The Co-Stimulatory Signal During T-cell Activation, immunology, signal_transduction, tsonc 0.2266863 0.873
1202 il2Pathway_h BioCarta H001349_01 Info Janus kinase 1 (a protein tyrosine kinase) H001349_01 M64174 50651 JAK1 EGF Signaling Pathway, IFN alpha signaling pathway, IFN gamma signaling pathway , IL 2 signaling pathway, IL 4 signaling pathway, IL-10 Anti-inflammatory Signaling Pathway, IL-2 Receptor Beta Chain in T cell Activation, IL-7 Signal Transduction, PDGF Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction 0.2754104 1.129
1203 il2Pathway_h BioCarta H002261_01 Info Signal transducer and activator of transcription 5B H002261_01 U47686 244613 STAT5B 0.441402 1.071
1204 il2Pathway_h BioCarta H002824_01 Info Janus kinase 3 (a protein tyrosine kinase, leukocyte) H002824_01 U09607 99877 JAK3 IL 2 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, IL22 Soluble Receptor Signaling Pathway , IL-7 Signal Transduction, Stat3 Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction 0.4735774 1.051
1205 il2Pathway_h BioCarta H009068_01 Info Homo sapiens mRNA; cDNA DKFZp586N1323 (from clone DKFZp586N1323) H009068_01 AL080218 24064 0.509279 1.056
1206 il2Pathway_h BioCarta H003650_01 Info Interleukin 2 receptor, alpha H003650_01 X01057 1724 IL2RA IL 2 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Role of Tob in T-cell activation, Th1/Th2 Differentiation, immunology 0.5932248 1.054
1207 il2Pathway_h BioCarta H002570_01 Info Interleukin 2 H002570_01 S82692 89679 IL2 Antigen Dependent B Cell Activation, Cytokine Network, Cytokines and Inflammatory Response, IL 18 Signaling Pathway, IL 2 signaling pathway, OX40 Signaling Pathway, Regulation of hematopoiesis by cytokines, Role of Tob in T-cell activation, Selective expression of chemokine receptors during T-cell polarization, Th1/Th2 Differentiation, The 4-1BB-dependent immune response, The Co-Stimulatory Signal During T-cell Activation, immunology 0.6483346 1.043
1208 il2Pathway_h BioCarta H002722_01 Info Mitogen-activated protein kinase kinase 1 H002722_01 L11284 3446 MAP2K1 Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … 0.7377933 0.973
1209 pparaPathway_h BioCarta H003112_01 Info Retinoblastoma 1 (including osteosarcoma) H003112_01 L41870 75770 RB1 BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Chaperones modulate interferon Signaling Pathway, Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase RNA component gene hTerc Transcriptional Regulation, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Regulation of transcriptional activity by PML, Telomeres, Telomerase, Cellular Aging, and Immortality, TNFR1 Signaling Pathway, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, immunology, tsonc 0.0008596 0.674
1210 pparaPathway_h BioCarta H002547_01 Info Lipoprotein lipase H002547_01 M15856 180878 LPL Low-density lipoprotein (LDL) pathway during atherogenesis, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Role of PPAR-gamma Coactivators in Obesity and Thermogenesis, Visceral Fat Deposits and the Metabolic Syndrome, Glycerolipid metabolism, immunology 0.0011159 0.719
1211 pparaPathway_h BioCarta H000570_01 Info CREB binding protein (Rubinstein-Taybi syndrome) H000570_01 U47741 23598 CREBBP gene_regulation, transcription 0.0048718 1.469
1212 pparaPathway_h BioCarta H003415_01 Info Protein kinase, cAMP-dependent, catalytic, beta H003415_01 M34181 87773 PRKACB Perou’s – Intrinsic – Breast-Cancer-Genes, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.0048904 0.647
1213 pparaPathway_h BioCarta H003606_01 Info Retinoid X receptor, alpha H003606_01 U66306 20084 RXRA Basic mechanism of action of PPARa, PPARb(d) and PPARg and effects on gene expression, Control of Gene Expression by Vitamin D Receptor, Degradation of the RAR and RXR by the proteasome, FXR and LXR Regulation of Cholesterol Metabolism, Map Kinase Inactivation of SMRT Corepressor, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells, Role of PPAR-gamma Coactivators in Obesity and Thermogenesis, Transcription Regulation by Methyltransferase of CARM1, Visceral Fat Deposits and the Metabolic Syndrome, development, gene_regulation, transcription 0.0142664 1.308
1214 pparaPathway_h BioCarta H001365_01 Info Protein kinase C, beta 1 H001365_01 X07109 77202 PRKCB1 Bioactive Peptide Induced Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Ion Channel and Phorbol Esters Signaling Pathway, T Cell Receptor Signaling Pathway, Phosphatidylinositol signaling system, angiogenesis, cell_cycle, cell_signaling, signal_transduction 0.0304335 1.379
1215 pparaPathway_h BioCarta H001374_01 Info PPAR binding protein H001374_01 Y13467 15589 PPARBP Perou’s – Intrinsic – Breast-Cancer-Genes, CARM1 and Regulation of the Estrogen Receptor, Control of Gene Expression by Vitamin D Receptor, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Multi-step Regulation of Transcription by Pitx2, Role of PPAR-gamma Coactivators in Obesity and Thermogenesis 0.0333785 0.803
1216 pparaPathway_h BioCarta H002187_01 Info Nuclear receptor subfamily 2, group F, member 1 H002187_01 X16155 144630 NR2F1 Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha) 0.0403086 0.792
1217 pparaPathway_h BioCarta H003259_01 Info Sp1 transcription factor H003259_01 J03133 2021 SP1 Agrin in Postsynaptic Differentiation, Effects of calcineurin in Keratinocyte Differentiation, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase protein component gene hTert Transcriptional Regulation , Overview of telomerase RNA component gene hTerc Transcriptional Regulation 0.0557417 0.814
1218 pparaPathway_h BioCarta H003178_01 Info Mitogen-activated protein kinase 3 H003178_01 X60188 861 MAPK3 Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … 0.0986041 1.184
1219 pparaPathway_h BioCarta H008186_01 Info Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 H008186_01 AF109161 82071 CITED2 Perou’s – Intrinsic – Breast-Cancer-Genes, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha) 0.1031104 0.841
1220 pparaPathway_h BioCarta H003198_01 Info Fatty acid binding protein 1, liver H003198_01 M10050 5241 FABP1 Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), immunology 0.1414926 0.883
1221 pparaPathway_h BioCarta H002871_01 Info Apolipoprotein A-I H002871_01 X02162 93194 APOA1 Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), immunology 0.1551541 0.794
1222 pparaPathway_h BioCarta H002091_01 Info V-myc avian myelocytomatosis viral oncogene homolog H002091_01 K02276 79070 MYC Cadmium induces DNA synthesis and proliferation in macrophages, CTCF: First Multivalent Nuclear Factor, Erk1/Erk2 Mapk Signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, MAP Kinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, Overview of telomerase protein component gene hTert Transcriptional Regulation , p38 MAPK Signaling Pathway , Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, WNT Signaling Pathway, gene_regulation, immunology, transcription, tsonc 0.1797519 0.824
1223 pparaPathway_h BioCarta H013590_01 Info Nuclear receptor co-repressor 1 H013590_01 AF044209 144904 NCOR1 Control of Gene Expression by Vitamin D Receptor, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha) 0.2336483 0.899
1224 pparaPathway_h BioCarta H001698_01 Info Protein kinase, cAMP-dependent, regulatory, type II, alpha H001698_01 X14968 289075 PRKAR2A AKAP95 role in mitosis and chromosome dynamics, Protein Kinase A at the Centrosome, Rho-Selective Guanine Exchange Factor AKAP13 Mediates Stress Fiber Formation 0.2569617 1.125
1225 pparaPathway_h BioCarta H000174_01 Info Heat shock 90kD protein 1, alpha H000174_01 X15183 289088 HSPCA 0.3292659 0.896
1226 pparaPathway_h BioCarta H002882_01 Info Nuclear receptor co-repressor 2 H002882_01 NM_006312 287994 NCOR2 CARM1 and Regulation of the Estrogen Receptor, Map Kinase Inactivation of SMRT Corepressor, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), METS affect on Macrophage Differentiation, Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells 0.3492591 0.931
1227 pparaPathway_h BioCarta H007099_01 Info Choline kinase-like H007099_01 AL096780 154886 CHKL Fatty acid metabolism 0.3964303 0.907
1228 pparaPathway_h BioCarta H000645_01 Info Protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) H000645_01 M33336 183037 PRKAR1A Activation of cAMP-dependent protein kinase, PKA, cell_cycle, cell_signaling, signal_transduction 0.4305614 0.935
1229 pparaPathway_h BioCarta H002261_01 Info Signal transducer and activator of transcription 5B H002261_01 U47686 244613 STAT5B 0.441402 1.071
1230 pparaPathway_h BioCarta H002035_01 Info FAT tumor suppressor (Drosophila) homolog H002035_01 X87241 166994 FAT cell_signaling, immunology, metastasis, tsonc 0.4989072 0.922
1231 pparaPathway_h BioCarta H009068_01 Info Homo sapiens mRNA; cDNA DKFZp586N1323 (from clone DKFZp586N1323) H009068_01 AL080218 24064 0.509279 1.056
1232 pparaPathway_h BioCarta H000780_01 Info Nuclear receptor subfamily 1, group H, member 3 H000780_01 U22662 81336 NR1H3 FXR and LXR Regulation of Cholesterol Metabolism, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Nuclear Receptors in Lipid Metabolism and Toxicity 0.578592 1.089
1233 pparaPathway_h BioCarta H008686_01 Info DUTP pyrophosphatase H008686_01 U31930 82113 DUT Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Pyrimidine metabolism, gene_regulation, transcription 0.6087897 1.051
1234 pparaPathway_h BioCarta H003231_01 Info Platelet-derived growth factor alpha polypeptide H003231_01 X06374 37040 PDGFA Cytokines and Inflammatory Response, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), PDGF Signaling Pathway, Phospholipids as signaling intermediaries, immunology, misc, signal_transduction 0.6989894 1.039
1235 pparaPathway_h BioCarta H003875_01 Info Hydroxysteroid (17-beta) dehydrogenase 4 H003875_01 X87176 75441 HSD17B4 Perou’s – Intrinsic – Breast-Cancer-Genes, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Androgen and estrogen metabolism 0.7514294 0.968
1236 pparaPathway_h BioCarta H003434_01 Info Dual specificity phosphatase 1 H003434_01 NM_004417 171695 DUSP1 CD40L Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), NFkB activation by Nontypeable Hemophilus influenzae, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, TNFR2 Signaling Pathway 0.8183145 0.968
1237 pparaPathway_h BioCarta H002447_01 Info Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha H002447_01 M69043 81328 NFKBIA Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Signal transduction through IL1R, T Cell Receptor Signaling Pathway, The 4-1BB-dependent immune … 0.8245205 0.975
1238 pparaPathway_h BioCarta H002350_01 Info Peroxisome proliferative activated receptor, alpha H002350_01 L02932 998 PPARA Basic mechanism of action of PPARa, PPARb(d) and PPARg and effects on gene expression, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Nuclear Receptors in Lipid Metabolism and Toxicity, Regulation of PGC-1a, �-arrestins in GPCR Desensitization, Toll-Like Receptor Pathway 0.8655149 1.015
1239 pparaPathway_h BioCarta H015634_01 Info Heat shock 90kD protein 1, alpha H015634_01 NM_005348 289088 HSPCA 0.8774982 1.018
1240 pparaPathway_h BioCarta H003151_01 Info E1A binding protein p300 H003151_01 U01877 25272 EP300 Acetylation and Deacetylation of RelA in The Nucleus, CARM1 and Regulation of the Estrogen Receptor, Cell Cycle: G2/M Checkpoint, Control of Gene Expression by Vitamin D Receptor, Hypoxia and p53 in the Cardiovascular system, Hypoxia-Inducible Factor in the Cardiovascular System, IL-7 Signal Transduction, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Melanocyte Development and Pigmentation Pathway, Multi-step Regulation of Transcription by Pitx2, NFkB activation by Nontypeable Hemophilus influenzae, Pelp1 Modulation of Estrogen Receptor Activity, Role of ERBB2 in Signal Transduction and Oncology, Role of MEF2D in T-cell Apoptosis, Role of PPAR-gamma Coactivators in Obesity and Thermogenesis, TGF beta signaling pathway, Transcription Regulation by Methyltransferase of CARM1, gene_regulation, transcription 0.9607239 1.004
1241 pparaPathway_h BioCarta H002963_01 Info V-rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide H002963_01 L19067 75569 RELA Acetylation and Deacetylation of RelA in The Nucleus, Erythropoietin mediated neuroprotection through NF-kB, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, immunology, tsonc 0.9724165 1.003
1242 pparaPathway_h BioCarta H004913_01 Info CGI-113 protein H004913_01 NM_016050 152738 LOC51017 Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha) 0.9894647 0.999
1243 GNF_FEMALE_GENES_h na H006305_01 Info O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylgluco H006305_01 NM_003605 100293 OGT 0.0029258 1.335
1244 GNF_FEMALE_GENES_h na H000959_01 Info Glycophorin C (Gerbich blood group) H000959_01 NM_002101 81994 GYPC 0.0034104 1.545
1245 GNF_FEMALE_GENES_h na H009875_01 Info Lysosomal-associated multispanning membrane protein-5 H009875_01 U51240 79356 LAPTM5 0.0035021 1.539
1246 GNF_FEMALE_GENES_h na H000665_01 Info Guanylate binding protein 2, interferon-inducible H000665_01 M55543 171862 GBP2 cell_signaling 0.003713 1.543
1247 GNF_FEMALE_GENES_h na H009171_01 Info GRB2-associated binding protein 2 H009171_01 AB011143 30687 GAB2 0.0046478 1.423
1248 GNF_FEMALE_GENES_h na H012004_01 Info Retinal short-chain dehydrogenase/reductase retSDR2 H012004_01 NM_016245 12150 LOC51170 0.0066239 1.439
1249 GNF_FEMALE_GENES_h na H002047_01 Info Transforming growth factor, beta receptor III (betaglycan, 300kD) H002047_01 L07594 79059 TGFBR3 Perou’s – Intrinsic – Breast-Cancer-Genes, ALK in cardiac myocytes, CTCF: First Multivalent Nuclear Factor, Role of Tob in T-cell activation, immunology 0.0081449 0.728
1250 GNF_FEMALE_GENES_h na H001037_01 Info Proteoglycan 1, secretory granule H001037_01 X17042 1908 PRG1 immunology 0.0087226 1.629
1251 GNF_FEMALE_GENES_h na H014142_01 Info Sodium calcium exchanger H014142_01 NM_020689 12321 NCKX3 0.0169504 1.231
1252 GNF_FEMALE_GENES_h na H006288_01 Info AE-binding protein 1 H006288_01 AF053944 118397 AEBP1 0.0298793 0.787
1253 GNF_FEMALE_GENES_h na H000044_01 Info Ribosomal protein L31 H000044_01 X15940 184014 RPL31 0.0622533 0.75
1254 GNF_FEMALE_GENES_h na H003123_01 Info Nicotinamide N-methyltransferase H003123_01 U08021 76669 NNMT Nicotinate and nicotinamide metabolism, immunology 0.070177 0.777
1255 GNF_FEMALE_GENES_h na H000486_01 Info Interferon induced transmembrane protein 2 (1-8D) H000486_01 X57351 174195 IFITM2 0.0726328 0.803
1256 GNF_FEMALE_GENES_h na H001954_01 Info Milk fat globule-EGF factor 8 protein H001954_01 U58516 3745 MFGE8 Perou’s – Intrinsic – Breast-Cancer-Genes 0.082982 0.826
1257 GNF_FEMALE_GENES_h na H004936_01 Info DKFZP564A122 protein H004936_01 AL110269 187991 DKFZP564A122 0.0852946 1.175
1258 GNF_FEMALE_GENES_h na H002959_01 Info Small inducible cytokine subfamily A (Cys-Cys), member 21 H002959_01 AB002409 57907 SCYA21 0.0998916 0.822
1259 GNF_FEMALE_GENES_h na H003735_01 Info Insulin-like growth factor binding protein 5 H003735_01 AF055033 107169 IGFBP5 Perou’s – Intrinsic – Breast-Cancer-Genes, Ghrelin: Regulation of Food Intake and Energy Homeostasis 0.1007284 0.858
1260 GNF_FEMALE_GENES_h na H012158_01 Info Upregulated by 1,25-dihydroxyvitamin D-3 H012158_01 S73591 179526 VDUP1 0.1293789 1.193
1261 GNF_FEMALE_GENES_h na H005384_01 Info Homo sapiens mRNA; cDNA DKFZp564H0764 (from clone DKFZp564H0764) H005384_01 AL117617 239870 0.1303249 1.15
1262 GNF_FEMALE_GENES_h na H000774_01 Info Collagen, type VI, alpha 1 H000774_01 X15880 108885 COL6A1 0.1448402 0.841
1263 GNF_FEMALE_GENES_h na H010255_01 Info Ribosomal protein S17 H010255_01 M13932 5174 RPS17 0.1480605 1.185
1264 GNF_FEMALE_GENES_h na H002105_01 Info Ribosomal protein S3 H002105_01 X55715 252259 RPS3 0.1493113 1.139
1265 GNF_FEMALE_GENES_h na H000239_01 Info Microphthalmia-associated transcription factor H000239_01 AB006909 166017 MITF Melanocyte Development and Pigmentation Pathway, immunology 0.1500822 0.862
1266 GNF_FEMALE_GENES_h na H001266_01 Info RNA binding motif, single stranded interacting protein 1 H001266_01 X77494 241567 RBMS1 0.261805 1.109
1267 GNF_FEMALE_GENES_h na H000626_01 Info Ribosomal protein L10 H000626_01 M64241 29797 RPL10 Perou’s – Intrinsic – Breast-Cancer-Genes 0.2841001 0.912
1268 GNF_FEMALE_GENES_h na H001270_01 Info Interferon, gamma-inducible protein 16 H001270_01 M63838 155530 IFI16 cell_signaling 0.2909837 1.116
1269 GNF_FEMALE_GENES_h na H008012_01 Info Ribosomal protein S24 H008012_01 M31520 180450 RPS24 0.3379111 1.131
1270 GNF_FEMALE_GENES_h na H001198_01 Info Homo sapiens, alpha-1 (VI) collagen H001198_01 M20776 25459 0.3632512 1.1
1271 GNF_FEMALE_GENES_h na H006775_01 Info A disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 1 H006775_01 AB037767 8230 ADAMTS1 0.3720854 1.072
1272 GNF_FEMALE_GENES_h na H005212_01 Info C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 2 (activation H005212_01 X96719 85201 CLECSF2 0.3801627 1.089
1273 GNF_FEMALE_GENES_h na H005723_01 Info Ribosomal protein L34 H005723_01 L38941 250895 RPL34 0.4130435 1.133
1274 GNF_FEMALE_GENES_h na H003115_01 Info Low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) H003115_01 X13916 89137 LRP1 cell_cycle, cell_signaling, immunology 0.4443931 0.926
1275 GNF_FEMALE_GENES_h na H014105_01 Info Ribosomal protein L36a H014105_01 NM_001001 118857 RPL36A 0.4522347 1.101
1276 GNF_FEMALE_GENES_h na H012632_01 Info Ribosomal protein L9 H012632_01 U09953 157850 RPL9 0.5126569 1.077
1277 GNF_FEMALE_GENES_h na H000213_01 Info Eukaryotic translation initiation factor 3, subunit 6 (48kD) H000213_01 U62962 106673 EIF3S6 gene_regulation, immunology, transcription, tsonc 0.5258922 1.066
1278 GNF_FEMALE_GENES_h na H000034_01 Info Ribosomal protein L7 H000034_01 X57958 153 RPL7 0.5440511 1.085
1279 GNF_FEMALE_GENES_h na H007807_01 Info Ribosomal protein L39 H007807_01 D79205 300141 RPL39 0.550634 1.065
1280 GNF_FEMALE_GENES_h na H011160_01 Info Eukaryotic translation elongation factor 1 beta 1 H011160_01 X60656 261802 EEF1B1 0.5824813 1.068
1281 GNF_FEMALE_GENES_h na H002689_01 Info Ribosomal protein L15 H002689_01 L25899 74267 RPL15 0.6165764 0.94
1282 GNF_FEMALE_GENES_h na H012998_01 Info Homo sapiens cDNA FLJ11256 fis, clone PLACE1008925 H012998_01 AK002118 272247 0.6438646 1.044
1283 GNF_FEMALE_GENES_h na H007375_01 Info Hypothetical protein DKFZp586F2423 H007375_01 AL080209 13659 DKFZP586F2423 0.6776451 0.96
1284 GNF_FEMALE_GENES_h na H015333_01 Info Ribosomal protein L35a H015333_01 NM_000996 287361 RPL35A 0.7045738 1.05
1285 GNF_FEMALE_GENES_h na H000589_01 Info Cysteine-rich, angiogenic inducer, 61 H000589_01 Y11307 8867 CYR61 0.7640549 0.976
1286 GNF_FEMALE_GENES_h na H012850_01 Info Nucleosome assembly protein 1-like 1 H012850_01 AL162068 179662 NAP1L1 0.7805775 0.973
1287 GNF_FEMALE_GENES_h na H003196_01 Info Ribosomal protein L6 H003196_01 X69391 174131 RPL6 0.806836 1.029
1288 GNF_FEMALE_GENES_h na H006606_01 Info Ribosomal protein L24 H006606_01 M94314 184582 RPL24 0.8560724 1.02
1289 GNF_FEMALE_GENES_h na H009456_01 Info Ribosomal protein L17 H009456_01 X53777 82202 RPL17 0.8757496 0.983
1290 GNF_FEMALE_GENES_h na H012065_01 Info Ribosomal protein S4, X-linked H012065_01 M58458 108124 RPS4X immunology 0.8900601 1.017
1291 GNF_FEMALE_GENES_h na H000071_01 Info Ribosomal protein S3A H000071_01 M84711 77039 RPS3A 0.9635871 0.994
1292 GNF_FEMALE_GENES_h na H009310_01 Info Immunoglobulin superfamily containing leucine-rich repeat H009310_01 AB024536 102171 ISLR 0.9743631 0.997
1293 MAP00510_N_Glycans_biosynthesis_h GenMAPP H003208_01 Info Mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase H003208_01 NM_002408 172195 MGAT2 N-Glycan biosynthesis 0.0033074 0.717
1294 MAP00510_N_Glycans_biosynthesis_h GenMAPP H016058_01 Info UDP-Gal:beta GlcNAc beta 1,4- galactosyltransferase, polypeptide 3 H016058_01 NM_003779 321231 B4GALT3 Keratan sulfate biosynthesis, N-Glycan biosynthesis 0.0064647 0.72
1295 MAP00510_N_Glycans_biosynthesis_h GenMAPP H003403_01 Info Mannosidase, alpha, class 2A, member 1 H003403_01 D63998 32965 MAN2A1 N-Glycan biosynthesis 0.0334798 0.831
1296 MAP00510_N_Glycans_biosynthesis_h GenMAPP H001712_01 Info Dolichyl – diphosphooligosaccharide – protein glycosyltransferase H001712_01 D29643 34789 DDOST N-Glycan biosynthesis 0.1164599 0.856
1297 MAP00510_N_Glycans_biosynthesis_h GenMAPP H006144_01 Info UDP-Gal:beta GlcNAc beta 1,4- galactosyltransferase, polypeptide 3 H006144_01 AF038661 321231 B4GALT3 Keratan sulfate biosynthesis, N-Glycan biosynthesis 0.1629007 1.121
1298 MAP00510_N_Glycans_biosynthesis_h GenMAPP H001158_01 Info UDP-Gal:beta GlcNAc beta 1,4- galactosyltransferase, polypeptide 1 H001158_01 D29805 198248 B4GALT1 Perou’s – Intrinsic – Breast-Cancer-Genes, Galactose metabolism, Keratan sulfate biosynthesis, N-Glycan biosynthesis 0.1752304 1.141
1299 MAP00510_N_Glycans_biosynthesis_h GenMAPP H014296_01 Info Hypothetical protein FLJ21924 H014296_01 NM_024774 143509 FLJ21924 0.2628233 0.878
1300 MAP00510_N_Glycans_biosynthesis_h GenMAPP H001166_01 Info Glucosidase I H001166_01 X87237 83919 GCS1 ER associated degradation (ERAD) Pathway, N-Glycan biosynthesis 0.3340129 0.922
1301 MAP00510_N_Glycans_biosynthesis_h GenMAPP H001585_01 Info Mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase H001585_01 NM_002406 151513 MGAT1 N-Glycan biosynthesis 0.3439299 1.076
1302 MAP00510_N_Glycans_biosynthesis_h GenMAPP H016296_01 Info Dolichyl – diphosphooligosaccharide – protein glycosyltransferase H016296_01 NM_005216 34789 DDOST N-Glycan biosynthesis 0.4721938 0.93
1303 MAP00510_N_Glycans_biosynthesis_h GenMAPP H002721_01 Info Sialyltransferase 1 (beta-galactoside alpha-2,6-sialytransferase) H002721_01 X62822 2554 SIAT1 angiogenesis, metastasis 0.8087218 1.023
1304 CR_PROTEIN_MOD_h PNAS_2010 H003415_01 Info Protein kinase, cAMP-dependent, catalytic, beta H003415_01 M34181 87773 PRKACB Perou’s – Intrinsic – Breast-Cancer-Genes, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.0048904 0.647
1305 CR_PROTEIN_MOD_h PNAS_2010 H000599_01 Info Protein phosphatase 1D magnesium-dependent, delta isoform H000599_01 U78305 100980 PPM1D 0.0049252 1.53
1306 CR_PROTEIN_MOD_h PNAS_2010 H000474_01 Info Testis-specific kinase 1 H000474_01 D50863 79358 TESK1 cell_cycle, cell_signaling, signal_transduction 0.005093 1.591
1307 CR_PROTEIN_MOD_h PNAS_2010 H001868_01 Info Dual specificity phosphatase 9 H001868_01 Y08302 144879 DUSP9 Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases 0.0053314 0.725
1308 CR_PROTEIN_MOD_h PNAS_2010 H002290_01 Info Acid phosphatase 5, tartrate resistant H002290_01 NM_001611 1211 ACP5 gamma-Hexachlorocyclohexane degradation, Riboflavin metabolism, cell_cycle, cell_signaling, immunology 0.0064683 1.315
1309 CR_PROTEIN_MOD_h PNAS_2010 H002878_01 Info V-yes-1 Yamaguchi sarcoma viral related oncogene homolog H002878_01 M16038 80887 LYN BCR Signaling Pathway, Eph Kinases and ephrins support platelet aggregation, Fc Epsilon Receptor I Signaling in Mast Cells, Phosphoinositides and their downstream targets., immunology, signal_transduction, tsonc 0.0068841 1.545
1310 CR_PROTEIN_MOD_h PNAS_2010 H002847_01 Info Protein tyrosine phosphatase, receptor type, B H002847_01 X54131 123641 PTPRB Sprouty regulation of tyrosine kinase signals, cell_cycle, cell_signaling 0.0110757 1.299
1311 CR_PROTEIN_MOD_h PNAS_2010 H002041_01 Info Protein kinase, cAMP-dependent, catalytic, alpha H002041_01 X07767 77271 PRKACA Activation of cAMP-dependent protein kinase, PKA, AKAP95 role in mitosis and chromosome dynamics, Protein Kinase A at the Centrosome, Rho-Selective Guanine Exchange Factor AKAP13 Mediates Stress Fiber Formation, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.0156701 1.282
1312 CR_PROTEIN_MOD_h PNAS_2010 H003224_01 Info Ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) H003224_01 M30496 77917 UCHL3 0.0181978 0.767
1313 CR_PROTEIN_MOD_h PNAS_2010 H003305_01 Info Ribosomal protein S6 kinase, 70kD, polypeptide 1 H003305_01 M60724 86858 RPS6KB1 CTCF: First Multivalent Nuclear Factor, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, MAP Kinase Signaling Pathway, mTOR Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Rac 1 cell motility signaling pathway, Regulation of eIF4e and p70 S6 Kinase, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.0214523 1.448
1314 CR_PROTEIN_MOD_h PNAS_2010 H003028_01 Info Protein tyrosine phosphatase, receptor type, M H003028_01 X58288 154151 PTPRM Perou’s – Intrinsic – Breast-Cancer-Genes, cell_cycle, cell_signaling 0.0218926 0.763
1315 CR_PROTEIN_MOD_h PNAS_2010 H008575_01 Info Protein phosphatase 6, catalytic subunit H008575_01 X92972 279563 PPP6C Perou’s – Intrinsic – Breast-Cancer-Genes 0.0235177 0.753
1316 CR_PROTEIN_MOD_h PNAS_2010 H002124_01 Info Protein phosphatase 1, catalytic subunit, gamma isoform H002124_01 X74008 79081 PPP1CC cell_cycle, cell_signaling 0.02467 0.747
1317 CR_PROTEIN_MOD_h PNAS_2010 H003657_01 Info Protein kinase, interferon-inducible double stranded RNA dependent H003657_01 NM_002759 274382 PRKR cell_cycle, cell_signaling, signal_transduction 0.0267646 1.238
1318 CR_PROTEIN_MOD_h PNAS_2010 H001365_01 Info Protein kinase C, beta 1 H001365_01 X07109 77202 PRKCB1 Bioactive Peptide Induced Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Ion Channel and Phorbol Esters Signaling Pathway, T Cell Receptor Signaling Pathway, Phosphatidylinositol signaling system, angiogenesis, cell_cycle, cell_signaling, signal_transduction 0.0304335 1.379
1319 CR_PROTEIN_MOD_h PNAS_2010 H006644_01 Info Phosphorylase kinase, alpha 2 (liver) H006644_01 X80497 54941 PHKA2 cell_cycle, cell_signaling, signal_transduction 0.0321533 1.233
1320 CR_PROTEIN_MOD_h PNAS_2010 H001785_01 Info Hepsin (transmembrane protease, serine 1) H001785_01 X07732 823 HPN immunology 0.0349261 0.752
1321 CR_PROTEIN_MOD_h PNAS_2010 H002876_01 Info Protein tyrosine phosphatase, non-receptor type 2 H002876_01 M25393 82829 PTPN2 cell_cycle, cell_signaling 0.0354884 0.704
1322 CR_PROTEIN_MOD_h PNAS_2010 H001127_01 Info Leukocyte tyrosine kinase H001127_01 D16105 210 LTK cell_cycle, cell_signaling, immunology, signal_transduction 0.0368769 0.812
1323 CR_PROTEIN_MOD_h PNAS_2010 H000507_01 Info Tubulin-specific chaperone c H000507_01 U61234 75064 TBCC cell_signaling, metastasis 0.0442081 1.496
1324 CR_PROTEIN_MOD_h PNAS_2010 H002194_01 Info Casein kinase 1, alpha 1 H002194_01 L37042 283738 CSNK1A1 Deregulation of CDK5 in Alzheimer’s Disease, Hypoxia and p53 in the Cardiovascular system, NFAT and Hypertrophy of the heart (Transcription in the broken heart), WNT Signaling Pathway, cell_cycle, cell_signaling, signal_transduction 0.0461818 0.809
1325 CR_PROTEIN_MOD_h PNAS_2010 H000387_01 Info Cullin 2 H000387_01 U83410 82919 CUL2 0.0570922 0.832
1326 CR_PROTEIN_MOD_h PNAS_2010 H000521_01 Info Ribosomal protein S6 kinase, 90kD, polypeptide 2 H000521_01 X85106 301664 RPS6KA2 MAP Kinase Signaling Pathway, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.0604408 1.207
1327 CR_PROTEIN_MOD_h PNAS_2010 H000451_01 Info Protein tyrosine kinase 9 H000451_01 U02680 82643 PTK9 cell_cycle, cell_signaling, signal_transduction 0.0657095 0.808
1328 CR_PROTEIN_MOD_h PNAS_2010 H003873_01 Info Protein tyrosine phosphatase, receptor type, K H003873_01 L77886 79005 PTPRK Perou’s – Intrinsic – Breast-Cancer-Genes, cell_cycle, cell_signaling 0.0658539 0.801
1329 CR_PROTEIN_MOD_h PNAS_2010 H001676_01 Info Protein kinase C, iota H001676_01 L33881 1904 PRKCI Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.0761126 0.777
1330 CR_PROTEIN_MOD_h PNAS_2010 H002475_01 Info Pim-1 oncogene H002475_01 M54915 81170 PIM1 Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction, tsonc 0.0799298 1.166
1331 CR_PROTEIN_MOD_h PNAS_2010 H003808_01 Info V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog H003808_01 X06182 81665 KIT Perou’s – Intrinsic – Breast-Cancer-Genes, Melanocyte Development and Pigmentation Pathway, Regulation of BAD phosphorylation, immunology, tsonc 0.0813112 1.349
1332 CR_PROTEIN_MOD_h PNAS_2010 H003804_01 Info PTK7 protein tyrosine kinase 7 H003804_01 U33635 90572 PTK7 Perou’s – Intrinsic – Breast-Cancer-Genes, cell_cycle, cell_signaling, signal_transduction 0.0836802 0.82
1333 CR_PROTEIN_MOD_h PNAS_2010 H001730_01 Info Dual specificity phosphatase 7 H001730_01 X93921 296938 DUSP7 0.1170133 1.223
1334 CR_PROTEIN_MOD_h PNAS_2010 H002155_01 Info Casein kinase 1, delta H002155_01 U29171 75852 CSNK1D Regulation of ck1/cdk5 by type 1 glutamate receptors, cell_cycle, cell_signaling, signal_transduction 0.12119 0.868
1335 CR_PROTEIN_MOD_h PNAS_2010 H003207_01 Info V-abl Abelson murine leukemia viral oncogene homolog 1 H003207_01 NM_005157 146355 ABL1 cell_signaling, signal_transduction, tsonc 0.1292454 0.826
1336 CR_PROTEIN_MOD_h PNAS_2010 H015696_01 Info Cathepsin B H015696_01 NM_001908 297939 CTSB immunology, misc 0.1306532 1.18
1337 CR_PROTEIN_MOD_h PNAS_2010 H001631_01 Info Protein phosphatase 4 (formerly X), catalytic subunit H001631_01 AF097996 2903 PPP4C cell_cycle, cell_signaling 0.1363218 1.131
1338 CR_PROTEIN_MOD_h PNAS_2010 H002356_01 Info Alanyl (membrane) aminopeptidase (aminopeptidase N, aminopeptidase M, microsomal aminopeptidase, CD1 H002356_01 M22324 1239 ANPEP Dendritic cells in regulating TH1 and TH2 Development, SARS Coronavirus Protease, Glutathione metabolism, angiogenesis, immunology, metastasis 0.1526923 1.194
1339 CR_PROTEIN_MOD_h PNAS_2010 H002669_01 Info LIM domain kinase 2 H002669_01 NM_016733 278027 LIMK2 cell_cycle, cell_signaling, signal_transduction 0.1587394 1.231
1340 CR_PROTEIN_MOD_h PNAS_2010 H001679_01 Info Protein phosphatase, EF hand calcium-binding domain 1 H001679_01 X97867 211589 PPEF1 0.1646513 0.872
1341 CR_PROTEIN_MOD_h PNAS_2010 H001296_01 Info Protein tyrosine phosphatase, non-receptor type 7 H001296_01 M64322 35 PTPN7 T Cell Receptor Signaling Pathway, cell_cycle, cell_signaling 0.165907 0.84
1342 CR_PROTEIN_MOD_h PNAS_2010 H000198_01 Info V-ski avian sarcoma viral oncogene homolog H000198_01 X15218 2969 SKI tsonc 0.1691582 0.874
1343 CR_PROTEIN_MOD_h PNAS_2010 H003518_01 Info V-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene) H003518_01 M35296 121521 ABL2 cell_cycle, cell_signaling, signal_transduction, tsonc 0.1694499 1.149
1344 CR_PROTEIN_MOD_h PNAS_2010 H000558_01 Info Serine/threonine kinase 4 H000558_01 U60207 35140 STK4 Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.1725076 0.861
1345 CR_PROTEIN_MOD_h PNAS_2010 H003621_01 Info Fer (fps/fes related) tyrosine kinase (phosphoprotein NCP94) H003621_01 J03358 121558 FER signal_transduction, tsonc 0.1752525 0.868
1346 CR_PROTEIN_MOD_h PNAS_2010 H008496_01 Info Cullin 1 H008496_01 AF062536 14541 CUL1 Perou’s – Intrinsic – Breast-Cancer-Genes, Cyclin E Destruction Pathway, E2F1 Destruction Pathway, ER associated degradation (ERAD) Pathway, Regulation of p27 Phosphorylation during Cell Cycle Progression 0.1769614 1.122
1347 CR_PROTEIN_MOD_h PNAS_2010 H000644_01 Info Protein phosphatase 2, regulatory subunit B (B56), alpha isoform H000644_01 L42373 155079 PPP2R5A cell_cycle, cell_signaling, signal_transduction 0.1872145 0.884
1348 CR_PROTEIN_MOD_h PNAS_2010 H001706_01 Info Protein tyrosine phosphatase, non-receptor type 3 H001706_01 M64572 153932 PTPN3 cell_cycle, cell_signaling 0.2117298 1.123
1349 CR_PROTEIN_MOD_h PNAS_2010 H003820_01 Info Lymphocyte-specific protein tyrosine kinase H003820_01 X05027 1765 LCK Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, IL 2 signaling pathway, IL-7 Signal Transduction, Lck and Fyn tyrosine kinases in initiation of TCR Activation, T Cell Receptor Signaling Pathway, The Co-Stimulatory Signal During T-cell Activation, immunology, signal_transduction, tsonc 0.2266863 0.873
1350 CR_PROTEIN_MOD_h PNAS_2010 H002457_01 Info Protein kinase C, zeta H002457_01 Z15108 78793 PRKCZ Phosphoinositides and their downstream targets., Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.2375152 0.898
1351 CR_PROTEIN_MOD_h PNAS_2010 H003441_01 Info Breakpoint cluster region H003441_01 X02596 234799 BCR Inhibition of Cellular Proliferation by Gleevec, Integrin Signaling Pathway, immunology, tsonc 0.2521813 1.116
1352 CR_PROTEIN_MOD_h PNAS_2010 H003286_01 Info 3-phosphoinositide dependent protein kinase-1 H003286_01 AF017995 154729 PDPK1 Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.2543058 1.119
1353 CR_PROTEIN_MOD_h PNAS_2010 H000682_01 Info Phosphorylase kinase, gamma 2 (testis) H000682_01 M31606 196177 PHKG2 cell_cycle, cell_signaling, signal_transduction 0.2546262 1.097
1354 CR_PROTEIN_MOD_h PNAS_2010 H001876_01 Info 3′-phosphoadenosine 5′-phosphosulfate synthase 1 H001876_01 AF105227 3833 PAPSS1 Purine metabolism, Selenoamino acid metabolism, Sulfur metabolism 0.2713835 0.89
1355 CR_PROTEIN_MOD_h PNAS_2010 H001393_01 Info Protein tyrosine phosphatase type IVA, member 2 H001393_01 AF208850 82911 PTP4A2 0.2727324 0.892
1356 CR_PROTEIN_MOD_h PNAS_2010 H002947_01 Info Protein phosphatase 1, catalytic subunit, alpha isoform H002947_01 S57501 183994 PPP1CA cell_cycle, cell_signaling 0.2817559 1.112
1357 CR_PROTEIN_MOD_h PNAS_2010 H003484_01 Info B lymphoid tyrosine kinase H003484_01 S76617 2243 BLK cell_cycle, cell_signaling, immunology, signal_transduction 0.3077997 1.161
1358 CR_PROTEIN_MOD_h PNAS_2010 H000392_01 Info Human renal cell carcinoma antigen RAGE-4 mRNA, complete putative CDS H000392_01 U46194 189253 Phosphatidylinositol signaling system 0.3127126 0.9
1359 CR_PROTEIN_MOD_h PNAS_2010 H001273_01 Info BMX non-receptor tyrosine kinase H001273_01 AF045459 27372 BMX cell_cycle, cell_signaling, signal_transduction 0.3145394 0.907
1360 CR_PROTEIN_MOD_h PNAS_2010 H002235_01 Info Ubiquitin specific protease 6 (Tre-2 oncogene) H002235_01 X63547 111065 USP6 tsonc 0.3321253 0.887
1361 CR_PROTEIN_MOD_h PNAS_2010 H000617_01 Info Protein phosphatase 2, regulatory subunit B (B56), beta isoform H000617_01 L42374 75199 PPP2R5B cell_cycle, cell_signaling, signal_transduction 0.3383822 1.102
1362 CR_PROTEIN_MOD_h PNAS_2010 H001979_01 Info Protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform (calcineurin A beta) H001979_01 M29551 151531 PPP3CB cell_cycle, cell_signaling 0.3386238 0.898
1363 CR_PROTEIN_MOD_h PNAS_2010 H002948_01 Info Ubiquitin specific protease 4 (proto-oncogene) H002948_01 U20657 77500 USP4 tsonc 0.3395867 1.14
1364 CR_PROTEIN_MOD_h PNAS_2010 H003637_01 Info Protein tyrosine phosphatase, non-receptor type 12 H003637_01 M93425 62 PTPN12 cell_cycle, cell_signaling 0.3503541 1.098
1365 CR_PROTEIN_MOD_h PNAS_2010 H003877_01 Info Paired basic amino acid cleaving enzyme (furin, membrane associated receptor protein) H003877_01 X17094 59242 PACE Proteolysis and Signaling Pathway of Notch 0.3592119 1.111
1366 CR_PROTEIN_MOD_h PNAS_2010 H001703_01 Info Protein phosphatase 2 (formerly 2A), regulatory subunit B” (PR 72), alpha isoform and (PR 130), bet H001703_01 L07590 28219 PPP2R3 0.3677168 0.922
1367 CR_PROTEIN_MOD_h PNAS_2010 H015748_01 Info Serine/threonine kinase 11 (Peutz-Jeghers syndrome) H015748_01 NM_000455 301772 STK11 Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.3807438 1.093
1368 CR_PROTEIN_MOD_h PNAS_2010 H003351_01 Info Protein kinase, DNA-activated, catalytic polypeptide H003351_01 U47077 155637 PRKDC Cell Cycle: G2/M Checkpoint, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, TNFR1 Signaling Pathway, Phosphatidylinositol signaling system, DNA_damage, immunology 0.3847336 0.919
1369 CR_PROTEIN_MOD_h PNAS_2010 H001347_01 Info Protein tyrosine phosphatase, non-receptor type 18 (brain-derived) H001347_01 X79568 278597 PTPN18 0.3923457 0.914
1370 CR_PROTEIN_MOD_h PNAS_2010 H015456_01 Info Homo sapiens mRNA for FLJ00047 protein, partial CDS H015456_01 AK024455 287753 Perou’s – Intrinsic – Breast-Cancer-Genes, cell_cycle, cell_signaling 0.4000256 1.107
1371 CR_PROTEIN_MOD_h PNAS_2010 H000645_01 Info Protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) H000645_01 M33336 183037 PRKAR1A Activation of cAMP-dependent protein kinase, PKA, cell_cycle, cell_signaling, signal_transduction 0.4305614 0.935
1372 CR_PROTEIN_MOD_h PNAS_2010 H003529_01 Info ELK3, ETS-domain protein (SRF accessory protein 2) H003529_01 Z36715 121529 ELK3 tsonc 0.4403881 0.913
1373 CR_PROTEIN_MOD_h PNAS_2010 H015286_01 Info Homo sapiens PAK2 mRNA, complete CDS H015286_01 AF092132 284275 FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, MAP Kinase Signaling Pathway, TNFR1 Signaling Pathway, Phosphatidylinositol signaling system 0.4868167 1.068
1374 CR_PROTEIN_MOD_h PNAS_2010 H007319_01 Info Histone deacetylase 5 H007319_01 NM_005474 9028 HDAC5 Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Regulation of PGC-1a 0.5427846 1.062
1375 CR_PROTEIN_MOD_h PNAS_2010 H005412_01 Info Protein phosphatase 2, regulatory subunit B (B56), delta isoform H005412_01 L76702 118244 PPP2R5D cell_cycle, cell_signaling, signal_transduction 0.5741013 1.063
1376 CR_PROTEIN_MOD_h PNAS_2010 H013300_01 Info Pyruvate dehydrogenase kinase, isoenzyme 2 H013300_01 L42451 92261 PDK2 mTOR Signaling Pathway, PTEN dependent cell cycle arrest and apoptosis, Regulation of eIF4e and p70 S6 Kinase, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, cell_cycle, cell_signaling, signal_transduction 0.5991595 0.949
1377 CR_PROTEIN_MOD_h PNAS_2010 H002812_01 Info Protein tyrosine phosphatase, receptor type, C H002812_01 Y00062 170121 PTPRC Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, B Lymphocyte Cell Surface Molecules, Lck and Fyn tyrosine kinases in initiation of TCR Activation, T Cytotoxic Cell Surface Molecules, T Helper Cell Surface Molecules, cell_cycle, cell_signaling, immunology 0.6066202 1.093
1378 CR_PROTEIN_MOD_h PNAS_2010 H001923_01 Info Protein kinase, cGMP-dependent, type I H001923_01 Y07512 2689 PRKG1 Phosphatidylinositol signaling system, cell_cycle, cell_signaling, immunology, signal_transduction 0.6231152 0.956
1379 CR_PROTEIN_MOD_h PNAS_2010 H001896_01 Info Protein phosphatase 1, catalytic subunit, beta isoform H001896_01 X80910 21537 PPP1CB cell_cycle, cell_signaling 0.6410125 0.947
1380 CR_PROTEIN_MOD_h PNAS_2010 H002495_01 Info Protein tyrosine phosphatase, receptor type, N H002495_01 L18983 89655 PTPRN cell_cycle, cell_signaling 0.6620657 0.963
1381 CR_PROTEIN_MOD_h PNAS_2010 H003698_01 Info Protein tyrosine phosphatase, non-receptor type 1 H003698_01 M31724 155894 PTPN1 cell_cycle, cell_signaling 0.6633733 1.054
1382 CR_PROTEIN_MOD_h PNAS_2010 H001721_01 Info Protein phosphatase 5, catalytic subunit H001721_01 X89416 75180 PPP5C 0.6792992 1.036
1383 CR_PROTEIN_MOD_h PNAS_2010 H000479_01 Info Dual specificity phosphatase 8 H000479_01 U27193 41688 DUSP8 Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases 0.7214843 1.03
1384 CR_PROTEIN_MOD_h PNAS_2010 H007840_01 Info KIAA0508 protein H007840_01 AB007977 270010 KIAA0508 tsonc 0.7438349 1.027
1385 CR_PROTEIN_MOD_h PNAS_2010 H001646_01 Info Dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) H001646_01 AL049417 181046 DUSP3 cell_cycle, cell_signaling 0.7811469 0.968
1386 CR_PROTEIN_MOD_h PNAS_2010 H001681_01 Info Protein kinase C, theta H001681_01 L01087 211593 PRKCQ Keratinocyte Differentiation, cell_cycle, cell_signaling, immunology, signal_transduction 0.8037373 1.019
1387 CR_PROTEIN_MOD_h PNAS_2010 H002721_01 Info Sialyltransferase 1 (beta-galactoside alpha-2,6-sialytransferase) H002721_01 X62822 2554 SIAT1 angiogenesis, metastasis 0.8087218 1.023
1388 CR_PROTEIN_MOD_h PNAS_2010 H003160_01 Info RYK receptor-like tyrosine kinase H003160_01 S59184 79350 RYK cell_cycle, cell_signaling, signal_transduction 0.8388374 0.98
1389 CR_PROTEIN_MOD_h PNAS_2010 H001596_01 Info Protein kinase C, gamma H001596_01 Z15114 2890 PRKCG Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.8498034 1.018
1390 CR_PROTEIN_MOD_h PNAS_2010 H001376_01 Info Homo sapiens mRNA; cDNA DKFZp566L084 (from clone DKFZp566L084) H001376_01 AL133012 306440 Acetylation and Deacetylation of RelA in The Nucleus, AKT Signaling Pathway, CD40L Signaling Pathway, Double Stranded RNA Induced Gene Expression, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Ras Signaling Pathway, Signal transduction through IL1R, TACI and BCMA stimulation of B cell immune responses., The 4-1BB-dependent immune response, TNF/Stress Related Signaling, TNFR2 Signaling Pathway, Toll-Like Receptor Pathway, cell_cycle, cell_signaling, signal_transduction 0.8639394 0.98
1391 CR_PROTEIN_MOD_h PNAS_2010 H003541_01 Info Protein tyrosine phosphatase, non-receptor type 9 H003541_01 M83738 147663 PTPN9 cell_cycle, cell_signaling 0.8676444 1.016
1392 CR_PROTEIN_MOD_h PNAS_2010 H002806_01 Info Protein tyrosine phosphatase, receptor type, N polypeptide 2 H002806_01 U66702 74624 PTPRN2 Perou’s – Intrinsic – Breast-Cancer-Genes, cell_cycle, cell_signaling 0.8826274 1.014
1393 CR_PROTEIN_MOD_h PNAS_2010 H003074_01 Info Protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform H003074_01 M64929 179574 PPP2R2A cell_cycle, cell_signaling 0.9053085 0.989
1394 CR_PROTEIN_MOD_h PNAS_2010 H001766_01 Info Protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) H001766_01 M68941 73826 PTPN4 cell_cycle, cell_signaling 0.9219914 0.991
1395 CR_PROTEIN_MOD_h PNAS_2010 H001353_01 Info Casein kinase 1, epsilon H001353_01 AB024597 79658 CSNK1E Circadian Rhythms, cell_cycle, cell_signaling, signal_transduction 0.9225285 1.008
1396 CR_PROTEIN_MOD_h PNAS_2010 H000464_01 Info Protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform H000464_01 M65254 108705 PPP2R1B cell_cycle, cell_signaling 0.9562489 0.994
1397 CR_PROTEIN_MOD_h PNAS_2010 H003151_01 Info E1A binding protein p300 H003151_01 U01877 25272 EP300 Acetylation and Deacetylation of RelA in The Nucleus, CARM1 and Regulation of the Estrogen Receptor, Cell Cycle: G2/M Checkpoint, Control of Gene Expression by Vitamin D Receptor, Hypoxia and p53 in the Cardiovascular system, Hypoxia-Inducible Factor in the Cardiovascular System, IL-7 Signal Transduction, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Melanocyte Development and Pigmentation Pathway, Multi-step Regulation of Transcription by Pitx2, NFkB activation by Nontypeable Hemophilus influenzae, Pelp1 Modulation of Estrogen Receptor Activity, Role of ERBB2 in Signal Transduction and Oncology, Role of MEF2D in T-cell Apoptosis, Role of PPAR-gamma Coactivators in Obesity and Thermogenesis, TGF beta signaling pathway, Transcription Regulation by Methyltransferase of CARM1, gene_regulation, transcription 0.9607239 1.004
1398 CR_PROTEIN_MOD_h PNAS_2010 H001715_01 Info Dual specificity phosphatase 4 H001715_01 AL137704 2359 DUSP4 Perou’s – Intrinsic – Breast-Cancer-Genes, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, cell_cycle, cell_signaling 0.9634643 1.004
1399 CR_PROTEIN_MOD_h PNAS_2010 H001448_01 Info HtrA-like serine protease H001448_01 NM_013247 115721 OMI 0.9961185 1
1400 p27Pathway_h BioCarta H003112_01 Info Retinoblastoma 1 (including osteosarcoma) H003112_01 L41870 75770 RB1 BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Chaperones modulate interferon Signaling Pathway, Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase RNA component gene hTerc Transcriptional Regulation, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Regulation of transcriptional activity by PML, Telomeres, Telomerase, Cellular Aging, and Immortality, TNFR1 Signaling Pathway, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, immunology, tsonc 0.0008596 0.674
1401 p27Pathway_h BioCarta H002412_01 Info Cyclin-dependent kinase 2 H002412_01 M68520 19192 CDK2 CDK Regulation of DNA Replication, Cell Cycle: G1/S Check Point , Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, immunology, signal_transduction 0.0040171 0.711
1402 p27Pathway_h BioCarta H002802_01 Info Neural precursor cell expressed, developmentally down-regulated 8 H002802_01 D23662 75512 NEDD8 Regulation of p27 Phosphorylation during Cell Cycle Progression 0.0045178 1.293
1403 p27Pathway_h BioCarta H002323_01 Info Cyclin E1 H002323_01 M74093 9700 CCNE1 Perou’s – Intrinsic – Breast-Cancer-Genes, CDK Regulation of DNA Replication, Cell Cycle: G1/S Check Point , Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, Regulation of p27 Phosphorylation during Cell Cycle Progression, cell_cycle 0.1107382 0.884
1404 p27Pathway_h BioCarta H008496_01 Info Cullin 1 H008496_01 AF062536 14541 CUL1 Perou’s – Intrinsic – Breast-Cancer-Genes, Cyclin E Destruction Pathway, E2F1 Destruction Pathway, ER associated degradation (ERAD) Pathway, Regulation of p27 Phosphorylation during Cell Cycle Progression 0.1769614 1.122
1405 p27Pathway_h BioCarta H003109_01 Info CDC28 protein kinase 1 H003109_01 X54941 77550 CKS1 Regulation of p27 Phosphorylation during Cell Cycle Progression 0.3099586 1.102
1406 p27Pathway_h BioCarta H009086_01 Info S-phase kinase-associated protein 2 (p45) H009086_01 U33761 23348 SKP2 Cell Cycle: G1/S Check Point , E2F1 Destruction Pathway, Regulation of p27 Phosphorylation during Cell Cycle Progression 0.330649 1.089
1407 p27Pathway_h BioCarta H008244_01 Info S-phase kinase-associated protein 1A (p19A) H008244_01 U33760 227950 SKP1A Cyclin E Destruction Pathway, E2F1 Destruction Pathway, ER associated degradation (ERAD) Pathway, Regulation of p27 Phosphorylation during Cell Cycle Progression 0.4920203 0.951
1408 p27Pathway_h BioCarta H011149_01 Info Ring-box 1 H011149_01 NM_014248 279919 RBX1 ER associated degradation (ERAD) Pathway, Regulation of p27 Phosphorylation during Cell Cycle Progression 0.603709 1.055
1409 p27Pathway_h BioCarta H003162_01 Info Transcription factor Dp-1 H003162_01 L23959 279576 TFDP1 Cell Cycle: G1/S Check Point , Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, Influence of Ras and Rho proteins on G1 to S Transition, Regulation of p27 Phosphorylation during Cell Cycle Progression 0.6646128 0.958
1410 SA_PTEN_PATHWAY_h SigmaAldrich H002055_01 Info Growth factor receptor-bound protein 2 H002055_01 M96995 296381 GRB2 Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel … 0.0022348 1.459
1411 SA_PTEN_PATHWAY_h SigmaAldrich H003191_01 Info Retinoblastoma-like 2 (p130) H003191_01 X76061 79362 RBL2 METS affect on Macrophage Differentiation 0.00669 0.724
1412 SA_PTEN_PATHWAY_h SigmaAldrich H002573_01 Info Protein tyrosine kinase 2 beta H002573_01 U43522 20313 PTK2B Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CXCR4 Signaling Pathway, IL-7 Signal Transduction, Ion Channel and Phorbol Esters Signaling Pathway, Links between Pyk2 and Map Kinases, Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Signaling of Hepatocyte Growth Factor Receptor, Thrombin signaling and protease-activated receptors, angiogenesis, immunology, signal_transduction 0.0091935 1.367
1413 SA_PTEN_PATHWAY_h SigmaAldrich H001348_01 Info Phosphoinositide-3-kinase, catalytic, delta polypeptide H001348_01 U86453 162808 PIK3CD Inositol phosphate metabolism, Phosphatidylinositol signaling system 0.0324563 1.426
1414 SA_PTEN_PATHWAY_h SigmaAldrich H016134_01 Info V-akt murine thymoma viral oncogene homolog 2 H016134_01 NM_001626 326445 AKT2 Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction, tsonc 0.0530988 1.287
1415 SA_PTEN_PATHWAY_h SigmaAldrich H003178_01 Info Mitogen-activated protein kinase 3 H003178_01 X60188 861 MAPK3 Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … 0.0986041 1.184
1416 SA_PTEN_PATHWAY_h SigmaAldrich H004340_01 Info 3′(2′), 5′-bisphosphate nucleotidase 1 H004340_01 NM_006085 271752 BPNT1 Sulfur metabolism 0.1694685 1.176
1417 SA_PTEN_PATHWAY_h SigmaAldrich H002970_01 Info Integrin-linked kinase H002970_01 U40282 6196 ILK PTEN dependent cell cycle arrest and apoptosis, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.1701136 1.128
1418 SA_PTEN_PATHWAY_h SigmaAldrich H003497_01 Info V-akt murine thymoma viral oncogene homolog 2 H003497_01 M77198 326445 AKT2 Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction, tsonc 0.3314111 0.872
1419 SA_PTEN_PATHWAY_h SigmaAldrich H003612_01 Info V-akt murine thymoma viral oncogene homolog 1 H003612_01 M63167 71816 AKT1 Actions of Nitric Oxide in the Heart, AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, B Cell Survival Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia and p53 in the Cardiovascular system, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, mTOR Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Phospholipase C Signaling Pathway, Phospholipids as signaling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Ras Signaling Pathway, Regulation … 0.6741257 1.038
1420 CR_TRANSPORT_OF_VESICLES_h PNAS_2015 H003000_01 Info RAB5A, member RAS oncogene family H003000_01 M28215 73957 RAB5A Phosphoinositides and their downstream targets., Rab GTPases Mark Targets In The Endocytotic Machinery, The role of FYVE-finger proteins in vesicle transport, tsonc 0.0003278 0.591
1421 CR_TRANSPORT_OF_VESICLES_h PNAS_2015 H002296_01 Info RAB5B, member RAS oncogene family H002296_01 X54871 77690 RAB5B tsonc 0.0071339 1.264
1422 CR_TRANSPORT_OF_VESICLES_h PNAS_2015 H001623_01 Info RAB3A, member RAS oncogene family H001623_01 M28210 27744 RAB3A Rab GTPases Mark Targets In The Endocytotic Machinery, tsonc 0.0155278 0.773
1423 CR_TRANSPORT_OF_VESICLES_h PNAS_2015 H001739_01 Info Adaptor-related protein complex 2, mu 1 subunit H001739_01 D63475 152936 AP2M1 0.0326931 0.787
1424 CR_TRANSPORT_OF_VESICLES_h PNAS_2015 H001641_01 Info RAB5C, member RAS oncogene family H001641_01 U18420 479 RAB5C 0.124762 1.135
1425 CR_TRANSPORT_OF_VESICLES_h PNAS_2015 H001711_01 Info RAB3B, member RAS oncogene family H001711_01 M28214 123072 RAB3B tsonc 0.1338843 0.849
1426 CR_TRANSPORT_OF_VESICLES_h PNAS_2015 H001622_01 Info RAB31, member RAS oncogene family H001622_01 U59877 223025 RAB31 Perou’s – Intrinsic – Breast-Cancer-Genes 0.152499 1.183
1427 CR_TRANSPORT_OF_VESICLES_h PNAS_2015 H001723_01 Info RAB4, member RAS oncogene family H001723_01 M28211 119007 RAB4 Rab GTPases Mark Targets In The Endocytotic Machinery 0.1838619 0.841
1428 CR_TRANSPORT_OF_VESICLES_h PNAS_2015 H001731_01 Info RAB6A, member RAS oncogene family H001731_01 AF052130 5636 RAB6A Rab GTPases Mark Targets In The Endocytotic Machinery 0.2234269 1.121
1429 CR_TRANSPORT_OF_VESICLES_h PNAS_2015 H001719_01 Info Golgi autoantigen, golgin subfamily a, 4 H001719_01 X82834 183773 GOLGA4 0.2608724 0.87
1430 CR_TRANSPORT_OF_VESICLES_h PNAS_2015 H002973_01 Info RAB1, member RAS oncogene family H002973_01 M28209 3642 RAB1 Rab GTPases Mark Targets In The Endocytotic Machinery 0.292711 1.103
1431 CR_TRANSPORT_OF_VESICLES_h PNAS_2015 H005768_01 Info ARP1 (actin-related protein 1, yeast) homolog A (centractin alpha) H005768_01 X82206 153961 ACTR1A 0.2959858 1.106
1432 CR_TRANSPORT_OF_VESICLES_h PNAS_2015 H007601_01 Info RAB27A, member RAS oncogene family H007601_01 U57094 50477 RAB27A Rab GTPases Mark Targets In The Endocytotic Machinery, tsonc 0.6368779 1.053
1433 CR_TRANSPORT_OF_VESICLES_h PNAS_2015 H001985_01 Info RAB13, member RAS oncogene family H001985_01 X75593 151536 RAB13 tsonc 0.6547022 0.954
1434 CR_TRANSPORT_OF_VESICLES_h PNAS_2015 H012333_01 Info RAB27B, member RAS oncogene family H012333_01 NM_004163 97189 RAB27B tsonc 0.6900974 0.957
1435 CR_TRANSPORT_OF_VESICLES_h PNAS_2015 H001910_01 Info RAB11A, member RAS oncogene family H001910_01 AF000231 75618 RAB11A Rab GTPases Mark Targets In The Endocytotic Machinery, tsonc 0.7408236 1.034
1436 CR_TRANSPORT_OF_VESICLES_h PNAS_2015 H010181_01 Info RAB7, member RAS oncogene family-like 1 H010181_01 D84488 115325 RAB7L1 tsonc 0.7680291 0.961
1437 CR_TRANSPORT_OF_VESICLES_h PNAS_2015 H009706_01 Info RAB1, member RAS oncogene family H009706_01 AL050268 3642 RAB1 Rab GTPases Mark Targets In The Endocytotic Machinery 0.7686339 0.971
1438 il1rPathway_h BioCarta H003352_01 Info Interleukin 1 receptor, type I H003352_01 M27492 82112 IL1R1 NF-kB Signaling Pathway, Signal transduction through IL1R, immunology 0.000502 0.677
1439 il1rPathway_h BioCarta H003200_01 Info Mitogen-activated protein kinase kinase 3 H003200_01 D87116 180533 MAP2K3 fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Signal transduction through IL1R, TNF/Stress Related Signaling, Toll-Like Receptor Pathway 0.0009666 1.561
1440 il1rPathway_h BioCarta H003232_01 Info Mitogen-activated protein kinase kinase kinase 14 H003232_01 Y10256 47007 MAP3K14 CD40L Signaling Pathway, Double Stranded RNA Induced Gene Expression, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Keratinocyte Differentiation, MAP Kinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Signal transduction through IL1R, TACI and BCMA stimulation of B cell immune responses., TNF/Stress Related Signaling, TNFR2 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system 0.005309 0.755
1441 il1rPathway_h BioCarta H002895_01 Info Mitogen-activated protein kinase 14 H002895_01 L35263 79107 MAPK14 BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAP Kinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm … 0.0086925 1.429
1442 il1rPathway_h BioCarta H000657_01 Info Myeloid differentiation primary response gene (88) H000657_01 U70451 82116 MYD88 Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Signal transduction through IL1R, Toll-Like Receptor Pathway, apoptosis, immunology, misc 0.0732203 1.23
1443 il1rPathway_h BioCarta H003158_01 Info Mitogen-activated protein kinase 8 H003158_01 L26318 190913 MAPK8 Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig … 0.1287835 1.166
1444 il1rPathway_h BioCarta H007884_01 Info TOLLIP protein H007884_01 AJ242972 25413 LOC54472 Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Signal transduction through IL1R, Toll-Like Receptor Pathway 0.3826742 0.898
1445 il1rPathway_h BioCarta H001957_01 Info Interleukin 1, beta H001957_01 M15330 126256 IL1B IL 5 Signaling Pathway, Msp/Ron Receptor Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Signal transduction through IL1R, immunology 0.4390274 1.089
1446 il1rPathway_h BioCarta H006060_01 Info ECSIT H006060_01 AF243044 22199 LOC51295 Signal transduction through IL1R, Toll-Like Receptor Pathway 0.525719 1.065
1447 il1rPathway_h BioCarta H003110_01 Info Interleukin 6 (interferon, beta 2) H003110_01 X04430 93913 IL6 Cells and Molecules involved in local acute inflammatory response, Cytokine Network, Cytokines and Inflammatory Response, Erythrocyte Differentiation Pathway, IL 17 Signaling Pathway, IL 5 Signaling Pathway, IL 6 signaling pathway, IL-10 Anti-inflammatory Signaling Pathway, Low-density lipoprotein (LDL) pathway during atherogenesis, Regulation of hematopoiesis by cytokines, Role of ERBB2 in Signal Transduction and Oncology, Signal transduction through IL1R, immunology 0.680804 1.036
1448 il1rPathway_h BioCarta H002447_01 Info Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha H002447_01 M69043 81328 NFKBIA Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Signal transduction through IL1R, T Cell Receptor Signaling Pathway, The 4-1BB-dependent immune … 0.8245205 0.975
1449 il1rPathway_h BioCarta H002076_01 Info Interleukin-1 receptor-associated kinase 1 H002076_01 L76191 182018 IRAK1 Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, NF-kB Signaling Pathway, Toll-Like Receptor Pathway, immunology, signal_transduction 0.8472418 0.982
1450 il1rPathway_h BioCarta H001376_01 Info Homo sapiens mRNA; cDNA DKFZp566L084 (from clone DKFZp566L084) H001376_01 AL133012 306440 Acetylation and Deacetylation of RelA in The Nucleus, AKT Signaling Pathway, CD40L Signaling Pathway, Double Stranded RNA Induced Gene Expression, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Ras Signaling Pathway, Signal transduction through IL1R, TACI and BCMA stimulation of B cell immune responses., The 4-1BB-dependent immune response, TNF/Stress Related Signaling, TNFR2 Signaling Pathway, Toll-Like Receptor Pathway, cell_cycle, cell_signaling, signal_transduction 0.8639394 0.98
1451 il1rPathway_h BioCarta H003711_01 Info Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) H003711_01 M58603 83428 NFKB1 Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Bone Remodelling, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Ceramide Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Corticosteroids and cardioprotection, CXCR4 Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, Free Radical Induced Apoptosis, HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of a … 0.8665095 1.017
1452 il1rPathway_h BioCarta H002963_01 Info V-rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide H002963_01 L19067 75569 RELA Acetylation and Deacetylation of RelA in The Nucleus, Erythropoietin mediated neuroprotection through NF-kB, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, immunology, tsonc 0.9724165 1.003
1453 tollPathway_h BioCarta H003200_01 Info Mitogen-activated protein kinase kinase 3 H003200_01 D87116 180533 MAP2K3 fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Signal transduction through IL1R, TNF/Stress Related Signaling, Toll-Like Receptor Pathway 0.0009666 1.561
1454 tollPathway_h BioCarta H003232_01 Info Mitogen-activated protein kinase kinase kinase 14 H003232_01 Y10256 47007 MAP3K14 CD40L Signaling Pathway, Double Stranded RNA Induced Gene Expression, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Keratinocyte Differentiation, MAP Kinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Signal transduction through IL1R, TACI and BCMA stimulation of B cell immune responses., TNF/Stress Related Signaling, TNFR2 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system 0.005309 0.755
1455 tollPathway_h BioCarta H002895_01 Info Mitogen-activated protein kinase 14 H002895_01 L35263 79107 MAPK14 BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAP Kinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm … 0.0086925 1.429
1456 tollPathway_h BioCarta H003611_01 Info Mitogen-activated protein kinase kinase 4 H003611_01 L36870 75217 MAP2K4 Perou’s – Intrinsic – Breast-Cancer-Genes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Ceramide Signaling Pathway, EGF Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, Inhibition of Cellular Proliferation by Gleevec, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , PDGF Signaling Pathway, T Cell Receptor Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system 0.012502 0.753
1457 tollPathway_h BioCarta H003657_01 Info Protein kinase, interferon-inducible double stranded RNA dependent H003657_01 NM_002759 274382 PRKR cell_cycle, cell_signaling, signal_transduction 0.0267646 1.238
1458 tollPathway_h BioCarta H000657_01 Info Myeloid differentiation primary response gene (88) H000657_01 U70451 82116 MYD88 Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Signal transduction through IL1R, Toll-Like Receptor Pathway, apoptosis, immunology, misc 0.0732203 1.23
1459 tollPathway_h BioCarta H003158_01 Info Mitogen-activated protein kinase 8 H003158_01 L26318 190913 MAPK8 Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig … 0.1287835 1.166
1460 tollPathway_h BioCarta H000042_01 Info Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma H000042_01 AF074382 43505 IKBKG CD40L Signaling Pathway, NF-kB Signaling Pathway, TNF/Stress Related Signaling, TNFR2 Signaling Pathway, Toll-Like Receptor Pathway 0.2784213 1.13
1461 tollPathway_h BioCarta H007884_01 Info TOLLIP protein H007884_01 AJ242972 25413 LOC54472 Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Signal transduction through IL1R, Toll-Like Receptor Pathway 0.3826742 0.898
1462 tollPathway_h BioCarta H006851_01 Info TAK1-binding protein 2; KIAA0733 protein H006851_01 AL117407 109727 KIAA0733 Toll-Like Receptor Pathway 0.4908732 1.066
1463 tollPathway_h BioCarta H006060_01 Info ECSIT H006060_01 AF243044 22199 LOC51295 Signal transduction through IL1R, Toll-Like Receptor Pathway 0.525719 1.065
1464 tollPathway_h BioCarta H011421_01 Info Toll-like receptor 3 H011421_01 U88879 29499 TLR3 Toll-Like Receptor Pathway, immunology 0.5596679 1.057
1465 tollPathway_h BioCarta H006116_01 Info MD-2 protein H006116_01 AB018549 69328 MD-2 Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Toll-Like Receptor Pathway 0.661613 1.048
1466 tollPathway_h BioCarta H002447_01 Info Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha H002447_01 M69043 81328 NFKBIA Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Signal transduction through IL1R, T Cell Receptor Signaling Pathway, The 4-1BB-dependent immune … 0.8245205 0.975
1467 tollPathway_h BioCarta H002076_01 Info Interleukin-1 receptor-associated kinase 1 H002076_01 L76191 182018 IRAK1 Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, NF-kB Signaling Pathway, Toll-Like Receptor Pathway, immunology, signal_transduction 0.8472418 0.982
1468 tollPathway_h BioCarta H001376_01 Info Homo sapiens mRNA; cDNA DKFZp566L084 (from clone DKFZp566L084) H001376_01 AL133012 306440 Acetylation and Deacetylation of RelA in The Nucleus, AKT Signaling Pathway, CD40L Signaling Pathway, Double Stranded RNA Induced Gene Expression, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Ras Signaling Pathway, Signal transduction through IL1R, TACI and BCMA stimulation of B cell immune responses., The 4-1BB-dependent immune response, TNF/Stress Related Signaling, TNFR2 Signaling Pathway, Toll-Like Receptor Pathway, cell_cycle, cell_signaling, signal_transduction 0.8639394 0.98
1469 tollPathway_h BioCarta H002350_01 Info Peroxisome proliferative activated receptor, alpha H002350_01 L02932 998 PPARA Basic mechanism of action of PPARa, PPARb(d) and PPARg and effects on gene expression, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Nuclear Receptors in Lipid Metabolism and Toxicity, Regulation of PGC-1a, �-arrestins in GPCR Desensitization, Toll-Like Receptor Pathway 0.8655149 1.015
1470 tollPathway_h BioCarta H003711_01 Info Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) H003711_01 M58603 83428 NFKB1 Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Bone Remodelling, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Ceramide Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Corticosteroids and cardioprotection, CXCR4 Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, Free Radical Induced Apoptosis, HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of a … 0.8665095 1.017
1471 tollPathway_h BioCarta H002963_01 Info V-rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide H002963_01 L19067 75569 RELA Acetylation and Deacetylation of RelA in The Nucleus, Erythropoietin mediated neuroprotection through NF-kB, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, immunology, tsonc 0.9724165 1.003
1472 MAP00240_Pyrimidine_metabolism_h GenMAPP H000616_01 Info Nucleoside phosphorylase H000616_01 X00737 75514 NP Nicotinate and nicotinamide metabolism, Purine metabolism, Pyrimidine metabolism, gene_regulation, immunology, transcription 0.0005739 0.632
1473 MAP00240_Pyrimidine_metabolism_h GenMAPP H002879_01 Info Polymerase (DNA directed), beta H002879_01 D29013 180107 POLB DNA polymerase, Purine metabolism, Pyrimidine metabolism, cell_cycle, DNA_damage, DNA_replication, immunology 0.0052758 0.781
1474 MAP00240_Pyrimidine_metabolism_h GenMAPP H001903_01 Info Polymerase (DNA directed), gamma H001903_01 X98093 80961 POLG DNA polymerase, Purine metabolism, Pyrimidine metabolism 0.0148856 0.783
1475 MAP00240_Pyrimidine_metabolism_h GenMAPP H002569_01 Info Thymidine kinase 1, soluble H002569_01 K02581 105097 TK1 Pyrimidine metabolism, gene_regulation, immunology, pharmacology, transcription 0.0152534 1.253
1476 MAP00240_Pyrimidine_metabolism_h GenMAPP H000456_01 Info Adenylate kinase 3 H000456_01 X60673 274691 AK3 Pyrimidine metabolism, cell_cycle, cell_signaling, signal_transduction 0.0174112 0.738
1477 MAP00240_Pyrimidine_metabolism_h GenMAPP H002908_01 Info Ribonucleotide reductase M1 polypeptide H002908_01 X59543 2934 RRM1 Purine metabolism, Pyrimidine metabolism, immunology, pharmacology 0.0183576 0.781
1478 MAP00240_Pyrimidine_metabolism_h GenMAPP H007908_01 Info Polymerase (RNA) II (DNA directed) polypeptide K (7.0kD) H007908_01 Z47727 150675 POLR2K Purine metabolism, Pyrimidine metabolism, RNA polymerase 0.0188042 0.756
1479 MAP00240_Pyrimidine_metabolism_h GenMAPP H000522_01 Info Cytidine deaminase H000522_01 L27943 72924 CDA Pyrimidine metabolism, immunology, pharmacology 0.0460601 1.313
1480 MAP00240_Pyrimidine_metabolism_h GenMAPP H007101_01 Info Polymerase (RNA) II (DNA directed) polypeptide J (13.3kD) H007101_01 L37127 80475 POLR2J 0.0526802 1.218
1481 MAP00240_Pyrimidine_metabolism_h GenMAPP H003792_01 Info Polymerase (DNA directed), alpha H003792_01 X06745 267289 POLA DNA polymerase, Purine metabolism, Pyrimidine metabolism, DNA_replication 0.072381 0.83
1482 MAP00240_Pyrimidine_metabolism_h GenMAPP H002687_01 Info Ribonucleotide reductase M2 polypeptide H002687_01 X59618 75319 RRM2 Purine metabolism, Pyrimidine metabolism, pharmacology 0.0826808 0.823
1483 MAP00240_Pyrimidine_metabolism_h GenMAPP H011566_01 Info Homo sapiens mutant DNA polymerase beta mRNA, partial CDS H011566_01 S69873 241525 DNA polymerase, Purine metabolism, Pyrimidine metabolism, cell_cycle, DNA_damage, DNA_replication, immunology 0.096998 0.865
1484 MAP00240_Pyrimidine_metabolism_h GenMAPP H002522_01 Info Dihydropyrimidine dehydrogenase H002522_01 U20938 1602 DPYD beta-Alanine metabolism, Pantothenate and CoA biosynthesis, Pyrimidine metabolism, immunology, pharmacology 0.104101 0.85
1485 MAP00240_Pyrimidine_metabolism_h GenMAPP H000394_01 Info Deoxycytidine kinase H000394_01 M60527 709 DCK Purine metabolism, Pyrimidine metabolism, gene_regulation, pharmacology, transcription 0.1931198 0.887
1486 MAP00240_Pyrimidine_metabolism_h GenMAPP H000074_01 Info Polymerase (DNA directed), delta 2, regulatory subunit (50kD) H000074_01 U21090 74598 POLD2 DNA polymerase, Purine metabolism, Pyrimidine metabolism 0.203416 0.871
1487 MAP00240_Pyrimidine_metabolism_h GenMAPP H000658_01 Info Uridine monophosphate synthetase (orotate phosphoribosyl transferase and orotidine-5′-decarboxylase) H000658_01 J03626 2057 UMPS Pyrimidine metabolism, immunology, pharmacology 0.2195884 1.099
1488 MAP00240_Pyrimidine_metabolism_h GenMAPP H000484_01 Info CTP synthase H000484_01 X52142 251871 CTPS Perou’s – Intrinsic – Breast-Cancer-Genes, Pyrimidine metabolism, gene_regulation, transcription 0.2236373 0.879
1489 MAP00240_Pyrimidine_metabolism_h GenMAPP H010908_01 Info Polymerase (RNA) II (DNA directed) polypeptide E (25kD) H010908_01 D38251 24301 POLR2E Purine metabolism, Pyrimidine metabolism, RNA polymerase 0.2811044 1.09
1490 MAP00240_Pyrimidine_metabolism_h GenMAPP H006451_01 Info Polymerase (RNA) II (DNA directed) polypeptide H H006451_01 U37689 3128 POLR2H Purine metabolism, Pyrimidine metabolism, RNA polymerase 0.3071417 0.912
1491 MAP00240_Pyrimidine_metabolism_h GenMAPP H016370_01 Info Polymerase (RNA) II (DNA directed) polypeptide I (14.5kD) H016370_01 NM_006233 47062 POLR2I Purine metabolism, Pyrimidine metabolism, RNA polymerase 0.3118426 1.12
1492 MAP00240_Pyrimidine_metabolism_h GenMAPP H007868_01 Info Similar to DNA-directed RNA polymerase I (135 kDa) H007868_01 AK001678 86337 FLJ10816 Purine metabolism, Pyrimidine metabolism, RNA polymerase 0.3875312 1.072
1493 MAP00240_Pyrimidine_metabolism_h GenMAPP H005570_01 Info Polymerase (RNA) II (DNA directed) polypeptide B (140kD) H005570_01 X63563 296014 POLR2B Purine metabolism, Pyrimidine metabolism, RNA polymerase 0.4005386 0.927
1494 MAP00240_Pyrimidine_metabolism_h GenMAPP H008768_01 Info Polymerase (RNA) II (DNA directed) polypeptide A (220kD) H008768_01 X63564 171880 POLR2A CARM1 and Regulation of the Estrogen Receptor, Chromatin Remodeling by hSWI/SNF ATP-dependent Complexes, Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells, Repression of Pain Sensation by the Transcriptional Regulator DREAM, Telomeres, Telomerase, Cellular Aging, and Immortality, The information-processing pathway at the IFN-beta enhancer, Purine metabolism, Pyrimidine metabolism, RNA polymerase 0.4709936 0.933
1495 MAP00240_Pyrimidine_metabolism_h GenMAPP H006464_01 Info Polymerase (RNA) II (DNA directed) polypeptide L (7.6kD) H006464_01 U37690 71618 POLR2L Purine metabolism, Pyrimidine metabolism, RNA polymerase 0.5110537 0.933
1496 MAP00240_Pyrimidine_metabolism_h GenMAPP H008686_01 Info DUTP pyrophosphatase H008686_01 U31930 82113 DUT Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Pyrimidine metabolism, gene_regulation, transcription 0.6087897 1.051
1497 MAP00240_Pyrimidine_metabolism_h GenMAPP H002572_01 Info Non-metastatic cells 2, protein (NM23B) expressed in H002572_01 M36981 275163 NME2 cell_cycle, cell_signaling, signal_transduction 0.6557968 0.941
1498 MAP00240_Pyrimidine_metabolism_h GenMAPP H002195_01 Info Non-metastatic cells 1, protein (NM23A) expressed in H002195_01 X17620 118638 NME1 Endocytotic role of NDK, Phosphins and Dynamin, Granzyme A mediated Apoptosis Pathway, Purine metabolism, Pyrimidine metabolism, cell_cycle, cell_signaling, immunology, signal_transduction, tsonc 0.6910793 0.967
1499 MAP00240_Pyrimidine_metabolism_h GenMAPP H002094_01 Info Thymidylate synthetase H002094_01 X02308 82962 TYMS One carbon pool by folate, Pyrimidine metabolism, metabolism, pharmacology 0.6945693 1.041
1500 MAP00240_Pyrimidine_metabolism_h GenMAPP H007289_01 Info Insulin-like growth factor binding protein 7 H007289_01 S75725 119206 IGFBP7 0.80895 1.034
1501 g2Pathway_h BioCarta H000208_01 Info Breast cancer 1, early onset H000208_01 NM_007295 194143 BRCA1 ATM Signaling Pathway, BRCA1-dependent Ub-ligase activity, CARM1 and Regulation of the Estrogen Receptor, Cell Cycle: G2/M Checkpoint, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, DNA_damage, immunology, tsonc 0.009032 0.746
1502 g2Pathway_h BioCarta H002092_01 Info Ataxia telangiectasia and Rad3 related H002092_01 U49844 77613 ATR Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Regulation of cell cycle progression by Plk3, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, Phosphatidylinositol signaling system, DNA_replication, immunology 0.0105491 0.753
1503 g2Pathway_h BioCarta H002890_01 Info Ribosomal protein S6 kinase, 90kD, polypeptide 1 H002890_01 L07597 149957 RPS6KA1 Cell Cycle: G2/M Checkpoint, Erk1/Erk2 Mapk Signaling pathway, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, MAP Kinase Signaling Pathway, Melanocyte Development and Pigmentation Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of BAD phosphorylation, Role of Erk5 in Neuronal Survival, Transcription factor CREB and its extracellular signals, Phosphatidylinositol signaling system 0.0138896 1.42
1504 g2Pathway_h BioCarta H001323_01 Info Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide H001323_01 X56468 74405 YWHAQ Cell Cycle: G2/M Checkpoint 0.0151437 0.755
1505 g2Pathway_h BioCarta H002304_01 Info Cell division cycle 25B H002304_01 S78187 153752 CDC25B 0.0167858 0.8
1506 g2Pathway_h BioCarta H003739_01 Info Cell division cycle 2, G1 to S and G2 to M H003739_01 X05360 184572 CDC2 Activation of Src by Protein-tyrosine phosphatase alpha, AKAP95 role in mitosis and chromosome dynamics, cdc25 and chk1 Regulatory Pathway in response to DNA damage, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, How Progesterone Initiates the Oocyte Maturation, Protein Kinase A at the Centrosome, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of Splicing through Sam68, Sonic Hedgehog (SHH) Receptor Ptc1 Regulates cell cycle, Stathmin and breast cancer resistance to antimicrotubule agents, Phosphatidylinositol signaling system, cell_cycle 0.0222229 0.733
1507 g2Pathway_h BioCarta H002789_01 Info Tumor protein p53 (Li-Fraumeni syndrome) H002789_01 NM_000546 1846 TP53 Apoptotic Signaling in Response to DNA Damage, ATM Signaling Pathway, BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Chaperones modulate interferon Signaling Pathway, CTCF: First Multivalent Nuclear Factor, Double Stranded RNA Induced Gene Expression, Estrogen-responsive protein Efp controls cell cycle and breast tumors growth, Hypoxia and p53 in the Cardiovascular system, Overview of telomerase protein component gene hTert Transcriptional Regulation , p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of cell cycle progression by Plk3, Regulation of transcriptional activity by PML, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, DNA_damage, gene_regulation, immunology, transcription, tsonc 0.0273242 1.207
1508 g2Pathway_h BioCarta H003759_01 Info Cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) H003759_01 U40343 29656 CDKN2D Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation 0.0311312 1.253
1509 g2Pathway_h BioCarta H002149_01 Info Cyclin-dependent kinase inhibitor 1A (p21, Cip1) H002149_01 U03106 179665 CDKN1A ATM Signaling Pathway, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, Effects of calcineurin in Keratinocyte Differentiation, Erythropoietin mediated neuroprotection through NF-kB, Hypoxia and p53 in the Cardiovascular system, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, immunology, tsonc 0.0349766 1.236
1510 g2Pathway_h BioCarta H002371_01 Info Cyclin B1 H002371_01 M25753 23960 CCNB1 Activation of Src by Protein-tyrosine phosphatase alpha, AKAP95 role in mitosis and chromosome dynamics, Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, How Progesterone Initiates the Oocyte Maturation, Sonic Hedgehog (SHH) Receptor Ptc1 Regulates cell cycle, Stathmin and breast cancer resistance to antimicrotubule agents, cell_cycle 0.037756 0.797
1511 g2Pathway_h BioCarta H003048_01 Info Cell division cycle 25C H003048_01 M34065 656 CDC25C How Progesterone Initiates the Oocyte Maturation, Regulation of cell cycle progression by Plk3, cell_cycle, cell_signaling 0.1856754 1.116
1512 g2Pathway_h BioCarta H007143_01 Info Hypothetical protein FLJ10883 H007143_01 AB028973 184628 FLJ10883 cdc25 and chk1 Regulatory Pathway in response to DNA damage, Cell Cycle: G2/M Checkpoint, How Progesterone Initiates the Oocyte Maturation, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage 0.2391265 0.908
1513 g2Pathway_h BioCarta H008573_01 Info Myelin transcription factor 1 H008573_01 M96980 279562 MYT1 cdc25 and chk1 Regulatory Pathway in response to DNA damage, Cell Cycle: G2/M Checkpoint, How Progesterone Initiates the Oocyte Maturation, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage 0.3193113 1.107
1514 g2Pathway_h BioCarta H003351_01 Info Protein kinase, DNA-activated, catalytic polypeptide H003351_01 U47077 155637 PRKDC Cell Cycle: G2/M Checkpoint, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, TNFR1 Signaling Pathway, Phosphatidylinositol signaling system, DNA_damage, immunology 0.3847336 0.919
1515 g2Pathway_h BioCarta H002782_01 Info Wee1+ (S. pombe) homolog H002782_01 X62048 75188 WEE1 cdc25 and chk1 Regulatory Pathway in response to DNA damage, Cell Cycle: G2/M Checkpoint, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, immunology 0.4033875 1.142
1516 g2Pathway_h BioCarta H003766_01 Info Mouse double minute 2, human homolog of; p53-binding protein H003766_01 M92424 170027 MDM2 ATM Signaling Pathway, Cell Cycle: G2/M Checkpoint, CTCF: First Multivalent Nuclear Factor, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, p53 Signaling Pathway, Sumoylation by RanBP2 Regulates Transcriptional Repression, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, gene_regulation, transcription, tsonc 0.8018001 0.978
1517 g2Pathway_h BioCarta H002232_01 Info Cell division cycle 34 H002232_01 L22005 76932 CDC34 Cell Cycle: G2/M Checkpoint, Cyclin E Destruction Pathway, E2F1 Destruction Pathway, Ubiquitin mediated proteolysis 0.8799021 0.983
1518 g2Pathway_h BioCarta H003151_01 Info E1A binding protein p300 H003151_01 U01877 25272 EP300 Acetylation and Deacetylation of RelA in The Nucleus, CARM1 and Regulation of the Estrogen Receptor, Cell Cycle: G2/M Checkpoint, Control of Gene Expression by Vitamin D Receptor, Hypoxia and p53 in the Cardiovascular system, Hypoxia-Inducible Factor in the Cardiovascular System, IL-7 Signal Transduction, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Melanocyte Development and Pigmentation Pathway, Multi-step Regulation of Transcription by Pitx2, NFkB activation by Nontypeable Hemophilus influenzae, Pelp1 Modulation of Estrogen Receptor Activity, Role of ERBB2 in Signal Transduction and Oncology, Role of MEF2D in T-cell Apoptosis, Role of PPAR-gamma Coactivators in Obesity and Thermogenesis, TGF beta signaling pathway, Transcription Regulation by Methyltransferase of CARM1, gene_regulation, transcription 0.9607239 1.004
1519 gabaPathway_h BioCarta H007996_01 Info GABA(A) receptor-associated protein H007996_01 NM_007278 7719 GABARAP Gamma-aminobutyric Acid Receptor Life Cycle 0.0021636 1.497
1520 gabaPathway_h BioCarta H001660_01 Info Dynamin 1 H001660_01 L07807 166161 DNM1 Endocytotic role of NDK, Phosphins and Dynamin, Gamma-aminobutyric Acid Receptor Life Cycle, Role of �-arrestins in the activation and targeting of MAP kinases, Roles of �-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling, �-arrestins in GPCR Desensitization 0.0631163 0.822
1521 gabaPathway_h BioCarta H001124_01 Info Gamma-aminobutyric acid (GABA) A receptor, alpha 1 H001124_01 NM_000806 45740 GABRA1 0.4106398 0.915
1522 gabaPathway_h BioCarta H005952_01 Info Gephyrin H005952_01 AB037806 13405 GPHN Gamma-aminobutyric Acid Receptor Life Cycle 0.633937 0.932
1523 gabaPathway_h BioCarta H002383_01 Info Gamma-aminobutyric acid (GABA) A receptor, alpha 3 H002383_01 S62908 123024 GABRA3 Cardiac Protection Against ROS , Gamma-aminobutyric Acid Receptor Life Cycle 0.853131 0.98
1524 keratinocytePathway_h BioCarta H002040_01 Info Epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog) H002040_01 X00588 77432 EGFR Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Keratinocyte Differentiation, Map Kinase Inactivation of SMRT Corepressor, mCalpain and friends in Cell motility, Neuroregulin receptor degradation protein-1 Controls ErbB3 receptor recycling, Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Role of ERBB2 in Signal Transduction and Oncology, Sprouty regulation of tyrosine kinase signals, Telomeres, Telomerase, Cellular Aging, and Immortality, The role of FYVE-finger proteins in vesicle transport, Trefoil Factors Initiate Mucosal Healing, angiogenesis, signal_transduction, tsonc 0.0004362 0.669
1525 keratinocytePathway_h BioCarta H003200_01 Info Mitogen-activated protein kinase kinase 3 H003200_01 D87116 180533 MAP2K3 fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Signal transduction through IL1R, TNF/Stress Related Signaling, Toll-Like Receptor Pathway 0.0009666 1.561
1526 keratinocytePathway_h BioCarta H003232_01 Info Mitogen-activated protein kinase kinase kinase 14 H003232_01 Y10256 47007 MAP3K14 CD40L Signaling Pathway, Double Stranded RNA Induced Gene Expression, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Keratinocyte Differentiation, MAP Kinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Signal transduction through IL1R, TACI and BCMA stimulation of B cell immune responses., TNF/Stress Related Signaling, TNFR2 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system 0.005309 0.755
1527 keratinocytePathway_h BioCarta H002893_01 Info V-raf-1 murine leukemia viral oncogene homolog 1 H002893_01 X03484 85181 RAF1 Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … 0.0062484 1.596
1528 keratinocytePathway_h BioCarta H002895_01 Info Mitogen-activated protein kinase 14 H002895_01 L35263 79107 MAPK14 BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAP Kinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm … 0.0086925 1.429
1529 keratinocytePathway_h BioCarta H003611_01 Info Mitogen-activated protein kinase kinase 4 H003611_01 L36870 75217 MAP2K4 Perou’s – Intrinsic – Breast-Cancer-Genes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Ceramide Signaling Pathway, EGF Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, Inhibition of Cellular Proliferation by Gleevec, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , PDGF Signaling Pathway, T Cell Receptor Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system 0.012502 0.753
1530 keratinocytePathway_h BioCarta H001365_01 Info Protein kinase C, beta 1 H001365_01 X07109 77202 PRKCB1 Bioactive Peptide Induced Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Ion Channel and Phorbol Esters Signaling Pathway, T Cell Receptor Signaling Pathway, Phosphatidylinositol signaling system, angiogenesis, cell_cycle, cell_signaling, signal_transduction 0.0304335 1.379
1531 keratinocytePathway_h BioCarta H003259_01 Info Sp1 transcription factor H003259_01 J03133 2021 SP1 Agrin in Postsynaptic Differentiation, Effects of calcineurin in Keratinocyte Differentiation, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase protein component gene hTert Transcriptional Regulation , Overview of telomerase RNA component gene hTerc Transcriptional Regulation 0.0557417 0.814
1532 keratinocytePathway_h BioCarta H003107_01 Info Mitogen-activated protein kinase 13 H003107_01 AF004709 178695 MAPK13 Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Stathmin and breast cancer resistance to antimicrotubule agents, Phosphatidylinositol signaling system 0.0717244 1.171
1533 keratinocytePathway_h BioCarta H002049_01 Info Death-associated protein 6 H002049_01 AB015051 180224 DAXX FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , Regulation of transcriptional activity by PML, Stress Induction of HSP Regulation, apoptosis 0.0788021 1.159
1534 keratinocytePathway_h BioCarta H002906_01 Info Protein kinase C, eta H002906_01 M55284 315366 PRKCH 0.0889748 0.857
1535 keratinocytePathway_h BioCarta H003178_01 Info Mitogen-activated protein kinase 3 H003178_01 X60188 861 MAPK3 Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … 0.0986041 1.184
1536 keratinocytePathway_h BioCarta H002506_01 Info Tumor necrosis factor receptor superfamily, member 1B H002506_01 M32315 256278 TNFRSF1B TNFR2 Signaling Pathway, immunology 0.1166754 1.17
1537 keratinocytePathway_h BioCarta H003158_01 Info Mitogen-activated protein kinase 8 H003158_01 L26318 190913 MAPK8 Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig … 0.1287835 1.166
1538 keratinocytePathway_h BioCarta H002238_01 Info Protein kinase C, delta H002238_01 D10495 155342 PRKCD HIV-I Nef: negative effector of Fas and TNF 0.1330434 1.177
1539 keratinocytePathway_h BioCarta H003249_01 Info V-ets avian erythroblastosis virus E26 oncogene homolog 1 H003249_01 X14798 248109 ETS1 Keratinocyte Differentiation, METS affect on Macrophage Differentiation, tsonc 0.1428371 0.878
1540 keratinocytePathway_h BioCarta H003309_01 Info Mitogen-activated protein kinase kinase 7 H003309_01 AF013589 110299 MAP2K7 Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Keratinocyte Differentiation, MAP Kinase Signaling Pathway 0.3044184 1.088
1541 keratinocytePathway_h BioCarta H003644_01 Info Tumor necrosis factor receptor superfamily, member 6 H003644_01 X63717 82359 TNFRSF6 apoptosis, immunology 0.4621499 0.927
1542 keratinocytePathway_h BioCarta H002340_01 Info Mitogen-activated protein kinase kinase kinase 5 H002340_01 U67156 151988 MAP3K5 HIV-I Nef: negative effector of Fas and TNF, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , The 4-1BB-dependent immune response 0.5393151 1.07
1543 keratinocytePathway_h BioCarta H002722_01 Info Mitogen-activated protein kinase kinase 1 H002722_01 L11284 3446 MAP2K1 Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … 0.7377933 0.973
1544 keratinocytePathway_h BioCarta H001681_01 Info Protein kinase C, theta H001681_01 L01087 211593 PRKCQ Keratinocyte Differentiation, cell_cycle, cell_signaling, immunology, signal_transduction 0.8037373 1.019
1545 keratinocytePathway_h BioCarta H002447_01 Info Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha H002447_01 M69043 81328 NFKBIA Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Signal transduction through IL1R, T Cell Receptor Signaling Pathway, The 4-1BB-dependent immune … 0.8245205 0.975
1546 keratinocytePathway_h BioCarta H001596_01 Info Protein kinase C, gamma H001596_01 Z15114 2890 PRKCG Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.8498034 1.018
1547 keratinocytePathway_h BioCarta H001376_01 Info Homo sapiens mRNA; cDNA DKFZp566L084 (from clone DKFZp566L084) H001376_01 AL133012 306440 Acetylation and Deacetylation of RelA in The Nucleus, AKT Signaling Pathway, CD40L Signaling Pathway, Double Stranded RNA Induced Gene Expression, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Ras Signaling Pathway, Signal transduction through IL1R, TACI and BCMA stimulation of B cell immune responses., The 4-1BB-dependent immune response, TNF/Stress Related Signaling, TNFR2 Signaling Pathway, Toll-Like Receptor Pathway, cell_cycle, cell_signaling, signal_transduction 0.8639394 0.98
1548 keratinocytePathway_h BioCarta H003711_01 Info Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) H003711_01 M58603 83428 NFKB1 Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Bone Remodelling, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Ceramide Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Corticosteroids and cardioprotection, CXCR4 Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, Free Radical Induced Apoptosis, HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of a … 0.8665095 1.017
1549 keratinocytePathway_h BioCarta H002963_01 Info V-rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide H002963_01 L19067 75569 RELA Acetylation and Deacetylation of RelA in The Nucleus, Erythropoietin mediated neuroprotection through NF-kB, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, immunology, tsonc 0.9724165 1.003
1550 lairPathway_h BioCarta H003139_01 Info Integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 H003139_01 M15395 83968 ITGB2 Adhesion and Diapedesis of Granulocytes, Adhesion and Diapedesis of Lymphocytes, Adhesion Molecules on Lymphocyte, B Lymphocyte Cell Surface Molecules, Cells and Molecules involved in local acute inflammatory response, CTL mediated immune response against target cells , Monocyte and its Surface Molecules, Neutrophil and Its Surface Molecules, T Cytotoxic Cell Surface Molecules, T Helper Cell Surface Molecules, cell_signaling, immunology, metastasis 0.0091308 1.578
1551 lairPathway_h BioCarta H002944_01 Info Interleukin 8 H002944_01 M17017 624 IL8 Adhesion and Diapedesis of Granulocytes, Adhesion and Diapedesis of Lymphocytes, Cells and Molecules involved in local acute inflammatory response, Cytokine Network, Cytokines and Inflammatory Response, Free Radical Induced Apoptosis, IL 17 Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Proepithelin Conversion to Epithelin and Wound Repair Control, Regulation of hematopoiesis by cytokines, immunology 0.0100881 0.681
1552 lairPathway_h BioCarta H002233_01 Info Selectin P ligand H002233_01 NM_003006 79283 SELPLG Adhesion and Diapedesis of Granulocytes, Cells and Molecules involved in local acute inflammatory response, angiogenesis, immunology, metastasis 0.0126025 1.69
1553 lairPathway_h BioCarta H002526_01 Info Complement component 5 H002526_01 M57729 1281 C5 Adhesion and Diapedesis of Granulocytes, Alternative Complement Pathway, Cells and Molecules involved in local acute inflammatory response, Classical Complement Pathway, Complement Pathway, Lectin Induced Complement Pathway, immunology, misc 0.245454 0.865
1554 lairPathway_h BioCarta H003794_01 Info Selectin P (granule membrane protein 140kD, antigen CD62) H003794_01 NM_003005 73800 SELP Adhesion and Diapedesis of Granulocytes, Cells and Molecules involved in local acute inflammatory response, Eph Kinases and ephrins support platelet aggregation, Monocyte and its Surface Molecules, cell_signaling, immunology, metastasis 0.3754462 1.081
1555 lairPathway_h BioCarta H003784_01 Info Intercellular adhesion molecule 1 (CD54), human rhinovirus receptor H003784_01 M24283 168383 ICAM1 Adhesion and Diapedesis of Granulocytes, Adhesion and Diapedesis of Lymphocytes, Adhesion Molecules on Lymphocyte, B Lymphocyte Cell Surface Molecules, Cells and Molecules involved in local acute inflammatory response, CTL mediated immune response against target cells , Monocyte and its Surface Molecules, Neutrophil and Its Surface Molecules, T Cytotoxic Cell Surface Molecules, T Helper Cell Surface Molecules, cell_signaling, immunology, metastasis 0.4642919 0.93
1556 lairPathway_h BioCarta H002469_01 Info Complement component 3 H002469_01 K02765 284394 C3 Alternative Complement Pathway, Cells and Molecules involved in local acute inflammatory response, Classical Complement Pathway, Complement Pathway, Lectin Induced Complement Pathway, immunology 0.6788808 1.044
1557 lairPathway_h BioCarta H003110_01 Info Interleukin 6 (interferon, beta 2) H003110_01 X04430 93913 IL6 Cells and Molecules involved in local acute inflammatory response, Cytokine Network, Cytokines and Inflammatory Response, Erythrocyte Differentiation Pathway, IL 17 Signaling Pathway, IL 5 Signaling Pathway, IL 6 signaling pathway, IL-10 Anti-inflammatory Signaling Pathway, Low-density lipoprotein (LDL) pathway during atherogenesis, Regulation of hematopoiesis by cytokines, Role of ERBB2 in Signal Transduction and Oncology, Signal transduction through IL1R, immunology 0.680804 1.036
1558 lairPathway_h BioCarta H003724_01 Info integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) H003724_01 NM_002211 202661 ITGB1 Adhesion and Diapedesis of Lymphocytes, Adhesion Molecules on Lymphocyte, Agrin in Postsynaptic Differentiation, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, B Cell Survival Pathway, Cells and Molecules involved in local acute inflammatory response, Eph Kinases and ephrins support platelet aggregation, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Integrin Signaling Pathway, mCalpain and friends in Cell motility, Monocyte and its Surface Molecules, PTEN dependent cell cycle arrest and apoptosis, Ras-Independent pathway in NK cell-mediated cytotoxicity, Signaling of Hepatocyte Growth Factor Receptor, Trefoil Factors Initiate Mucosal Healing, uCalpain and friends in Cell spread, cell_signaling, immunology, metastasis 0.9378203 0.993
1559 MAP00030_Pentose_phosphate_pathway_h GenMAPP H004823_01 Info Aldolase C, fructose-bisphosphate H004823_01 AF054987 155247 ALDOC Carbon fixation, Fructose and mannose metabolism, Glycolysis / Gluconeogenesis, Inositol metabolism, Pentose phosphate pathway 0.001576 0.707
1560 MAP00030_Pentose_phosphate_pathway_h GenMAPP H003374_01 Info Aldolase A, fructose-bisphosphate H003374_01 M11560 273415 ALDOA Downregulated of MTA-3 in ER-negative Breast Tumors, Carbon fixation, Fructose and mannose metabolism, Glycolysis / Gluconeogenesis, Inositol metabolism, Pentose phosphate pathway, immunology 0.0300936 1.252
1561 MAP00030_Pentose_phosphate_pathway_h GenMAPP H005517_01 Info Transaldolase 1 H005517_01 NM_006755 77290 TALDO1 Pentose phosphate pathway 0.097425 1.207
1562 MAP00030_Pentose_phosphate_pathway_h GenMAPP H001387_01 Info Phosphofructokinase, platelet H001387_01 D25328 99910 PFKP Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Pentose phosphate pathway, immunology 0.101431 0.866
1563 MAP00030_Pentose_phosphate_pathway_h GenMAPP H002248_01 Info Glucose-6-phosphate dehydrogenase H002248_01 X03674 80206 G6PD Glutathione metabolism, Pentose phosphate pathway, immunology 0.1773825 0.891
1564 MAP00030_Pentose_phosphate_pathway_h GenMAPP H005470_01 Info Homo sapiens mRNA; cDNA DKFZp762B245 (from clone DKFZp762B245); partial CDS H005470_01 AL162062 198182 0.1944956 1.125
1565 MAP00030_Pentose_phosphate_pathway_h GenMAPP H001378_01 Info Phosphofructokinase, muscle H001378_01 U24183 75160 PFKM Phosphoinositides and their downstream targets., Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Pentose phosphate pathway, immunology 0.2927445 0.908
1566 MAP00030_Pentose_phosphate_pathway_h GenMAPP H000502_01 Info Phosphoribosyl pyrophosphate synthetase 1 H000502_01 D00860 56 PRPS1 Histidine metabolism, Pentose phosphate pathway, Purine metabolism, gene_regulation, transcription 0.3045664 0.909
1567 MAP00030_Pentose_phosphate_pathway_h GenMAPP H001548_01 Info Phosphogluconate dehydrogenase H001548_01 U30255 75888 PGD Pentose phosphate pathway, immunology 0.3414801 1.107
1568 MAP00030_Pentose_phosphate_pathway_h GenMAPP H003868_01 Info Hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) H003868_01 AJ012590 194728 H6PD Pentose phosphate pathway 0.4449595 0.923
1569 MAP00030_Pentose_phosphate_pathway_h GenMAPP H001385_01 Info Phosphofructokinase, liver H001385_01 X15573 155455 PFKL Glycolysis Pathway, Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Pentose phosphate pathway, immunology 0.9581627 1.005
1570 ANDROGEN_UP_GENES_h na H001845_01 Info Spermidine/spermine N1-acetyltransferase H001845_01 AL050290 28491 SAT Perou’s – Intrinsic – Breast-Cancer-Genes, Arginine and proline metabolism 0.0010835 1.431
1571 ANDROGEN_UP_GENES_h na H010168_01 Info SEC24 (S. cerevisiae) related gene family, member D H010168_01 AB018298 19822 SEC24D 0.0012977 0.668
1572 ANDROGEN_UP_GENES_h na H005263_01 Info Kruppel-like factor 4 (gut) H005263_01 U70663 7934 KLF4 0.0051337 1.303
1573 ANDROGEN_UP_GENES_h na H001207_01 Info Cell membrane glycoprotein, 110000M(r) (surface antigen) H001207_01 D64154 90107 GP110 Perou’s – Intrinsic – Breast-Cancer-Genes 0.0054987 0.761
1574 ANDROGEN_UP_GENES_h na H003576_01 Info Protein tyrosine phosphatase, non-receptor type 21 H003576_01 X79510 155693 PTPN21 0.0156683 0.71
1575 ANDROGEN_UP_GENES_h na H002780_01 Info Actinin, alpha 1 H002780_01 M95178 119000 ACTN1 0.0181707 0.767
1576 ANDROGEN_UP_GENES_h na H003902_01 Info Seladin-1 H003902_01 D13643 75616 KIAA0018 0.0276493 1.192
1577 ANDROGEN_UP_GENES_h na H001749_01 Info Diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein) H001749_01 M14200 78888 DBI 0.0383862 1.259
1578 ANDROGEN_UP_GENES_h na H003086_01 Info Lectin, mannose-binding, 1 H003086_01 X71661 287912 LMAN1 immunology 0.0472878 1.215
1579 ANDROGEN_UP_GENES_h na H001028_01 Info Alpha-2-glycoprotein 1, zinc H001028_01 X59766 71 AZGP1 immunology 0.0695461 0.839
1580 ANDROGEN_UP_GENES_h na H006601_01 Info V-maf musculoaponeurotic fibrosarcoma (avian) oncogene homolog H006601_01 AF055376 30250 MAF GATA3 participate in activating the Th2 cytokine genes expression, tsonc 0.079493 0.812
1581 ANDROGEN_UP_GENES_h na H000736_01 Info 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) H000736_01 X66435 77910 HMGCS1 SREBP control of lipid synthesis, Butanoate metabolism, Synthesis and degradation of ketone bodies, Valine, leucine and isoleucine degradation 0.0809163 0.84
1582 ANDROGEN_UP_GENES_h na H004099_01 Info Phosphatidic acid phosphatase type 2A H004099_01 AF014403 41569 PPAP2A Glycerolipid metabolism, Glycerophospholipid metabolism, Glycosphingolipid metabolism 0.0934873 0.851
1583 ANDROGEN_UP_GENES_h na H001575_01 Info UDP-glucose dehydrogenase H001575_01 AF061016 28309 UGDH Nucleotide sugars metabolism, Pentose and glucuronate interconversions, Starch and sucrose metabolism, immunology 0.1026426 0.854
1584 ANDROGEN_UP_GENES_h na H001158_01 Info UDP-Gal:beta GlcNAc beta 1,4- galactosyltransferase, polypeptide 1 H001158_01 D29805 198248 B4GALT1 Perou’s – Intrinsic – Breast-Cancer-Genes, Galactose metabolism, Keratan sulfate biosynthesis, N-Glycan biosynthesis 0.1752304 1.141
1585 ANDROGEN_UP_GENES_h na H012626_01 Info Beta-2-microglobulin H012626_01 AB021288 75415 B2M Antigen Processing and Presentation, CTL mediated immune response against target cells , Ras-Independent pathway in NK cell-mediated cytotoxicity, immunology 0.1923361 1.156
1586 ANDROGEN_UP_GENES_h na H005886_01 Info Tumor protein D52 H005886_01 U18914 2384 TPD52 0.2657411 0.9
1587 ANDROGEN_UP_GENES_h na H000256_01 Info IQ motif containing GTPase activating protein 2 H000256_01 U51903 78993 IQGAP2 0.2689376 0.912
1588 ANDROGEN_UP_GENES_h na H001535_01 Info Sorbitol dehydrogenase H001535_01 L29008 878 SORD Fructose and mannose metabolism, metabolism 0.3484797 1.082
1589 ANDROGEN_UP_GENES_h na H000577_01 Info Keratin 19 H000577_01 Y00503 182265 KRT19 0.3887528 0.905
1590 ANDROGEN_UP_GENES_h na H006429_01 Info Spermine synthase H006429_01 AD001528 89718 SMS Arginine and proline metabolism, beta-Alanine metabolism, Urea cycle and metabolism of amino groups 0.475118 1.081
1591 ANDROGEN_UP_GENES_h na H004814_01 Info N-myc downstream regulated H004814_01 D87953 75789 NDRG1 0.5742952 1.047
1592 ANDROGEN_UP_GENES_h na H009428_01 Info Stearoyl-CoA desaturase (delta-9-desaturase) H009428_01 AB032261 119597 SCD 0.6120428 0.959
1593 ANDROGEN_UP_GENES_h na H004696_01 Info Calcium/calmodulin-dependent protein kinase kinase 2, beta H004696_01 AB018330 108708 CAMKK2 Ca++/ Calmodulin-dependent Protein Kinase Activation, Phosphatidylinositol signaling system 0.6902672 0.947
1594 ANDROGEN_UP_GENES_h na H007232_01 Info Ankylosis, progressive (mouse) homolog H007232_01 AK001799 168640 ANKH 0.7291801 1.03
1595 ANDROGEN_UP_GENES_h na H005249_01 Info Homo sapiens 10q21 mRNA sequence H005249_01 AF198444 279024 Arginine and proline metabolism, Ascorbate and aldarate metabolism, beta-Alanine metabolism, Bile acid biosynthesis, Butanoate metabolism, Fatty acid metabolism, Glycerolipid metabolism, Glycolysis / Gluconeogenesis, Histidine metabolism, Limonene and pinene degradation, Lysine degradation, Phenylalanine metabolism, Propanoate metabolism, Pyruvate metabolism, Tryptophan metabolism, Tyrosine metabolism, Valine, leucine and isoleucine degradation 0.761598 0.965
1596 ANDROGEN_UP_GENES_h na H004975_01 Info RNA binding motif protein 10 H004975_01 AL137421 154583 RBM10 0.7811927 0.971
1597 ANDROGEN_UP_GENES_h na H000721_01 Info Isopentenyl-diphosphate delta isomerase H000721_01 X17025 76038 IDI1 Biosynthesis of steroids, Terpenoid biosynthesis 0.8096306 0.973
1598 ANDROGEN_UP_GENES_h na H002975_01 Info Leukemia inhibitory factor receptor H002975_01 NM_002310 2798 LIFR immunology 0.8467409 1.028
1599 ANDROGEN_UP_GENES_h na H003522_01 Info Glutathione reductase H003522_01 AF228704 121524 GSR Free Radical Induced Apoptosis, Glutamate metabolism, Glutathione metabolism, immunology, pharmacology 0.906259 1.012
1600 ANDROGEN_UP_GENES_h na H000269_01 Info LIM protein (similar to rat protein kinase C-binding enigma) H000269_01 AF061258 154103 LIM 0.9813357 1.002
1601 ANDROGEN_UP_GENES_h na H000425_01 Info C-mer proto-oncogene tyrosine kinase H000425_01 U08023 306178 MERTK 0.9915103 1.001
1602 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H000732_01 Info Insulin receptor substrate 1 H000732_01 S62539 96063 IRS1 Perou’s – Intrinsic – Breast-Cancer-Genes, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Insulin Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of eIF4e and p70 S6 Kinase, immunology 0.0013348 0.643
1603 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H002055_01 Info Growth factor receptor-bound protein 2 H002055_01 M96995 296381 GRB2 Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel … 0.0022348 1.459
1604 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H002893_01 Info V-raf-1 murine leukemia viral oncogene homolog 1 H002893_01 X03484 85181 RAF1 Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … 0.0062484 1.596
1605 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H002890_01 Info Ribosomal protein S6 kinase, 90kD, polypeptide 1 H002890_01 L07597 149957 RPS6KA1 Cell Cycle: G2/M Checkpoint, Erk1/Erk2 Mapk Signaling pathway, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, MAP Kinase Signaling Pathway, Melanocyte Development and Pigmentation Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of BAD phosphorylation, Role of Erk5 in Neuronal Survival, Transcription factor CREB and its extracellular signals, Phosphatidylinositol signaling system 0.0138896 1.42
1606 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H001323_01 Info Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide H001323_01 X56468 74405 YWHAQ Cell Cycle: G2/M Checkpoint 0.0151437 0.755
1607 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H003305_01 Info Ribosomal protein S6 kinase, 70kD, polypeptide 1 H003305_01 M60724 86858 RPS6KB1 CTCF: First Multivalent Nuclear Factor, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, MAP Kinase Signaling Pathway, mTOR Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Rac 1 cell motility signaling pathway, Regulation of eIF4e and p70 S6 Kinase, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.0214523 1.448
1608 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H003410_01 Info Cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) H003410_01 U26727 1174 CDKN2A Cell Cycle: G1/S Check Point , CTCF: First Multivalent Nuclear Factor, Cyclins and Cell Cycle Regulation, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, immunology, tsonc 0.0245577 0.782
1609 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H001348_01 Info Phosphoinositide-3-kinase, catalytic, delta polypeptide H001348_01 U86453 162808 PIK3CD Inositol phosphate metabolism, Phosphatidylinositol signaling system 0.0324563 1.426
1610 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H000612_01 Info Ribosomal protein S6 kinase, 90kD, polypeptide 3 H000612_01 U08316 173965 RPS6KA3 MAP Kinase Signaling Pathway, Signaling Pathway from G-Protein Families, Phosphatidylinositol signaling system 0.0473043 0.79
1611 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H016134_01 Info V-akt murine thymoma viral oncogene homolog 2 H016134_01 NM_001626 326445 AKT2 Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction, tsonc 0.0530988 1.287
1612 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H014573_01 Info Homo sapiens HSPC106 mRNA, partial CDS H014573_01 AF161369 187763 How Progesterone Initiates the Oocyte Maturation 0.0559133 0.793
1613 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H000521_01 Info Ribosomal protein S6 kinase, 90kD, polypeptide 2 H000521_01 X85106 301664 RPS6KA2 MAP Kinase Signaling Pathway, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.0604408 1.207
1614 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H003178_01 Info Mitogen-activated protein kinase 3 H003178_01 X60188 861 MAPK3 Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … 0.0986041 1.184
1615 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H002508_01 Info Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide H002508_01 M86400 75103 YWHAZ 0.153375 1.146
1616 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H005908_01 Info Flotillin 2 H005908_01 M60922 184488 FLOT2 Perou’s – Intrinsic – Breast-Cancer-Genes 0.179195 1.18
1617 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H007271_01 Info KIAA0894 protein H007271_01 AB020701 199117 KIAA0894 0.3201299 0.917
1618 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H003497_01 Info V-akt murine thymoma viral oncogene homolog 2 H003497_01 M77198 326445 AKT2 Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction, tsonc 0.3314111 0.872
1619 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H000650_01 Info Glycogen synthase kinase 3 beta H000650_01 L33801 78802 GSK3B ALK in cardiac myocytes, Cell Cycle: G1/S Check Point , Deregulation of CDK5 in Alzheimer’s Disease, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Multi-step Regulation of Transcription by Pitx2, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Presenilin action in Notch and Wnt signaling, Regulation of eIF2, Segmentation Clock, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Sonic Hedgehog (Shh) Pathway, WNT Signaling Pathway, Phosphatidylinositol signaling system 0.353328 1.118
1620 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H010532_01 Info Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide H010532_01 U54778 79474 YWHAE Lissencephaly gene (LIS1) in neuronal migration and development 0.3886293 1.083
1621 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H013009_01 Info Adenylyl cyclase-associated protein H013009_01 L12168 104125 CAP 0.4133824 1.094
1622 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H002745_01 Info Inositol polyphosphate phosphatase-like 1 H002745_01 Y14385 75339 INPPL1 Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Inositol phosphate metabolism, Phosphatidylinositol signaling system, DNA_damage 0.5531012 1.065
1623 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H008369_01 Info Tax interaction protein 40 H008369_01 NM_016948 112933 TAX40 0.5577165 1.057
1624 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H004961_01 Info Flotillin 1 H004961_01 AF089750 179986 FLOT1 0.5740947 1.05
1625 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H010826_01 Info Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide H010826_01 AB024334 25001 YWHAG 0.6175419 1.047
1626 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H002173_01 Info Cell division cycle 42 (GTP-binding protein, 25kD) H002173_01 AL121735 146409 CDC42 Agrin in Postsynaptic Differentiation, How does salmonella hijack a cell, p38 MAPK Signaling Pathway , Ras Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, cell_cycle, cell_signaling, signal_transduction 0.6486191 1.035
1627 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H003698_01 Info Protein tyrosine phosphatase, non-receptor type 1 H003698_01 M31724 155894 PTPN1 cell_cycle, cell_signaling 0.6633733 1.054
1628 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H003612_01 Info V-akt murine thymoma viral oncogene homolog 1 H003612_01 M63167 71816 AKT1 Actions of Nitric Oxide in the Heart, AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, B Cell Survival Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia and p53 in the Cardiovascular system, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, mTOR Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Phospholipase C Signaling Pathway, Phospholipids as signaling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Ras Signaling Pathway, Regulation … 0.6741257 1.038
1629 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H003654_01 Info Coagulation factor II (thrombin) receptor-like 2 H003654_01 U92971 194351 F2RL2 immunology 0.6746058 0.966
1630 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H011166_01 Info Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide H011166_01 X57346 279920 YWHAB 0.8206709 0.982
1631 crebPathway_h CREB is a transcription factor that binds to cAMP-responsive elements (CREs) to activate transcription in response to extracellular signaling. H002055_01 Info Growth factor receptor-bound protein 2 H002055_01 M96995 296381 GRB2 Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel … 0.0022348 1.459
1632 crebPathway_h CREB is a transcription factor that binds to cAMP-responsive elements (CREs) to activate transcription in response to extracellular signaling. H003415_01 Info Protein kinase, cAMP-dependent, catalytic, beta H003415_01 M34181 87773 PRKACB Perou’s – Intrinsic – Breast-Cancer-Genes, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.0048904 0.647
1633 crebPathway_h CREB is a transcription factor that binds to cAMP-responsive elements (CREs) to activate transcription in response to extracellular signaling. H002895_01 Info Mitogen-activated protein kinase 14 H002895_01 L35263 79107 MAPK14 BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAP Kinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm … 0.0086925 1.429
1634 crebPathway_h CREB is a transcription factor that binds to cAMP-responsive elements (CREs) to activate transcription in response to extracellular signaling. H002890_01 Info Ribosomal protein S6 kinase, 90kD, polypeptide 1 H002890_01 L07597 149957 RPS6KA1 Cell Cycle: G2/M Checkpoint, Erk1/Erk2 Mapk Signaling pathway, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, MAP Kinase Signaling Pathway, Melanocyte Development and Pigmentation Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of BAD phosphorylation, Role of Erk5 in Neuronal Survival, Transcription factor CREB and its extracellular signals, Phosphatidylinositol signaling system 0.0138896 1.42
1635 crebPathway_h CREB is a transcription factor that binds to cAMP-responsive elements (CREs) to activate transcription in response to extracellular signaling. H001365_01 Info Protein kinase C, beta 1 H001365_01 X07109 77202 PRKCB1 Bioactive Peptide Induced Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Ion Channel and Phorbol Esters Signaling Pathway, T Cell Receptor Signaling Pathway, Phosphatidylinositol signaling system, angiogenesis, cell_cycle, cell_signaling, signal_transduction 0.0304335 1.379
1636 crebPathway_h CREB is a transcription factor that binds to cAMP-responsive elements (CREs) to activate transcription in response to extracellular signaling. H005657_01 Info Calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma H005657_01 L07044 250857 CAMK2G Bioactive Peptide Induced Signaling Pathway, Ca++/ Calmodulin-dependent Protein Kinase Activation, Regulation of PGC-1a, Stathmin and breast cancer resistance to antimicrotubule agents, Transcription factor CREB and its extracellular signals 0.0367532 1.297
1637 crebPathway_h CREB is a transcription factor that binds to cAMP-responsive elements (CREs) to activate transcription in response to extracellular signaling. H003178_01 Info Mitogen-activated protein kinase 3 H003178_01 X60188 861 MAPK3 Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … 0.0986041 1.184
1638 crebPathway_h CREB is a transcription factor that binds to cAMP-responsive elements (CREs) to activate transcription in response to extracellular signaling. H012917_01 Info Homo sapiens clone 25048 mRNA sequence H012917_01 AF131776 321572 0.1524925 0.87
1639 crebPathway_h CREB is a transcription factor that binds to cAMP-responsive elements (CREs) to activate transcription in response to extracellular signaling. H002501_01 Info Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) H002501_01 D25274 173737 RAC1 Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, fMLP induced chemokine gene expression in HMC-1 cells, How does salmonella hijack a cell, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , Phosphoinositides and their downstream targets., Phospholipids as signaling intermediaries, Rac 1 cell motility signaling pathway, Ras Signaling Pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of MAL in Rho-Mediated Activation of SRF, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, T Cell Receptor Signaling Pathway, Transcription factor CREB and its extracellular signals, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, uCalpain and friends in Cell spread, Y branching of actin filaments 0.1980127 1.118
1640 crebPathway_h CREB is a transcription factor that binds to cAMP-responsive elements (CREs) to activate transcription in response to extracellular signaling. H001698_01 Info Protein kinase, cAMP-dependent, regulatory, type II, alpha H001698_01 X14968 289075 PRKAR2A AKAP95 role in mitosis and chromosome dynamics, Protein Kinase A at the Centrosome, Rho-Selective Guanine Exchange Factor AKAP13 Mediates Stress Fiber Formation 0.2569617 1.125
1641 crebPathway_h CREB is a transcription factor that binds to cAMP-responsive elements (CREs) to activate transcription in response to extracellular signaling. H000645_01 Info Protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) H000645_01 M33336 183037 PRKAR1A Activation of cAMP-dependent protein kinase, PKA, cell_cycle, cell_signaling, signal_transduction 0.4305614 0.935
1642 crebPathway_h CREB is a transcription factor that binds to cAMP-responsive elements (CREs) to activate transcription in response to extracellular signaling. H003612_01 Info V-akt murine thymoma viral oncogene homolog 1 H003612_01 M63167 71816 AKT1 Actions of Nitric Oxide in the Heart, AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, B Cell Survival Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia and p53 in the Cardiovascular system, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, mTOR Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Phospholipase C Signaling Pathway, Phospholipids as signaling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Ras Signaling Pathway, Regulation … 0.6741257 1.038
1643 crebPathway_h CREB is a transcription factor that binds to cAMP-responsive elements (CREs) to activate transcription in response to extracellular signaling. H006522_01 Info Neuroendocrine secretory protein 55 H006522_01 AF105253 113368 NESP55 Perou’s – Intrinsic – Breast-Cancer-Genes, Activation of cAMP-dependent protein kinase, PKA, Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, Attenuation of GPCR Signaling, CCR3 signaling in Eosinophils, ChREBP regulation by carbohydrates and cAMP, Corticosteroids and cardioprotection, Cystic fibrosis transmembrane conductance regulator (CFTR) and beta 2 adrenergic receptor (b2AR) pathway, Erk1/Erk2 Mapk Signaling pathway, How Progesterone Initiates the Oocyte Maturation, Ion Channels and Their Functional Role in Vascular Endothelium, Phospholipase C-epsilon pathway, Regulation of Spermatogenesis by CREM, Role of �-arrestins in the activation and targeting of MAP kinases, Roles of �-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling, Signaling Pathway from G-Protein Families, �-arrestins in GPCR Desensitization, Transcription factor CREB and its extracellular signals 0.7456375 1.036
1644 crebPathway_h CREB is a transcription factor that binds to cAMP-responsive elements (CREs) to activate transcription in response to extracellular signaling. H003163_01 Info CAMP responsive element binding protein 1 H003163_01 M27691 79194 CREB1 Ca++/ Calmodulin-dependent Protein Kinase Activation, Calcium Signaling by HBx of Hepatitis B virus, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia-Inducible Factor in the Cardiovascular System, Inhibition of Huntington\’s disease neurodegeneration by histone deacetylase inhibitors, MAP Kinase Signaling Pathway, Melanocyte Development and Pigmentation Pathway, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Repression of Pain Sensation by the Transcriptional Regulator DREAM, Role of Erk5 in Neuronal Survival, Signaling Pathway from G-Protein Families, Transcription factor CREB and its extracellular signals, Transcription Regulation by Methyltransferase of CARM1, immunology 0.9300928 1.009
1645 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H003352_01 Info Interleukin 1 receptor, type I H003352_01 M27492 82112 IL1R1 NF-kB Signaling Pathway, Signal transduction through IL1R, immunology 0.000502 0.677
1646 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H002486_01 Info Glucokinase (hexokinase 4, maturity onset diabetes of the young 2) H002486_01 M90299 1270 GCK Aminosugars metabolism, Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Starch and sucrose metabolism, Streptomycin biosynthesis, immunology 0.0014569 1.288
1647 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H004176_01 Info Mitogen-activated protein kinase kinase kinase 11 H004176_01 L32976 89449 MAP3K11 MAP Kinase Signaling Pathway 0.0101996 1.263
1648 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H003611_01 Info Mitogen-activated protein kinase kinase 4 H003611_01 L36870 75217 MAP2K4 Perou’s – Intrinsic – Breast-Cancer-Genes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Ceramide Signaling Pathway, EGF Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, Inhibition of Cellular Proliferation by Gleevec, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , PDGF Signaling Pathway, T Cell Receptor Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system 0.012502 0.753
1649 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H003008_01 Info Mitogen-activated protein kinase kinase kinase 4 H003008_01 AF002715 32353 MAP3K4 MAP Kinase Signaling Pathway, Phosphatidylinositol signaling system 0.0127738 0.707
1650 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H001992_01 Info Activating transcription factor 2 H001992_01 X15875 198166 ATF2 ALK in cardiac myocytes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , The 4-1BB-dependent immune response, The information-processing pathway at the IFN-beta enhancer 0.0178377 0.749
1651 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H002789_01 Info Tumor protein p53 (Li-Fraumeni syndrome) H002789_01 NM_000546 1846 TP53 Apoptotic Signaling in Response to DNA Damage, ATM Signaling Pathway, BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Chaperones modulate interferon Signaling Pathway, CTCF: First Multivalent Nuclear Factor, Double Stranded RNA Induced Gene Expression, Estrogen-responsive protein Efp controls cell cycle and breast tumors growth, Hypoxia and p53 in the Cardiovascular system, Overview of telomerase protein component gene hTert Transcriptional Regulation , p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of cell cycle progression by Plk3, Regulation of transcriptional activity by PML, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, DNA_damage, gene_regulation, immunology, transcription, tsonc 0.0273242 1.207
1652 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H002588_01 Info Mitogen-activated protein kinase 7 H002588_01 U29725 3080 MAPK7 Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), MAP Kinase Signaling Pathway, Role of Erk5 in Neuronal Survival, Phosphatidylinositol signaling system 0.0614441 0.811
1653 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H008870_01 Info Sterile-alpha motif and leucine zipper containing kinase AZK H008870_01 AF251441 115175 ZAK Phosphatidylinositol signaling system 0.1273337 1.204
1654 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H003158_01 Info Mitogen-activated protein kinase 8 H003158_01 L26318 190913 MAPK8 Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig … 0.1287835 1.166
1655 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H000029_01 Info Mitogen-activated protein kinase kinase kinase 3 H000029_01 U78876 29282 MAP3K3 MAP Kinase Signaling Pathway, Phosphatidylinositol signaling system 0.2027051 1.138
1656 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H002632_01 Info GRB2-associated binding protein 1 H002632_01 U43885 239706 GAB1 Signaling of Hepatocyte Growth Factor Receptor 0.3021702 1.095
1657 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H003309_01 Info Mitogen-activated protein kinase kinase 7 H003309_01 AF013589 110299 MAP2K7 Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Keratinocyte Differentiation, MAP Kinase Signaling Pathway 0.3044184 1.088
1658 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H002559_01 Info Mitogen-activated protein kinase kinase kinase 12 H002559_01 U07358 211601 MAP3K12 MAP Kinase Signaling Pathway, Phosphatidylinositol signaling system 0.3172697 1.101
1659 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H008351_01 Info Dual specificity phosphatase 10 H008351_01 AB026436 177534 DUSP10 0.382916 0.922
1660 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H006851_01 Info TAK1-binding protein 2; KIAA0733 protein H006851_01 AL117407 109727 KIAA0733 Toll-Like Receptor Pathway 0.4908732 1.066
1661 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H002340_01 Info Mitogen-activated protein kinase kinase kinase 5 H002340_01 U67156 151988 MAP3K5 HIV-I Nef: negative effector of Fas and TNF, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , The 4-1BB-dependent immune response 0.5393151 1.07
1662 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H002173_01 Info Cell division cycle 42 (GTP-binding protein, 25kD) H002173_01 AL121735 146409 CDC42 Agrin in Postsynaptic Differentiation, How does salmonella hijack a cell, p38 MAPK Signaling Pathway , Ras Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, cell_cycle, cell_signaling, signal_transduction 0.6486191 1.035
1663 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H003612_01 Info V-akt murine thymoma viral oncogene homolog 1 H003612_01 M63167 71816 AKT1 Actions of Nitric Oxide in the Heart, AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, B Cell Survival Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia and p53 in the Cardiovascular system, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, mTOR Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Phospholipase C Signaling Pathway, Phospholipids as signaling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Ras Signaling Pathway, Regulation … 0.6741257 1.038
1664 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H001386_01 Info Mitogen-activated protein kinase kinase kinase 10 H001386_01 X90846 30223 MAP3K10 MAP Kinase Signaling Pathway, Phosphatidylinositol signaling system 0.7007387 0.968
1665 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H002470_01 Info Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 H002470_01 L41067 172674 NFATC3 immunology 0.7190859 0.97
1666 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H000479_01 Info Dual specificity phosphatase 8 H000479_01 U27193 41688 DUSP8 Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases 0.7214843 1.03
1667 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H001715_01 Info Dual specificity phosphatase 4 H001715_01 AL137704 2359 DUSP4 Perou’s – Intrinsic – Breast-Cancer-Genes, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, cell_cycle, cell_signaling 0.9634643 1.004
1668 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H014820_01 Info Mitogen-activated protein kinase 9 H014820_01 NM_002752 246857 MAPK9 MAP Kinase Signaling Pathway, Phosphatidylinositol signaling system 0.9883614 0.998
1669 radiation_sensitivity_h BioCarta H001935_01 Info Glyceraldehyde-3-phosphate dehydrogenase H001935_01 U34995 169476 GAPD 0.0001082 1.485
1670 radiation_sensitivity_h BioCarta H002040_01 Info Epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog) H002040_01 X00588 77432 EGFR Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Keratinocyte Differentiation, Map Kinase Inactivation of SMRT Corepressor, mCalpain and friends in Cell motility, Neuroregulin receptor degradation protein-1 Controls ErbB3 receptor recycling, Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Role of ERBB2 in Signal Transduction and Oncology, Sprouty regulation of tyrosine kinase signals, Telomeres, Telomerase, Cellular Aging, and Immortality, The role of FYVE-finger proteins in vesicle transport, Trefoil Factors Initiate Mucosal Healing, angiogenesis, signal_transduction, tsonc 0.0004362 0.669
1671 radiation_sensitivity_h BioCarta H003112_01 Info Retinoblastoma 1 (including osteosarcoma) H003112_01 L41870 75770 RB1 BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Chaperones modulate interferon Signaling Pathway, Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase RNA component gene hTerc Transcriptional Regulation, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Regulation of transcriptional activity by PML, Telomeres, Telomerase, Cellular Aging, and Immortality, TNFR1 Signaling Pathway, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, immunology, tsonc 0.0008596 0.674
1672 radiation_sensitivity_h BioCarta H002681_01 Info Cyclin D3 H002681_01 M92287 83173 CCND3 Cyclins and Cell Cycle Regulation, cell_cycle 0.0084801 1.28
1673 radiation_sensitivity_h BioCarta H002092_01 Info Ataxia telangiectasia and Rad3 related H002092_01 U49844 77613 ATR Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Regulation of cell cycle progression by Plk3, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, Phosphatidylinositol signaling system, DNA_replication, immunology 0.0105491 0.753
1674 radiation_sensitivity_h BioCarta H003739_01 Info Cell division cycle 2, G1 to S and G2 to M H003739_01 X05360 184572 CDC2 Activation of Src by Protein-tyrosine phosphatase alpha, AKAP95 role in mitosis and chromosome dynamics, cdc25 and chk1 Regulatory Pathway in response to DNA damage, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, How Progesterone Initiates the Oocyte Maturation, Protein Kinase A at the Centrosome, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of Splicing through Sam68, Sonic Hedgehog (SHH) Receptor Ptc1 Regulates cell cycle, Stathmin and breast cancer resistance to antimicrotubule agents, Phosphatidylinositol signaling system, cell_cycle 0.0222229 0.733
1675 radiation_sensitivity_h BioCarta H002789_01 Info Tumor protein p53 (Li-Fraumeni syndrome) H002789_01 NM_000546 1846 TP53 Apoptotic Signaling in Response to DNA Damage, ATM Signaling Pathway, BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Chaperones modulate interferon Signaling Pathway, CTCF: First Multivalent Nuclear Factor, Double Stranded RNA Induced Gene Expression, Estrogen-responsive protein Efp controls cell cycle and breast tumors growth, Hypoxia and p53 in the Cardiovascular system, Overview of telomerase protein component gene hTert Transcriptional Regulation , p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of cell cycle progression by Plk3, Regulation of transcriptional activity by PML, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, DNA_damage, gene_regulation, immunology, transcription, tsonc 0.0273242 1.207
1676 radiation_sensitivity_h BioCarta H002149_01 Info Cyclin-dependent kinase inhibitor 1A (p21, Cip1) H002149_01 U03106 179665 CDKN1A ATM Signaling Pathway, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, Effects of calcineurin in Keratinocyte Differentiation, Erythropoietin mediated neuroprotection through NF-kB, Hypoxia and p53 in the Cardiovascular system, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, immunology, tsonc 0.0349766 1.236
1677 radiation_sensitivity_h BioCarta H002473_01 Info Insulin-like growth factor 1 receptor H002473_01 NM_000875 239176 IGF1R Perou’s – Intrinsic – Breast-Cancer-Genes, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Erk1/Erk2 Mapk Signaling pathway, IGF-1 Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of BAD phosphorylation, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Telomeres, Telomerase, Cellular Aging, and Immortality, The IGF-1 Receptor and Longevity, immunology 0.079692 1.158
1678 radiation_sensitivity_h BioCarta H002987_01 Info Cyclin B2 H002987_01 AK001404 194698 CCNB2 Estrogen-responsive protein Efp controls cell cycle and breast tumors growth 0.0829851 0.84
1679 radiation_sensitivity_h BioCarta H002323_01 Info Cyclin E1 H002323_01 M74093 9700 CCNE1 Perou’s – Intrinsic – Breast-Cancer-Genes, CDK Regulation of DNA Replication, Cell Cycle: G1/S Check Point , Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, Regulation of p27 Phosphorylation during Cell Cycle Progression, cell_cycle 0.1107382 0.884
1680 radiation_sensitivity_h BioCarta H002760_01 Info RAD51 (S. cerevisiae) homolog (E coli RecA homolog) H002760_01 D14134 23044 RAD51 ATM Signaling Pathway, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, DNA_damage, DNA_replication 0.1212274 1.154
1681 radiation_sensitivity_h BioCarta H003605_01 Info BCL2-associated X protein H003605_01 L22474 159428 BAX Apoptotic Signaling in Response to DNA Damage, Ceramide Signaling Pathway, Hypoxia and p53 in the Cardiovascular system, p53 Signaling Pathway, Regulation of BAD phosphorylation, Role of Mitochondria in Apoptotic Signaling, apoptosis, development, immunology 0.253339 0.907
1682 radiation_sensitivity_h BioCarta H003644_01 Info Tumor necrosis factor receptor superfamily, member 6 H003644_01 X63717 82359 TNFRSF6 apoptosis, immunology 0.4621499 0.927
1683 radiation_sensitivity_h BioCarta H003538_01 Info Actin, beta H003538_01 NM_001101 288061 ACTB Chromatin Remodeling by hSWI/SNF ATP-dependent Complexes 0.6253266 0.956
1684 radiation_sensitivity_h BioCarta H003542_01 Info V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (neuro/glioblastoma derived oncogene H003542_01 M11730 323910 ERBB2 Perou’s – Intrinsic – Breast-Cancer-Genes, Role of ERBB2 in Signal Transduction and Oncology, Trefoil Factors Initiate Mucosal Healing, immunology, signal_transduction, tsonc 0.7160857 1.031
1685 radiation_sensitivity_h BioCarta H006841_01 Info Homo sapiens mRNA; cDNA DKFZp564P073 (from clone DKFZp564P073) H006841_01 AL049301 278577 Apoptotic Signaling in Response to DNA Damage, Ceramide Signaling Pathway, Hypoxia and p53 in the Cardiovascular system, p53 Signaling Pathway, Regulation of BAD phosphorylation, Role of Mitochondria in Apoptotic Signaling, apoptosis, development, immunology 0.7810094 0.98
1686 radiation_sensitivity_h BioCarta H003766_01 Info Mouse double minute 2, human homolog of; p53-binding protein H003766_01 M92424 170027 MDM2 ATM Signaling Pathway, Cell Cycle: G2/M Checkpoint, CTCF: First Multivalent Nuclear Factor, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, p53 Signaling Pathway, Sumoylation by RanBP2 Regulates Transcriptional Repression, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, gene_regulation, transcription, tsonc 0.8018001 0.978
1687 radiation_sensitivity_h BioCarta H003816_01 Info Caspase 1, apoptosis-related cysteine protease (interleukin 1, beta, convertase) H003816_01 M87507 2490 CASP1 Caspase Cascade in Apoptosis, D4-GDI Signaling Pathway, IL 18 Signaling Pathway, apoptosis, immunology 0.9157209 1.011
1688 radiation_sensitivity_h BioCarta H003027_01 Info Cyclin D2 H003027_01 D13639 75586 CCND2 Cyclins and Cell Cycle Regulation, cell_cycle 0.9682473 0.996
1689 mtorPathway_h BioCarta H003305_01 Info Ribosomal protein S6 kinase, 70kD, polypeptide 1 H003305_01 M60724 86858 RPS6KB1 CTCF: First Multivalent Nuclear Factor, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, MAP Kinase Signaling Pathway, mTOR Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Rac 1 cell motility signaling pathway, Regulation of eIF4e and p70 S6 Kinase, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.0214523 1.448
1690 mtorPathway_h BioCarta H002633_01 Info FK506 binding protein 12-rapamycin associated protein 1 H002633_01 U88966 250723 FRAP1 B Cell Survival Pathway, CTCF: First Multivalent Nuclear Factor, mTOR Signaling Pathway, Regulation of eIF4e and p70 S6 Kinase, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Stat3 Signaling Pathway, immunology 0.0222345 1.277
1691 mtorPathway_h BioCarta H002145_01 Info FK506-binding protein 1A (12kD) H002145_01 M34539 752 FKBP1A mTOR Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart) 0.0298997 1.239
1692 mtorPathway_h BioCarta H005703_01 Info Eukaryotic translation initiation factor 4 gamma, 3 H005703_01 AF012072 25732 EIF4G3 Perou’s – Intrinsic – Breast-Cancer-Genes 0.0342104 1.272
1693 mtorPathway_h BioCarta H012604_01 Info Human clone 23933 mRNA sequence H012604_01 U79273 239483 Internal Ribosome entry pathway, mTOR Signaling Pathway, Regulation of eIF4e and p70 S6 Kinase 0.0546956 1.194
1694 mtorPathway_h BioCarta H013804_01 Info Eukaryotic translation initiation factor 4A, isoform 1 H013804_01 D13748 129673 EIF4A1 Internal Ribosome entry pathway, mTOR Signaling Pathway, Regulation of eIF4e and p70 S6 Kinase 0.1156946 1.148
1695 mtorPathway_h BioCarta H007640_01 Info Eukaryotic translation initiation factor 4A, isoform 2 H007640_01 AL117412 173912 EIF4A2 0.1166617 0.881
1696 mtorPathway_h BioCarta H003286_01 Info 3-phosphoinositide dependent protein kinase-1 H003286_01 AF017995 154729 PDPK1 Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.2543058 1.119
1697 mtorPathway_h BioCarta H003743_01 Info Eukaryotic translation initiation factor 4 gamma, 2 H003743_01 U73824 183684 EIF4G2 gene_regulation, immunology 0.4776424 0.941
1698 mtorPathway_h BioCarta H007698_01 Info Eukaryotic translation initiation factor 4E binding protein 1 H007698_01 L36055 71819 EIF4EBP1 mTOR Signaling Pathway, Regulation of eIF4e and p70 S6 Kinase, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway 0.5191259 1.06
1699 mtorPathway_h BioCarta H013300_01 Info Pyruvate dehydrogenase kinase, isoenzyme 2 H013300_01 L42451 92261 PDK2 mTOR Signaling Pathway, PTEN dependent cell cycle arrest and apoptosis, Regulation of eIF4e and p70 S6 Kinase, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, cell_cycle, cell_signaling, signal_transduction 0.5991595 0.949
1700 mtorPathway_h BioCarta H003612_01 Info V-akt murine thymoma viral oncogene homolog 1 H003612_01 M63167 71816 AKT1 Actions of Nitric Oxide in the Heart, AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, B Cell Survival Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia and p53 in the Cardiovascular system, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, mTOR Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Phospholipase C Signaling Pathway, Phospholipids as signaling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Ras Signaling Pathway, Regulation … 0.6741257 1.038
1701 mtorPathway_h BioCarta H010093_01 Info Eukaryotic translation initiation factor 3, subunit 10 (theta, 150/170kD) H010093_01 D50929 198899 EIF3S10 0.8934066 1.012
1702 mtorPathway_h BioCarta H012856_01 Info MAP kinase-interacting serine/threonine kinase 1 H012856_01 AB000409 5591 MKNK1 Erk1/Erk2 Mapk Signaling pathway, MAP Kinase Signaling Pathway, mTOR Signaling Pathway, p38 MAPK Signaling Pathway , Regulation of eIF4e and p70 S6 Kinase, Phosphatidylinositol signaling system 0.9455231 0.992
1703 glycolysisPathway_h BioCarta H001935_01 Info Glyceraldehyde-3-phosphate dehydrogenase H001935_01 U34995 169476 GAPD 0.0001082 1.485
1704 glycolysisPathway_h BioCarta H001878_01 Info Enolase 1, (alpha) H001878_01 M14328 254105 ENO1 Glycolysis Pathway, Glycolysis / Gluconeogenesis, Phenylalanine, tyrosine and tryptophan biosynthesis 0.0756084 1.187
1705 glycolysisPathway_h BioCarta H007138_01 Info Phosphoglycerate kinase {alternatively spliced} [human, phosphoglycerate kinase deficient patient wi H007138_01 S81916 169313 Glycolysis Pathway, Carbon fixation, Glycolysis / Gluconeogenesis, immunology 0.0923463 1.164
1706 glycolysisPathway_h BioCarta H001636_01 Info Phosphoglycerate mutase 1 (brain) H001636_01 J04173 181013 PGAM1 Glycolysis Pathway, Glycolysis / Gluconeogenesis, misc 0.2631445 1.109
1707 glycolysisPathway_h BioCarta H001385_01 Info Phosphofructokinase, liver H001385_01 X15573 155455 PFKL Glycolysis Pathway, Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Pentose phosphate pathway, immunology 0.9581627 1.005
1708 shh_lisa_h Manually Curated H002412_01 Info Cyclin-dependent kinase 2 H002412_01 M68520 19192 CDK2 CDK Regulation of DNA Replication, Cell Cycle: G1/S Check Point , Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, immunology, signal_transduction 0.0040171 0.711
1709 shh_lisa_h Manually Curated H003415_01 Info Protein kinase, cAMP-dependent, catalytic, beta H003415_01 M34181 87773 PRKACB Perou’s – Intrinsic – Breast-Cancer-Genes, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.0048904 0.647
1710 shh_lisa_h Manually Curated H003183_01 Info Cyclin-dependent kinase 8 H003183_01 X85753 25283 CDK8 Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.0083884 0.714
1711 shh_lisa_h Manually Curated H000211_01 Info Glioma-associated oncogene homolog (zinc finger protein) H000211_01 X07384 2693 GLI development, gene_regulation, transcription, tsonc 0.0229022 0.821
1712 shh_lisa_h Manually Curated H002371_01 Info Cyclin B1 H002371_01 M25753 23960 CCNB1 Activation of Src by Protein-tyrosine phosphatase alpha, AKAP95 role in mitosis and chromosome dynamics, Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, How Progesterone Initiates the Oocyte Maturation, Sonic Hedgehog (SHH) Receptor Ptc1 Regulates cell cycle, Stathmin and breast cancer resistance to antimicrotubule agents, cell_cycle 0.037756 0.797
1713 shh_lisa_h Manually Curated H001698_01 Info Protein kinase, cAMP-dependent, regulatory, type II, alpha H001698_01 X14968 289075 PRKAR2A AKAP95 role in mitosis and chromosome dynamics, Protein Kinase A at the Centrosome, Rho-Selective Guanine Exchange Factor AKAP13 Mediates Stress Fiber Formation 0.2569617 1.125
1714 shh_lisa_h Manually Curated H000650_01 Info Glycogen synthase kinase 3 beta H000650_01 L33801 78802 GSK3B ALK in cardiac myocytes, Cell Cycle: G1/S Check Point , Deregulation of CDK5 in Alzheimer’s Disease, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Multi-step Regulation of Transcription by Pitx2, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Presenilin action in Notch and Wnt signaling, Regulation of eIF2, Segmentation Clock, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Sonic Hedgehog (Shh) Pathway, WNT Signaling Pathway, Phosphatidylinositol signaling system 0.353328 1.118
1715 shh_lisa_h Manually Curated H002127_01 Info Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A H002127_01 D86550 75842 DYRK1A Sonic Hedgehog (Shh) Pathway 0.4628734 0.926
1716 shh_lisa_h Manually Curated H002675_01 Info Patched (Drosophila) homolog H002675_01 U43148 159526 PTCH Sonic Hedgehog (Shh) Pathway, Sonic Hedgehog (SHH) Receptor Ptc1 Regulates cell cycle, angiogenesis, development, immunology, metastasis, tsonc 0.4755683 0.942
1717 shh_lisa_h Manually Curated H000557_01 Info Exportin 1 (CRM1, yeast, homolog) H000557_01 Y08614 79090 XPO1 Regulation of Spermatogenesis by CREM, Sonic Hedgehog (SHH) Receptor Ptc1 Regulates cell cycle, gene_regulation, transcription 0.5346168 0.946
1718 shh_lisa_h Manually Curated H002165_01 Info Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 H002165_01 Y13493 173135 DYRK2 Phosphatidylinositol signaling system, signal_transduction 0.6071417 1.067
1719 shh_lisa_h Manually Curated H006274_01 Info Ras protein-specific guanine nucleotide-releasing factor 1 H006274_01 L26584 169350 RASGRF1 Activation of Src by Protein-tyrosine phosphatase alpha, cdc25 and chk1 Regulatory Pathway in response to DNA damage, Cell Cycle: G2/M Checkpoint, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Sonic Hedgehog (SHH) Receptor Ptc1 Regulates cell cycle 0.7256743 1.03
1720 shh_lisa_h Manually Curated H000610_01 Info Glioma pathogenesis-related protein H000610_01 U16307 64639 RTVP1 0.9468739 1.009
1721 ST_G_alpha_5_Pathway_h Signalling Transduction KE H002893_01 Info V-raf-1 murine leukemia viral oncogene homolog 1 H002893_01 X03484 85181 RAF1 Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … 0.0062484 1.596
1722 ST_G_alpha_5_Pathway_h Signalling Transduction KE H000309_01 Info CAMP response element-binding protein CRE-BPa H000309_01 L05515 149 H_GS165L15.1 0.0078273 1.479
1723 ST_G_alpha_5_Pathway_h Signalling Transduction KE H001062_01 Info N-acylsphingosine amidohydrolase (acid ceramidase) H001062_01 U70063 75811 ASAH Perou’s – Intrinsic – Breast-Cancer-Genes, Activation of cAMP-dependent protein kinase, PKA, Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, ChREBP regulation by carbohydrates and cAMP, Cystic fibrosis transmembrane conductance regulator (CFTR) and beta 2 adrenergic receptor (b2AR) pathway, How Progesterone Initiates the Oocyte Maturation, Ion Channels and Their Functional Role in Vascular Endothelium, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Phospholipase C-epsilon pathway, Phospholipids as signaling intermediaries, Regulation of BAD phosphorylation, Regulation of Spermatogenesis by CREM, Role of �-arrestins in the activation and targeting of MAP kinases, Roles of �-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling, Signaling Pathway from G-Protein Families, �-arrestins in GPCR Desensitization, Thrombin signaling and protease-activated receptors, Transcription factor CREB and its … 0.0187984 1.357
1724 ST_G_alpha_5_Pathway_h Signalling Transduction KE H002943_01 Info V-raf murine sarcoma viral oncogene homolog B1 H002943_01 M95712 622 BRAF MAP Kinase Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction, tsonc 0.2376595 0.895
1725 ST_G_alpha_5_Pathway_h Signalling Transduction KE H003337_01 Info B-factor, properdin H003337_01 L15702 69771 BF Perou’s – Intrinsic – Breast-Cancer-Genes, immunology 0.3702495 1.093
1726 ST_G_alpha_5_Pathway_h Signalling Transduction KE H007842_01 Info Gastrin H007842_01 NM_000805 2681 GAS immunology 0.6295543 1.041
1727 ST_G_alpha_5_Pathway_h Signalling Transduction KE H003163_01 Info CAMP responsive element binding protein 1 H003163_01 M27691 79194 CREB1 Ca++/ Calmodulin-dependent Protein Kinase Activation, Calcium Signaling by HBx of Hepatitis B virus, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia-Inducible Factor in the Cardiovascular System, Inhibition of Huntington\’s disease neurodegeneration by histone deacetylase inhibitors, MAP Kinase Signaling Pathway, Melanocyte Development and Pigmentation Pathway, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Repression of Pain Sensation by the Transcriptional Regulator DREAM, Role of Erk5 in Neuronal Survival, Signaling Pathway from G-Protein Families, Transcription factor CREB and its extracellular signals, Transcription Regulation by Methyltransferase of CARM1, immunology 0.9300928 1.009
1728 ptdinsPathway_h BioCarta H003000_01 Info RAB5A, member RAS oncogene family H003000_01 M28215 73957 RAB5A Phosphoinositides and their downstream targets., Rab GTPases Mark Targets In The Endocytotic Machinery, The role of FYVE-finger proteins in vesicle transport, tsonc 0.0003278 0.591
1729 ptdinsPathway_h BioCarta H002878_01 Info V-yes-1 Yamaguchi sarcoma viral related oncogene homolog H002878_01 M16038 80887 LYN BCR Signaling Pathway, Eph Kinases and ephrins support platelet aggregation, Fc Epsilon Receptor I Signaling in Mast Cells, Phosphoinositides and their downstream targets., immunology, signal_transduction, tsonc 0.0068841 1.545
1730 ptdinsPathway_h BioCarta H003305_01 Info Ribosomal protein S6 kinase, 70kD, polypeptide 1 H003305_01 M60724 86858 RPS6KB1 CTCF: First Multivalent Nuclear Factor, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, MAP Kinase Signaling Pathway, mTOR Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Rac 1 cell motility signaling pathway, Regulation of eIF4e and p70 S6 Kinase, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.0214523 1.448
1731 ptdinsPathway_h BioCarta H001739_01 Info Adaptor-related protein complex 2, mu 1 subunit H001739_01 D63475 152936 AP2M1 0.0326931 0.787
1732 ptdinsPathway_h BioCarta H001590_01 Info Early endosome antigen 1, 162kD H001590_01 L40157 2864 EEA1 Phosphoinositides and their downstream targets., The role of FYVE-finger proteins in vesicle transport 0.0683087 0.8
1733 ptdinsPathway_h BioCarta H001387_01 Info Phosphofructokinase, platelet H001387_01 D25328 99910 PFKP Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Pentose phosphate pathway, immunology 0.101431 0.866
1734 ptdinsPathway_h BioCarta H002501_01 Info Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) H002501_01 D25274 173737 RAC1 Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, fMLP induced chemokine gene expression in HMC-1 cells, How does salmonella hijack a cell, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , Phosphoinositides and their downstream targets., Phospholipids as signaling intermediaries, Rac 1 cell motility signaling pathway, Ras Signaling Pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of MAL in Rho-Mediated Activation of SRF, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, T Cell Receptor Signaling Pathway, Transcription factor CREB and its extracellular signals, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, uCalpain and friends in Cell spread, Y branching of actin filaments 0.1980127 1.118
1735 ptdinsPathway_h BioCarta H002457_01 Info Protein kinase C, zeta H002457_01 Z15108 78793 PRKCZ Phosphoinositides and their downstream targets., Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.2375152 0.898
1736 ptdinsPathway_h BioCarta H003870_01 Info Bruton agammaglobulinemia tyrosine kinase H003870_01 NM_000061 159494 BTK BCR Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Phosphoinositides and their downstream targets., cell_cycle, cell_signaling, immunology, signal_transduction 0.251649 1.148
1737 ptdinsPathway_h BioCarta H003286_01 Info 3-phosphoinositide dependent protein kinase-1 H003286_01 AF017995 154729 PDPK1 Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.2543058 1.119
1738 ptdinsPathway_h BioCarta H001378_01 Info Phosphofructokinase, muscle H001378_01 U24183 75160 PFKM Phosphoinositides and their downstream targets., Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Pentose phosphate pathway, immunology 0.2927445 0.908
1739 ptdinsPathway_h BioCarta H001586_01 Info ADP-ribosylation factor 1 H001586_01 AK000620 74571 ARF1 ADP-Ribosylation Factor, Phosphoinositides and their downstream targets. 0.3260826 1.087
1740 ptdinsPathway_h BioCarta H000650_01 Info Glycogen synthase kinase 3 beta H000650_01 L33801 78802 GSK3B ALK in cardiac myocytes, Cell Cycle: G1/S Check Point , Deregulation of CDK5 in Alzheimer’s Disease, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Multi-step Regulation of Transcription by Pitx2, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Presenilin action in Notch and Wnt signaling, Regulation of eIF2, Segmentation Clock, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Sonic Hedgehog (Shh) Pathway, WNT Signaling Pathway, Phosphatidylinositol signaling system 0.353328 1.118
1741 ptdinsPathway_h BioCarta H003612_01 Info V-akt murine thymoma viral oncogene homolog 1 H003612_01 M63167 71816 AKT1 Actions of Nitric Oxide in the Heart, AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, B Cell Survival Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia and p53 in the Cardiovascular system, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, mTOR Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Phospholipase C Signaling Pathway, Phospholipids as signaling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Ras Signaling Pathway, Regulation … 0.6741257 1.038
1742 ptdinsPathway_h BioCarta H001974_01 Info BCL2-antagonist of cell death H001974_01 U66879 76366 BAD AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, Ceramide Signaling Pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Phosphoinositides and their downstream targets., Ras Signaling Pathway, Regulation of BAD phosphorylation, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Trefoil Factors Initiate Mucosal Healing, apoptosis, development 0.6985187 0.954
1743 ptdinsPathway_h BioCarta H001385_01 Info Phosphofructokinase, liver H001385_01 X15573 155455 PFKL Glycolysis Pathway, Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Pentose phosphate pathway, immunology 0.9581627 1.005
1744 insulin_signaling_h BioCarta H001935_01 Info Glyceraldehyde-3-phosphate dehydrogenase H001935_01 U34995 169476 GAPD 0.0001082 1.485
1745 insulin_signaling_h BioCarta H000732_01 Info Insulin receptor substrate 1 H000732_01 S62539 96063 IRS1 Perou’s – Intrinsic – Breast-Cancer-Genes, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Insulin Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of eIF4e and p70 S6 Kinase, immunology 0.0013348 0.643
1746 insulin_signaling_h BioCarta H002486_01 Info Glucokinase (hexokinase 4, maturity onset diabetes of the young 2) H002486_01 M90299 1270 GCK Aminosugars metabolism, Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Starch and sucrose metabolism, Streptomycin biosynthesis, immunology 0.0014569 1.288
1747 insulin_signaling_h BioCarta H002055_01 Info Growth factor receptor-bound protein 2 H002055_01 M96995 296381 GRB2 Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel … 0.0022348 1.459
1748 insulin_signaling_h BioCarta H002893_01 Info V-raf-1 murine leukemia viral oncogene homolog 1 H002893_01 X03484 85181 RAF1 Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … 0.0062484 1.596
1749 insulin_signaling_h BioCarta H002890_01 Info Ribosomal protein S6 kinase, 90kD, polypeptide 1 H002890_01 L07597 149957 RPS6KA1 Cell Cycle: G2/M Checkpoint, Erk1/Erk2 Mapk Signaling pathway, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, MAP Kinase Signaling Pathway, Melanocyte Development and Pigmentation Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of BAD phosphorylation, Role of Erk5 in Neuronal Survival, Transcription factor CREB and its extracellular signals, Phosphatidylinositol signaling system 0.0138896 1.42
1750 insulin_signaling_h BioCarta H003305_01 Info Ribosomal protein S6 kinase, 70kD, polypeptide 1 H003305_01 M60724 86858 RPS6KB1 CTCF: First Multivalent Nuclear Factor, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, MAP Kinase Signaling Pathway, mTOR Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Rac 1 cell motility signaling pathway, Regulation of eIF4e and p70 S6 Kinase, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.0214523 1.448
1751 insulin_signaling_h BioCarta H002633_01 Info FK506 binding protein 12-rapamycin associated protein 1 H002633_01 U88966 250723 FRAP1 B Cell Survival Pathway, CTCF: First Multivalent Nuclear Factor, mTOR Signaling Pathway, Regulation of eIF4e and p70 S6 Kinase, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Stat3 Signaling Pathway, immunology 0.0222345 1.277
1752 insulin_signaling_h BioCarta H006288_01 Info AE-binding protein 1 H006288_01 AF053944 118397 AEBP1 0.0298793 0.787
1753 insulin_signaling_h BioCarta H001365_01 Info Protein kinase C, beta 1 H001365_01 X07109 77202 PRKCB1 Bioactive Peptide Induced Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Ion Channel and Phorbol Esters Signaling Pathway, T Cell Receptor Signaling Pathway, Phosphatidylinositol signaling system, angiogenesis, cell_cycle, cell_signaling, signal_transduction 0.0304335 1.379
1754 insulin_signaling_h BioCarta H002997_01 Info Vascular endothelial growth factor H002997_01 AF022375 73793 VEGF Actions of Nitric Oxide in the Heart, Hypoxia-Inducible Factor in the Cardiovascular System, VEGF, Hypoxia, and Angiogenesis, angiogenesis, misc 0.0306231 0.782
1755 insulin_signaling_h BioCarta H016134_01 Info V-akt murine thymoma viral oncogene homolog 2 H016134_01 NM_001626 326445 AKT2 Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction, tsonc 0.0530988 1.287
1756 insulin_signaling_h BioCarta H014573_01 Info Homo sapiens HSPC106 mRNA, partial CDS H014573_01 AF161369 187763 How Progesterone Initiates the Oocyte Maturation 0.0559133 0.793
1757 insulin_signaling_h BioCarta H007864_01 Info Solute carrier family 27 (fatty acid transporter), member 4 H007864_01 AF055899 248953 SLC27A4 0.07271 0.822
1758 insulin_signaling_h BioCarta H001676_01 Info Protein kinase C, iota H001676_01 L33881 1904 PRKCI Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.0761126 0.777
1759 insulin_signaling_h BioCarta H010696_01 Info NCK adaptor protein 2 H010696_01 AF047487 101695 NCK2 0.1245534 1.19
1760 insulin_signaling_h BioCarta H014546_01 Info Peptidylprolyl isomerase A (cyclophilin A) H014546_01 NM_021130 182937 PPIA IL-2 Receptor Beta Chain in T cell Activation 0.129858 1.176
1761 insulin_signaling_h BioCarta H006546_01 Info Neuronal Shc H006546_01 D84361 151123 SHC3 0.1304854 1.158
1762 insulin_signaling_h BioCarta H001682_01 Info Oncogene TC21 H001682_01 M31468 206097 TC21 0.1382996 1.119
1763 insulin_signaling_h BioCarta H002248_01 Info Glucose-6-phosphate dehydrogenase H002248_01 X03674 80206 G6PD Glutathione metabolism, Pentose phosphate pathway, immunology 0.1773825 0.891
1764 insulin_signaling_h BioCarta H005943_01 Info Docking protein 1, 62kD (downstream of tyrosine kinase 1) H005943_01 AF035299 103854 DOK1 0.179807 1.125
1765 insulin_signaling_h BioCarta H003783_01 Info Sterol regulatory element binding transcription factor 1 H003783_01 U00968 166 SREBF1 SREBP control of lipid synthesis 0.2210756 0.895
1766 insulin_signaling_h BioCarta H002750_01 Info Neuropeptide Y H002750_01 K01911 1832 NPY 0.2221305 1.126
1767 insulin_signaling_h BioCarta H000420_01 Info Eukaryotic translation initiation factor 2B, subunit 1 (alpha, 26kD) H000420_01 X95648 78592 EIF2B1 gene_regulation 0.2277796 0.855
1768 insulin_signaling_h BioCarta H003042_01 Info BCL2-like 1 H003042_01 Z23115 305890 BCL2L1 Apoptotic Signaling in Response to DNA Damage, IL-2 Receptor Beta Chain in T cell Activation, Opposing roles of AIF in Apoptosis and Cell Survival, Ras Signaling Pathway, Regulation of BAD phosphorylation, Role of Mitochondria in Apoptotic Signaling, apoptosis, immunology 0.2336065 1.143
1769 insulin_signaling_h BioCarta H002457_01 Info Protein kinase C, zeta H002457_01 Z15108 78793 PRKCZ Phosphoinositides and their downstream targets., Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.2375152 0.898
1770 insulin_signaling_h BioCarta H002943_01 Info V-raf murine sarcoma viral oncogene homolog B1 H002943_01 M95712 622 BRAF MAP Kinase Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction, tsonc 0.2376595 0.895
1771 insulin_signaling_h BioCarta H003286_01 Info 3-phosphoinositide dependent protein kinase-1 H003286_01 AF017995 154729 PDPK1 Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.2543058 1.119
1772 insulin_signaling_h BioCarta H002947_01 Info Protein phosphatase 1, catalytic subunit, alpha isoform H002947_01 S57501 183994 PPP1CA cell_cycle, cell_signaling 0.2817559 1.112
1773 insulin_signaling_h BioCarta H006615_01 Info Acetyl-Coenzyme A carboxylase beta H006615_01 U89344 183857 ACACB Fatty acid biosynthesis (path 1), Propanoate metabolism, Pyruvate metabolism 0.2905076 1.107
1774 insulin_signaling_h BioCarta H002652_01 Info Uncoupling protein 2 (mitochondrial, proton carrier) H002652_01 U94592 80658 UCP2 immunology, misc 0.2962436 1.12
1775 insulin_signaling_h BioCarta H002632_01 Info GRB2-associated binding protein 1 H002632_01 U43885 239706 GAB1 Signaling of Hepatocyte Growth Factor Receptor 0.3021702 1.095
1776 insulin_signaling_h BioCarta H002405_01 Info Mitogen-activated protein kinase kinase 2 H002405_01 L11285 72241 MAP2K2 Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Bioactive Peptide Induced Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, fMLP induced chemokine gene expression in HMC-1 cells, Human Cytomegalovirus and Map Kinase Pathways, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Phosphorylation of MEK1 by cdk5/p35 down regulates the MAP kinase pathway, Role of MAL in Rho-Mediated Activation of SRF, Role of �-arrestins in the activation and targeting of MAP kinases, Roles of �-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling, Signaling of Hepatocyte Growth Factor Receptor 0.3118803 1.093
1777 insulin_signaling_h BioCarta H007271_01 Info KIAA0894 protein H007271_01 AB020701 199117 KIAA0894 0.3201299 0.917
1778 insulin_signaling_h BioCarta H001136_01 Info Glucose-6-phosphatase, catalytic (glycogen storage disease type I, von Gierke disease) H001136_01 U01120 242 G6PC Galactose metabolism, Glycolysis / Gluconeogenesis, Starch and sucrose metabolism 0.3211576 0.901
1779 insulin_signaling_h BioCarta H002553_01 Info Serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), H002553_01 M14083 82085 SERPINE1 Fibrinolysis Pathway, Platelet Amyloid Precursor Protein Pathway 0.3225313 0.914
1780 insulin_signaling_h BioCarta H003068_01 Info Pyruvate kinase, muscle H003068_01 M26252 198281 PKM2 Carbon fixation, Glycolysis / Gluconeogenesis, Purine metabolism, Pyruvate metabolism 0.3246109 1.102
1781 insulin_signaling_h BioCarta H003497_01 Info V-akt murine thymoma viral oncogene homolog 2 H003497_01 M77198 326445 AKT2 Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction, tsonc 0.3314111 0.872
1782 insulin_signaling_h BioCarta H000650_01 Info Glycogen synthase kinase 3 beta H000650_01 L33801 78802 GSK3B ALK in cardiac myocytes, Cell Cycle: G1/S Check Point , Deregulation of CDK5 in Alzheimer’s Disease, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Multi-step Regulation of Transcription by Pitx2, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Presenilin action in Notch and Wnt signaling, Regulation of eIF2, Segmentation Clock, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Sonic Hedgehog (Shh) Pathway, WNT Signaling Pathway, Phosphatidylinositol signaling system 0.353328 1.118
1783 insulin_signaling_h BioCarta H002509_01 Info D component of complement (adipsin) H002509_01 M84526 155597 DF immunology 0.3850381 0.93
1784 insulin_signaling_h BioCarta H013009_01 Info Adenylyl cyclase-associated protein H013009_01 L12168 104125 CAP 0.4133824 1.094
1785 insulin_signaling_h BioCarta H003579_01 Info TGFB inducible early growth response H003579_01 S81439 82173 TIEG angiogenesis, cell_cycle, cell_signaling, immunology, misc 0.431719 1.086
1786 insulin_signaling_h BioCarta H002624_01 Info Insulin receptor H002624_01 X02160 89695 INSR Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Growth Hormone Signaling Pathway, Insulin Signaling Pathway, immunology 0.433218 0.919
1787 insulin_signaling_h BioCarta H002698_01 Info Adrenergic, beta-3-, receptor H002698_01 NM_000025 2549 ADRB3 behavior, immunology 0.4399337 0.93
1788 insulin_signaling_h BioCarta H002085_01 Info Orosomucoid 1 H002085_01 X02544 572 ORM1 immunology 0.476851 1.07
1789 insulin_signaling_h BioCarta H002039_01 Info Phosphoenolpyruvate carboxykinase 2 (mitochondrial) H002039_01 X92720 75812 PCK2 Citrate cycle (TCA cycle), Pyruvate metabolism 0.4857451 0.932
1790 insulin_signaling_h BioCarta H007698_01 Info Eukaryotic translation initiation factor 4E binding protein 1 H007698_01 L36055 71819 EIF4EBP1 mTOR Signaling Pathway, Regulation of eIF4e and p70 S6 Kinase, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway 0.5191259 1.06
1791 insulin_signaling_h BioCarta H001952_01 Info Ribosomal protein L13a H001952_01 X56932 119122 RPL13A 0.565051 1.059
1792 insulin_signaling_h BioCarta H003538_01 Info Actin, beta H003538_01 NM_001101 288061 ACTB Chromatin Remodeling by hSWI/SNF ATP-dependent Complexes 0.6253266 0.956
1793 insulin_signaling_h BioCarta H003698_01 Info Protein tyrosine phosphatase, non-receptor type 1 H003698_01 M31724 155894 PTPN1 cell_cycle, cell_signaling 0.6633733 1.054
1794 insulin_signaling_h BioCarta H003612_01 Info V-akt murine thymoma viral oncogene homolog 1 H003612_01 M63167 71816 AKT1 Actions of Nitric Oxide in the Heart, AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, B Cell Survival Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia and p53 in the Cardiovascular system, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, mTOR Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Phospholipase C Signaling Pathway, Phospholipids as signaling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Ras Signaling Pathway, Regulation … 0.6741257 1.038
1795 insulin_signaling_h BioCarta H002722_01 Info Mitogen-activated protein kinase kinase 1 H002722_01 L11284 3446 MAP2K1 Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … 0.7377933 0.973
1796 insulin_signaling_h BioCarta H001045_01 Info Thyroglobulin H001045_01 X05615 305916 TG immunology 0.7668664 0.97
1797 insulin_signaling_h BioCarta H000245_01 Info Peroxisome proliferative activated receptor, gamma H000245_01 L40904 100724 PPARG Basic mechanism of action of PPARa, PPARb(d) and PPARg and effects on gene expression, Nuclear Receptors in Lipid Metabolism and Toxicity, Role of PPAR-gamma Coactivators in Obesity and Thermogenesis, Visceral Fat Deposits and the Metabolic Syndrome 0.7837641 0.944
1798 insulin_signaling_h BioCarta H003015_01 Info Excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes over H003015_01 M13194 59544 ERCC1 DNA_damage, DNA_replication, immunology 0.8177868 1.024
1799 insulin_signaling_h BioCarta H001596_01 Info Protein kinase C, gamma H001596_01 Z15114 2890 PRKCG Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.8498034 1.018
1800 insulin_signaling_h BioCarta H012856_01 Info MAP kinase-interacting serine/threonine kinase 1 H012856_01 AB000409 5591 MKNK1 Erk1/Erk2 Mapk Signaling pathway, MAP Kinase Signaling Pathway, mTOR Signaling Pathway, p38 MAPK Signaling Pathway , Regulation of eIF4e and p70 S6 Kinase, Phosphatidylinositol signaling system 0.9455231 0.992
1801 insulin_signaling_h BioCarta H015889_01 Info BCL2-like 1 H015889_01 NM_001191 305890 BCL2L1 Apoptotic Signaling in Response to DNA Damage, IL-2 Receptor Beta Chain in T cell Activation, Opposing roles of AIF in Apoptosis and Cell Survival, Ras Signaling Pathway, Regulation of BAD phosphorylation, Role of Mitochondria in Apoptotic Signaling, apoptosis, immunology 0.996743 1.001
1802 biopeptidesPathway_h Extracellular signaling peptides exert biological effects via G-protein coupled receptors (GPCRs), which activate intracellular GTPases. H002055_01 Info Growth factor receptor-bound protein 2 H002055_01 M96995 296381 GRB2 Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel … 0.0022348 1.459
1803 biopeptidesPathway_h Extracellular signaling peptides exert biological effects via G-protein coupled receptors (GPCRs), which activate intracellular GTPases. H002893_01 Info V-raf-1 murine leukemia viral oncogene homolog 1 H002893_01 X03484 85181 RAF1 Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … 0.0062484 1.596
1804 biopeptidesPathway_h Extracellular signaling peptides exert biological effects via G-protein coupled receptors (GPCRs), which activate intracellular GTPases. H003006_01 Info Serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 8 H003006_01 K02215 3697 SERPINA8 Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Angiotensin-converting enzyme 2 regulates heart function, Bioactive Peptide Induced Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, immunology 0.0063778 1.296
1805 biopeptidesPathway_h Extracellular signaling peptides exert biological effects via G-protein coupled receptors (GPCRs), which activate intracellular GTPases. H002895_01 Info Mitogen-activated protein kinase 14 H002895_01 L35263 79107 MAPK14 BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAP Kinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm … 0.0086925 1.429
1806 biopeptidesPathway_h Extracellular signaling peptides exert biological effects via G-protein coupled receptors (GPCRs), which activate intracellular GTPases. H002573_01 Info Protein tyrosine kinase 2 beta H002573_01 U43522 20313 PTK2B Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CXCR4 Signaling Pathway, IL-7 Signal Transduction, Ion Channel and Phorbol Esters Signaling Pathway, Links between Pyk2 and Map Kinases, Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Signaling of Hepatocyte Growth Factor Receptor, Thrombin signaling and protease-activated receptors, angiogenesis, immunology, signal_transduction 0.0091935 1.367
1807 biopeptidesPathway_h Extracellular signaling peptides exert biological effects via G-protein coupled receptors (GPCRs), which activate intracellular GTPases. H001365_01 Info Protein kinase C, beta 1 H001365_01 X07109 77202 PRKCB1 Bioactive Peptide Induced Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Ion Channel and Phorbol Esters Signaling Pathway, T Cell Receptor Signaling Pathway, Phosphatidylinositol signaling system, angiogenesis, cell_cycle, cell_signaling, signal_transduction 0.0304335 1.379
1808 biopeptidesPathway_h Extracellular signaling peptides exert biological effects via G-protein coupled receptors (GPCRs), which activate intracellular GTPases. H005657_01 Info Calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma H005657_01 L07044 250857 CAMK2G Bioactive Peptide Induced Signaling Pathway, Ca++/ Calmodulin-dependent Protein Kinase Activation, Regulation of PGC-1a, Stathmin and breast cancer resistance to antimicrotubule agents, Transcription factor CREB and its extracellular signals 0.0367532 1.297
1809 biopeptidesPathway_h Extracellular signaling peptides exert biological effects via G-protein coupled receptors (GPCRs), which activate intracellular GTPases. H003178_01 Info Mitogen-activated protein kinase 3 H003178_01 X60188 861 MAPK3 Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … 0.0986041 1.184
1810 biopeptidesPathway_h Extracellular signaling peptides exert biological effects via G-protein coupled receptors (GPCRs), which activate intracellular GTPases. H003158_01 Info Mitogen-activated protein kinase 8 H003158_01 L26318 190913 MAPK8 Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig … 0.1287835 1.166
1811 biopeptidesPathway_h Extracellular signaling peptides exert biological effects via G-protein coupled receptors (GPCRs), which activate intracellular GTPases. H012917_01 Info Homo sapiens clone 25048 mRNA sequence H012917_01 AF131776 321572 0.1524925 0.87
1812 biopeptidesPathway_h Extracellular signaling peptides exert biological effects via G-protein coupled receptors (GPCRs), which activate intracellular GTPases. H001649_01 Info Microtubule-associated protein tau H001649_01 NM_016835 101174 MAPT Bioactive Peptide Induced Signaling Pathway, Deregulation of CDK5 in Alzheimer’s Disease 0.2534636 1.111
1813 biopeptidesPathway_h Extracellular signaling peptides exert biological effects via G-protein coupled receptors (GPCRs), which activate intracellular GTPases. H000614_01 Info Guanine nucleotide binding protein (G protein), alpha 11 (Gq class) H000614_01 M69013 1686 GNA11 0.3060018 0.9
1814 biopeptidesPathway_h Extracellular signaling peptides exert biological effects via G-protein coupled receptors (GPCRs), which activate intracellular GTPases. H002405_01 Info Mitogen-activated protein kinase kinase 2 H002405_01 L11285 72241 MAP2K2 Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Bioactive Peptide Induced Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, fMLP induced chemokine gene expression in HMC-1 cells, Human Cytomegalovirus and Map Kinase Pathways, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Phosphorylation of MEK1 by cdk5/p35 down regulates the MAP kinase pathway, Role of MAL in Rho-Mediated Activation of SRF, Role of �-arrestins in the activation and targeting of MAP kinases, Roles of �-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling, Signaling of Hepatocyte Growth Factor Receptor 0.3118803 1.093
1815 biopeptidesPathway_h Extracellular signaling peptides exert biological effects via G-protein coupled receptors (GPCRs), which activate intracellular GTPases. H002329_01 Info Cyclin-dependent kinase 5 H002329_01 L04658 166071 CDK5 cell_cycle, cell_signaling, signal_transduction 0.3594933 0.914
1816 biopeptidesPathway_h Extracellular signaling peptides exert biological effects via G-protein coupled receptors (GPCRs), which activate intracellular GTPases. H011599_01 Info Homo sapiens mRNA; cDNA DKFZp434J194 (from clone DKFZp434J194) H011599_01 AL110227 323067 0.661501 0.954
1817 biopeptidesPathway_h Extracellular signaling peptides exert biological effects via G-protein coupled receptors (GPCRs), which activate intracellular GTPases. H000460_01 Info Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 H000460_01 AL049933 203862 GNAI1 Aspirin Blocks Signaling Pathway Involved in Platelet Activation, Bioactive Peptide Induced Signaling Pathway, CXCR4 Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Phospholipids as signaling intermediaries, Signaling Pathway from G-Protein Families, Thrombin signaling and protease-activated receptors, cell_signaling, signal_transduction 0.7235673 1.046
1818 biopeptidesPathway_h Extracellular signaling peptides exert biological effects via G-protein coupled receptors (GPCRs), which activate intracellular GTPases. H002722_01 Info Mitogen-activated protein kinase kinase 1 H002722_01 L11284 3446 MAP2K1 Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … 0.7377933 0.973
1819 biopeptidesPathway_h Extracellular signaling peptides exert biological effects via G-protein coupled receptors (GPCRs), which activate intracellular GTPases. H002404_01 Info Synaptotagmin I H002404_01 M55047 154679 SYT1 0.8170962 0.971
1820 biopeptidesPathway_h Extracellular signaling peptides exert biological effects via G-protein coupled receptors (GPCRs), which activate intracellular GTPases. H000579_01 Info Calmodulin 2 (phosphorylase kinase, delta) H000579_01 D45887 182278 CALM2 0.9689776 1.004
1821 ST_Ga13_Pathway_h Signalling Transduction KE H002186_01 Info Serum response factor (c-fos serum response element-binding transcription factor) H002186_01 J03161 155321 SRF EGF Signaling Pathway, Growth Hormone Signaling Pathway, Hop Pathway in Cardiac Development, IGF-1 Signaling Pathway, IL 6 signaling pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, cell_cycle, cell_signaling, development, gene_regulation, transcription 0.0017465 0.722
1822 ST_Ga13_Pathway_h Signalling Transduction KE H001360_01 Info Rho-associated, coiled-coil containing protein kinase 2 H001360_01 NM_004850 58617 ROCK2 CCR3 signaling in Eosinophils, Phosphatidylinositol signaling system 0.0029412 0.776
1823 ST_Ga13_Pathway_h Signalling Transduction KE H003611_01 Info Mitogen-activated protein kinase kinase 4 H003611_01 L36870 75217 MAP2K4 Perou’s – Intrinsic – Breast-Cancer-Genes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Ceramide Signaling Pathway, EGF Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, Inhibition of Cellular Proliferation by Gleevec, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , PDGF Signaling Pathway, T Cell Receptor Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system 0.012502 0.753
1824 ST_Ga13_Pathway_h Signalling Transduction KE H002188_01 Info Lipoprotein, Lp(a) H002188_01 X06290 119520 LPA immunology 0.0147871 0.763
1825 ST_Ga13_Pathway_h Signalling Transduction KE H006644_01 Info Phosphorylase kinase, alpha 2 (liver) H006644_01 X80497 54941 PHKA2 cell_cycle, cell_signaling, signal_transduction 0.0321533 1.233
1826 ST_Ga13_Pathway_h Signalling Transduction KE H016134_01 Info V-akt murine thymoma viral oncogene homolog 2 H016134_01 NM_001626 326445 AKT2 Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction, tsonc 0.0530988 1.287
1827 ST_Ga13_Pathway_h Signalling Transduction KE H003158_01 Info Mitogen-activated protein kinase 8 H003158_01 L26318 190913 MAPK8 Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig … 0.1287835 1.166
1828 ST_Ga13_Pathway_h Signalling Transduction KE H003550_01 Info Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) H003550_01 S76638 73090 NFKB2 gene_regulation, immunology, transcription, tsonc 0.1593331 1.165
1829 ST_Ga13_Pathway_h Signalling Transduction KE H003747_01 Info Serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 H003747_01 L19684 159628 SERPINA4 0.2081201 0.866
1830 ST_Ga13_Pathway_h Signalling Transduction KE H002112_01 Info PTK2 protein tyrosine kinase 2 H002112_01 L13616 740 PTK2 Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Apoptotic Signaling in Response to DNA Damage, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, CCR3 signaling in Eosinophils, Cell to Cell Adhesion Signaling, CXCR4 Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, HIV-I Nef: negative effector of Fas and TNF, Integrin Signaling Pathway, mCalpain and friends in Cell motility, Phospholipids as signaling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Signaling of Hepatocyte Growth Factor Receptor, Trefoil Factors Initiate Mucosal Healing, uCalpain and friends in Cell spread, VEGF, Hypoxia, and Angiogenesis, angiogenesis, signal_transduction 0.2346929 0.896
1831 ST_Ga13_Pathway_h Signalling Transduction KE H007827_01 Info Rho guanine exchange factor (GEF) 11 H007827_01 AB002378 47822 ARHGEF11 Rho cell motility signaling pathway 0.2493266 1.109
1832 ST_Ga13_Pathway_h Signalling Transduction KE H000042_01 Info Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma H000042_01 AF074382 43505 IKBKG CD40L Signaling Pathway, NF-kB Signaling Pathway, TNF/Stress Related Signaling, TNFR2 Signaling Pathway, Toll-Like Receptor Pathway 0.2784213 1.13
1833 ST_Ga13_Pathway_h Signalling Transduction KE H000220_01 Info Guanine nucleotide binding protein (G protein), alpha 13 H000220_01 L22075 1666 GNA13 PKC-catalyzed phosphorylation of inhibitory phosphoprotein of myosin phosphatase, Thrombin signaling and protease-activated receptors 0.2922764 1.182
1834 ST_Ga13_Pathway_h Signalling Transduction KE H003497_01 Info V-akt murine thymoma viral oncogene homolog 2 H003497_01 M77198 326445 AKT2 Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction, tsonc 0.3314111 0.872
1835 ST_Ga13_Pathway_h Signalling Transduction KE H003337_01 Info B-factor, properdin H003337_01 L15702 69771 BF Perou’s – Intrinsic – Breast-Cancer-Genes, immunology 0.3702495 1.093
1836 ST_Ga13_Pathway_h Signalling Transduction KE H005813_01 Info Phospholipase D2 H005813_01 AF038440 104519 PLD2 Metabolism of Anandamide, an Endogenous Cannabinoid, Glycerophospholipid metabolism 0.4846144 1.066
1837 ST_Ga13_Pathway_h Signalling Transduction KE H008413_01 Info Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 H008413_01 X77909 2764 NFKBIL1 0.5281661 1.058
1838 ST_Ga13_Pathway_h Signalling Transduction KE H002340_01 Info Mitogen-activated protein kinase kinase kinase 5 H002340_01 U67156 151988 MAP3K5 HIV-I Nef: negative effector of Fas and TNF, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , The 4-1BB-dependent immune response 0.5393151 1.07
1839 ST_Ga13_Pathway_h Signalling Transduction KE H001914_01 Info Phospholipase D1, phosphatidylcholine-specific H001914_01 U38545 82587 PLD1 Metabolism of Anandamide, an Endogenous Cannabinoid, Rac 1 cell motility signaling pathway, Ras Signaling Pathway, Glycerophospholipid metabolism 0.5637309 1.056
1840 ST_Ga13_Pathway_h Signalling Transduction KE H002198_01 Info Discs, large (Drosophila) homolog 4 H002198_01 U83192 23731 DLG4 Nitric Oxide Signaling Pathway, Synaptic Proteins at the Synaptic Junction 0.5763482 1.072
1841 ST_Ga13_Pathway_h Signalling Transduction KE H011529_01 Info Similar to vaccinia virus HindIII K4L ORF H011529_01 U60644 74573 HU-K4 Metabolism of Anandamide, an Endogenous Cannabinoid 0.5878171 1.054
1842 ST_Ga13_Pathway_h Signalling Transduction KE H002173_01 Info Cell division cycle 42 (GTP-binding protein, 25kD) H002173_01 AL121735 146409 CDC42 Agrin in Postsynaptic Differentiation, How does salmonella hijack a cell, p38 MAPK Signaling Pathway , Ras Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, cell_cycle, cell_signaling, signal_transduction 0.6486191 1.035
1843 ST_Ga13_Pathway_h Signalling Transduction KE H003612_01 Info V-akt murine thymoma viral oncogene homolog 1 H003612_01 M63167 71816 AKT1 Actions of Nitric Oxide in the Heart, AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, B Cell Survival Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia and p53 in the Cardiovascular system, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, mTOR Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Phospholipase C Signaling Pathway, Phospholipids as signaling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Ras Signaling Pathway, Regulation … 0.6741257 1.038
1844 ST_Ga13_Pathway_h Signalling Transduction KE H002447_01 Info Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha H002447_01 M69043 81328 NFKBIA Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Signal transduction through IL1R, T Cell Receptor Signaling Pathway, The 4-1BB-dependent immune … 0.8245205 0.975
1845 ST_Ga13_Pathway_h Signalling Transduction KE H003711_01 Info Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) H003711_01 M58603 83428 NFKB1 Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Bone Remodelling, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Ceramide Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Corticosteroids and cardioprotection, CXCR4 Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, Free Radical Induced Apoptosis, HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of a … 0.8665095 1.017
1846 ST_Dictyostelium_discoideum_cAMP_Chemotaxis_Pathway_h Signalling Transduction KE H001655_01 Info Grancalcin H001655_01 M81637 79381 GCL 0.0047006 1.807
1847 ST_Dictyostelium_discoideum_cAMP_Chemotaxis_Pathway_h Signalling Transduction KE H002704_01 Info Integrin, alpha 9 H002704_01 D25303 222 ITGA9 cell_signaling, metastasis 0.0133682 0.766
1848 ST_Dictyostelium_discoideum_cAMP_Chemotaxis_Pathway_h Signalling Transduction KE H004577_01 Info Vasodilator-stimulated phosphoprotein H004577_01 Z46389 93183 VASP cell_signaling, immunology, signal_transduction 0.0236006 1.288
1849 ST_Dictyostelium_discoideum_cAMP_Chemotaxis_Pathway_h Signalling Transduction KE H013335_01 Info Homo sapiens clone 24923 mRNA sequence H013335_01 AF131859 7037 0.0241253 1.215
1850 ST_Dictyostelium_discoideum_cAMP_Chemotaxis_Pathway_h Signalling Transduction KE H001348_01 Info Phosphoinositide-3-kinase, catalytic, delta polypeptide H001348_01 U86453 162808 PIK3CD Inositol phosphate metabolism, Phosphatidylinositol signaling system 0.0324563 1.426
1851 ST_Dictyostelium_discoideum_cAMP_Chemotaxis_Pathway_h Signalling Transduction KE H003628_01 Info Dystroglycan 1 (dystrophin-associated glycoprotein 1) H003628_01 L19711 76111 DAG1 Agrin in Postsynaptic Differentiation, immunology 0.034627 0.774
1852 ST_Dictyostelium_discoideum_cAMP_Chemotaxis_Pathway_h Signalling Transduction KE H000446_01 Info Proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) H000446_01 L07633 75348 PSME1 cell_signaling 0.0443091 1.231
1853 ST_Dictyostelium_discoideum_cAMP_Chemotaxis_Pathway_h Signalling Transduction KE H001620_01 Info Diacylglycerol kinase, alpha (80kD) H001620_01 X62535 172690 DGKA Glycerolipid metabolism, Glycerophospholipid metabolism, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.0809489 1.164
1854 ST_Dictyostelium_discoideum_cAMP_Chemotaxis_Pathway_h Signalling Transduction KE H003178_01 Info Mitogen-activated protein kinase 3 H003178_01 X60188 861 MAPK3 Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … 0.0986041 1.184
1855 ST_Dictyostelium_discoideum_cAMP_Chemotaxis_Pathway_h Signalling Transduction KE H002287_01 Info P21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related) H002287_01 U24152 62402 PAK1 Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, FAS signaling pathway ( CD95 ), fMLP induced chemokine gene expression in HMC-1 cells, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Rac 1 cell motility signaling pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, TNFR1 Signaling Pathway 0.1104284 0.815
1856 ST_Dictyostelium_discoideum_cAMP_Chemotaxis_Pathway_h Signalling Transduction KE H001748_01 Info Inositol 1,4,5-trisphosphate 3-kinase B H001748_01 X57206 78877 ITPKB Inositol phosphate metabolism, Phosphatidylinositol signaling system, cell_signaling, signal_transduction 0.1283627 0.851
1857 ST_Dictyostelium_discoideum_cAMP_Chemotaxis_Pathway_h Signalling Transduction KE H001718_01 Info Inositol 1,4,5-trisphosphate 3-kinase A H001718_01 X54938 2722 ITPKA Inositol phosphate metabolism, Phosphatidylinositol signaling system 0.1331494 1.16
1858 ST_Dictyostelium_discoideum_cAMP_Chemotaxis_Pathway_h Signalling Transduction KE H016038_01 Info Pallid (mouse) homolog, pallidin H016038_01 BC004819 317714 PA 0.3260679 1.082
1859 ST_Dictyostelium_discoideum_cAMP_Chemotaxis_Pathway_h Signalling Transduction KE H003337_01 Info B-factor, properdin H003337_01 L15702 69771 BF Perou’s – Intrinsic – Breast-Cancer-Genes, immunology 0.3702495 1.093
1860 ST_Dictyostelium_discoideum_cAMP_Chemotaxis_Pathway_h Signalling Transduction KE H000897_01 Info Inositol 1,4,5-triphosphate receptor, type 2 H000897_01 D26350 238272 ITPR2 0.5011337 1.061
1861 ST_Dictyostelium_discoideum_cAMP_Chemotaxis_Pathway_h Signalling Transduction KE H003612_01 Info V-akt murine thymoma viral oncogene homolog 1 H003612_01 M63167 71816 AKT1 Actions of Nitric Oxide in the Heart, AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, B Cell Survival Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia and p53 in the Cardiovascular system, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, mTOR Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Phospholipase C Signaling Pathway, Phospholipids as signaling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Ras Signaling Pathway, Regulation … 0.6741257 1.038
1862 ST_Dictyostelium_discoideum_cAMP_Chemotaxis_Pathway_h Signalling Transduction KE H002722_01 Info Mitogen-activated protein kinase kinase 1 H002722_01 L11284 3446 MAP2K1 Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … 0.7377933 0.973
1863 ST_Dictyostelium_discoideum_cAMP_Chemotaxis_Pathway_h Signalling Transduction KE H010993_01 Info Electron-transfer-flavoprotein, alpha polypeptide (glutaric aciduria II) H010993_01 J04058 169919 ETFA Perou’s – Intrinsic – Breast-Cancer-Genes 0.7904014 0.968
1864 ST_Dictyostelium_discoideum_cAMP_Chemotaxis_Pathway_h Signalling Transduction KE H013182_01 Info ARP2 (actin-related protein 2, yeast) homolog H013182_01 AF006082 42915 ACTR2 0.840062 0.978
1865 ST_Dictyostelium_discoideum_cAMP_Chemotaxis_Pathway_h Signalling Transduction KE H011434_01 Info ARP3 (actin-related protein 3, yeast) homolog H011434_01 NM_005721 5321 ACTR3 0.8741333 1.017
1866 ST_Dictyostelium_discoideum_cAMP_Chemotaxis_Pathway_h Signalling Transduction KE H012065_01 Info Ribosomal protein S4, X-linked H012065_01 M58458 108124 RPS4X immunology 0.8900601 1.017
1867 ST_Dictyostelium_discoideum_cAMP_Chemotaxis_Pathway_h Signalling Transduction KE H007337_01 Info Inositol 1,4,5-triphosphate receptor, type 3 H007337_01 U01062 77515 ITPR3 0.8999809 0.984
1868 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002227_01 Info Integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B) H002227_01 NM_000419 785 ITGA2B immunology 0.0006863 1.674
1869 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002931_01 Info Selectin L (lymphocyte adhesion molecule 1) H002931_01 M25280 82848 SELL Adhesion and Diapedesis of Granulocytes, Adhesion and Diapedesis of Lymphocytes, Adhesion Molecules on Lymphocyte, Monocyte and its Surface Molecules, Neutrophil and Its Surface Molecules, cell_signaling, immunology, metastasis 0.0013165 2.024
1870 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002552_01 Info Integrin beta 3 binding protein (beta3-endonexin) H002552_01 U37139 82084 ITGB3BP 0.0013566 0.728
1871 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002398_01 Info CD22 antigen H002398_01 X59350 171763 CD22 angiogenesis, immunology, metastasis 0.0039052 1.468
1872 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H000396_01 Info Fasciculation and elongation protein zeta 1 (zygin I) H000396_01 U60060 79226 FEZ1 0.0041715 0.684
1873 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H006226_01 Info Protein tyrosine phosphatase, non-receptor type substrate 1 H006226_01 AB023430 156114 PTPNS1 0.0082221 1.447
1874 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H004690_01 Info G protein-coupled receptor 56 H004690_01 AJ011001 6527 GPR56 0.0090947 0.782
1875 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H003139_01 Info Integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 H003139_01 M15395 83968 ITGB2 Adhesion and Diapedesis of Granulocytes, Adhesion and Diapedesis of Lymphocytes, Adhesion Molecules on Lymphocyte, B Lymphocyte Cell Surface Molecules, Cells and Molecules involved in local acute inflammatory response, CTL mediated immune response against target cells , Monocyte and its Surface Molecules, Neutrophil and Its Surface Molecules, T Cytotoxic Cell Surface Molecules, T Helper Cell Surface Molecules, cell_signaling, immunology, metastasis 0.0091308 1.578
1876 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002573_01 Info Protein tyrosine kinase 2 beta H002573_01 U43522 20313 PTK2B Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CXCR4 Signaling Pathway, IL-7 Signal Transduction, Ion Channel and Phorbol Esters Signaling Pathway, Links between Pyk2 and Map Kinases, Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Signaling of Hepatocyte Growth Factor Receptor, Thrombin signaling and protease-activated receptors, angiogenesis, immunology, signal_transduction 0.0091935 1.367
1877 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002944_01 Info Interleukin 8 H002944_01 M17017 624 IL8 Adhesion and Diapedesis of Granulocytes, Adhesion and Diapedesis of Lymphocytes, Cells and Molecules involved in local acute inflammatory response, Cytokine Network, Cytokines and Inflammatory Response, Free Radical Induced Apoptosis, IL 17 Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Proepithelin Conversion to Epithelin and Wound Repair Control, Regulation of hematopoiesis by cytokines, immunology 0.0100881 0.681
1878 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H001984_01 Info Hyaluronan-binding protein 2 H001984_01 D49742 241363 HABP2 0.0120275 0.727
1879 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002233_01 Info Selectin P ligand H002233_01 NM_003006 79283 SELPLG Adhesion and Diapedesis of Granulocytes, Cells and Molecules involved in local acute inflammatory response, angiogenesis, immunology, metastasis 0.0126025 1.69
1880 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002704_01 Info Integrin, alpha 9 H002704_01 D25303 222 ITGA9 cell_signaling, metastasis 0.0133682 0.766
1881 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002955_01 Info Discoidin domain receptor family, member 1 H002955_01 NM_013994 75562 DDR1 0.0169265 0.724
1882 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002921_01 Info CD33 antigen (gp67) H002921_01 M23197 83731 CD33 Dendritic cells in regulating TH1 and TH2 Development, angiogenesis, metastasis 0.0177347 1.324
1883 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H003049_01 Info Integrin, alpha X (antigen CD11C (p150), alpha polypeptide) H003049_01 M81695 51077 ITGAX Dendritic cells in regulating TH1 and TH2 Development, cell_signaling, immunology, metastasis 0.0199733 1.464
1884 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002134_01 Info Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (se H002134_01 U60800 79089 SEMA4D 0.0210381 1.307
1885 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002661_01 Info Egf-like module containing, mucin-like, hormone receptor-like sequence 1 H002661_01 X81479 2375 EMR1 0.0264536 1.293
1886 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H006288_01 Info AE-binding protein 1 H006288_01 AF053944 118397 AEBP1 0.0298793 0.787
1887 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H000986_01 Info Glycoprotein IX (platelet) H000986_01 X52997 1144 GP9 immunology 0.0311848 1.262
1888 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002243_01 Info Ras homolog gene family, member E H002243_01 S82240 6838 ARHE immunology 0.032366 1.421
1889 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H003546_01 Info Integrin, alpha 5 (fibronectin receptor, alpha polypeptide) H003546_01 X06256 149609 ITGA5 cell_signaling, immunology, metastasis 0.0363906 1.254
1890 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H013467_01 Info Claudin 10 H013467_01 U89916 26126 CLDN10 0.0518009 0.837
1891 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H003719_01 Info Integrin, beta 7 H003719_01 M68892 1741 ITGB7 cell_signaling, immunology, metastasis 0.0529984 0.815
1892 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H001223_01 Info Sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and sh H001223_01 U52840 27621 SEMA5A 0.0591735 0.853
1893 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H003051_01 Info Neural cell adhesion molecule 1 H003051_01 S71824 167988 NCAM1 Synaptic Proteins at the Synaptic Junction, cell_signaling, immunology, metastasis 0.0668517 1.161
1894 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H005433_01 Info Claudin 1 H005433_01 AF134160 7327 CLDN1 0.0719995 0.772
1895 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H012084_01 Info Contactin 6 H012084_01 AB003592 109050 CNTN6 0.0825203 1.155
1896 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H001954_01 Info Milk fat globule-EGF factor 8 protein H001954_01 U58516 3745 MFGE8 Perou’s – Intrinsic – Breast-Cancer-Genes 0.082982 0.826
1897 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H008629_01 Info Spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive) H008629_01 Y16610 296847 SPG7 Perou’s – Intrinsic – Breast-Cancer-Genes 0.103499 1.154
1898 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H003524_01 Info Vitronectin (serum spreading factor, somatomedin B, complement S-protein) H003524_01 X03168 2257 VTN angiogenesis, immunology, misc 0.1100276 0.835
1899 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H011697_01 Info Bystin-like H011697_01 L36720 106880 BYSL 0.1129454 0.796
1900 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H001908_01 Info Discoidin domain receptor family, member 2 H001908_01 X74764 71891 DDR2 0.1167676 0.839
1901 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H009546_01 Info Small EDRK-rich factor 2 H009546_01 NM_005770 323806 SERF2 0.120338 1.195
1902 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H003899_01 Info Chemokine (C-C motif) receptor 1 H003899_01 D10925 301921 CCR1 Selective expression of chemokine receptors during T-cell polarization, immunology 0.1258208 1.15
1903 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002937_01 Info Fibronectin 1 H002937_01 X02761 287820 FN1 angiogenesis, cell_signaling, immunology, metastasis 0.128354 1.194
1904 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002990_01 Info Cadherin 8, type 2 H002990_01 AB035305 79133 CDH8 0.1344667 0.864
1905 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H000087_01 Info Transforming growth factor beta 1 induced transcript 1 H000087_01 AB007836 25511 TGFB1I1 0.1561907 1.139
1906 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H015048_01 Info Protocadherin beta 3 H015048_01 NM_018937 283086 PCDHB3 0.1614222 0.865
1907 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H008391_01 Info Plakophilin 4 H008391_01 X81889 152151 PKP4 0.1673938 1.162
1908 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H006236_01 Info Coagulation factor VIII, procoagulant component (hemophilia A) H006236_01 M90707 79345 F8 Intrinsic Prothrombin Activation Pathway 0.1700597 0.828
1909 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002555_01 Info Junction plakoglobin H002555_01 Z68228 2340 JUP immunology 0.1776342 0.877
1910 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H005908_01 Info Flotillin 2 H005908_01 M60922 184488 FLOT2 Perou’s – Intrinsic – Breast-Cancer-Genes 0.179195 1.18
1911 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002501_01 Info Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) H002501_01 D25274 173737 RAC1 Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, fMLP induced chemokine gene expression in HMC-1 cells, How does salmonella hijack a cell, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , Phosphoinositides and their downstream targets., Phospholipids as signaling intermediaries, Rac 1 cell motility signaling pathway, Ras Signaling Pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of MAL in Rho-Mediated Activation of SRF, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, T Cell Receptor Signaling Pathway, Transcription factor CREB and its extracellular signals, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, uCalpain and friends in Cell spread, Y branching of actin filaments 0.1980127 1.118
1912 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H000520_01 Info Cell adhesion molecule with homology to L1CAM (close homologue of L1) H000520_01 AF002246 210863 CHL1 0.2072085 0.87
1913 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002477_01 Info Neogenin (chicken) homolog 1 H002477_01 U61262 90408 NEO1 angiogenesis, metastasis 0.2084414 1.135
1914 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H003818_01 Info Ectonucleoside triphosphate diphosphohydrolase 1 H003818_01 AJ133133 205353 ENTPD1 Purine metabolism, Pyrimidine metabolism 0.2115941 1.145
1915 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H001101_01 Info CD164 antigen, sialomucin H001101_01 D14043 43910 CD164 0.2123692 0.89
1916 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002456_01 Info Cadherin 4, type 1, R-cadherin (retinal) H002456_01 L34059 89484 CDH4 cell_signaling, metastasis 0.213629 0.879
1917 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H010955_01 Info Peanut (Drosophila)-like 1 H010955_01 U74628 3847 PNUTL1 immunology 0.2330497 1.154
1918 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H001382_01 Info Calcium/calmodulin-dependent serine protein kinase (MAGUK family) H001382_01 AF035582 151469 CASK Synaptic Proteins at the Synaptic Junction 0.2450624 0.894
1919 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H011988_01 Info Mucosal vascular addressin cell adhesion molecule 1 H011988_01 U43628 102598 MADCAM1 Adhesion and Diapedesis of Lymphocytes 0.2675057 1.096
1920 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002337_01 Info Stromal cell-derived factor 1 H002337_01 L36033 237356 SDF1 CXCR4 Signaling Pathway, Pertussis toxin-insensitive CCR5 Signaling in Macrophage 0.2981205 1.118
1921 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H015755_01 Info Chemokine (C-C motif) receptor 1 H015755_01 NM_001295 301921 CCR1 Selective expression of chemokine receptors during T-cell polarization, immunology 0.3366567 1.129
1922 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H008328_01 Info Endothelial differentiation, sphingolipid G-protein-coupled receptor, 1 H008328_01 AF233365 154210 EDG1 Phospholipids as signaling intermediaries, immunology 0.3391872 0.905
1923 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H005782_01 Info Retinoschisis (X-linked, juvenile) 1 H005782_01 AF014459 113250 RS1 0.3512019 1.069
1924 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002557_01 Info Protein tyrosine phosphatase, receptor type, U H002557_01 X97198 19718 PTPRU 0.3521897 1.092
1925 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H003699_01 Info Chondroitin sulfate proteoglycan 2 (versican) H003699_01 U16306 81800 CSPG2 immunology 0.3780363 0.892
1926 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H006685_01 Info Macrophage erythroblast attacher H006685_01 AK001088 20815 MAEA 0.4159192 1.104
1927 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H011069_01 Info Nephrosis 1, congenital, Finnish type (nephrin) H011069_01 AF035835 190311 NPHS1 0.4304362 1.087
1928 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002976_01 Info G protein-coupled receptor 9 H002976_01 X95876 198252 GPR9 IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, mCalpain and friends in Cell motility, NO2-dependent IL 12 Pathway in NK cells, Selective expression of chemokine receptors during T-cell polarization 0.4390046 0.918
1929 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H011423_01 Info C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 6 H011423_01 AJ133532 115515 CLECSF6 0.4493538 1.095
1930 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H001943_01 Info CD58 antigen, (lymphocyte function-associated antigen 3) H001943_01 Y00636 75626 CD58 IL 17 Signaling Pathway, cell_signaling, immunology, metastasis 0.4535251 0.932
1931 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002328_01 Info Integrin, alpha M (complement component receptor 3, alpha; also known as CD11b (p170), macrophage an H002328_01 J03925 172631 ITGAM Adhesion and Diapedesis of Granulocytes, Monocyte and its Surface Molecules, Neutrophil and Its Surface Molecules, cell_signaling, immunology, metastasis 0.4578639 0.936
1932 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H001175_01 Info Lutheran blood group (Auberger b antigen included) H001175_01 X83425 155048 LU Perou’s – Intrinsic – Breast-Cancer-Genes, immunology 0.4765592 1.07
1933 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H004192_01 Info Homo sapiens mRNA; cDNA DKFZp566E103 (from clone DKFZp566E103) H004192_01 AL050053 227397 Synaptic Proteins at the Synaptic Junction, cell_signaling, immunology, metastasis 0.4769586 0.93
1934 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H010984_01 Info Contactin associated protein 1 H010984_01 U87223 31622 CNTNAP1 0.4850281 0.941
1935 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002035_01 Info FAT tumor suppressor (Drosophila) homolog H002035_01 X87241 166994 FAT cell_signaling, immunology, metastasis, tsonc 0.4989072 0.922
1936 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H010407_01 Info Adhesion glycoprotein H010407_01 U56102 57699 DNAM-1 0.5470565 0.946
1937 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H003424_01 Info Chemokine (C-C motif) receptor 3 H003424_01 U28694 158324 CCR3 CCR3 signaling in Eosinophils, IL 5 Signaling Pathway, Selective expression of chemokine receptors during T-cell polarization, The Role of Eosinophils in the Chemokine Network of Allergy, immunology 0.5671442 1.138
1938 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H003454_01 Info Integrin, beta 6 H003454_01 M35198 123125 ITGB6 immunology 0.6028747 1.064
1939 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H001310_01 Info Natural killer cell transcript 4 H001310_01 M59807 943 NK4 0.6125553 1.066
1940 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H012881_01 Info Homo sapiens cDNA FLJ20843 fis, clone ADKA01954 H012881_01 AK000850 272203 0.6176754 1.054
1941 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H006635_01 Info Homo sapiens clone 23607 mRNA sequence H006635_01 AF038181 167825 ALK in cardiac myocytes, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Multi-step Regulation of Transcription by Pitx2, Presenilin action in Notch and Wnt signaling, TGF beta signaling pathway, WNT Signaling Pathway, development, immunology, tsonc 0.6181322 1.041
1942 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H013889_01 Info SEEK1 protein H013889_01 AB031479 91600 SEEK1 0.6212047 1.057
1943 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H000279_01 Info Leupaxin H000279_01 AF062075 49587 LPXN 0.6381623 1.046
1944 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002570_01 Info Interleukin 2 H002570_01 S82692 89679 IL2 Antigen Dependent B Cell Activation, Cytokine Network, Cytokines and Inflammatory Response, IL 18 Signaling Pathway, IL 2 signaling pathway, OX40 Signaling Pathway, Regulation of hematopoiesis by cytokines, Role of Tob in T-cell activation, Selective expression of chemokine receptors during T-cell polarization, Th1/Th2 Differentiation, The 4-1BB-dependent immune response, The Co-Stimulatory Signal During T-cell Activation, immunology 0.6483346 1.043
1945 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H000757_01 Info Calcium and integrin binding protein (DNA-dependent protein kinase interacting protein) H000757_01 U85611 10803 SIP2-28 0.6487041 0.959
1946 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H001985_01 Info RAB13, member RAS oncogene family H001985_01 X75593 151536 RAB13 tsonc 0.6547022 0.954
1947 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H005759_01 Info Vinexin beta (SH3-containing adaptor molecule-1) H005759_01 AF037261 33787 SCAM-1 0.6677983 0.927
1948 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002380_01 Info Chemokine (C-C motif) receptor 8 H002380_01 D49919 113222 CCR8 immunology 0.6915296 1.035
1949 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002212_01 Info Zyxin H002212_01 X95735 75873 ZYX Integrin Signaling Pathway 0.7015822 1.041
1950 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002425_01 Info CD2 antigen (p50), sheep red blood cell receptor H002425_01 M16336 89476 CD2 Dendritic cells in regulating TH1 and TH2 Development, IL 17 Signaling Pathway, NO2-dependent IL 12 Pathway in NK cells, Stathmin and breast cancer resistance to antimicrotubule agents, T Cytotoxic Cell Surface Molecules, T Helper Cell Surface Molecules, angiogenesis, immunology, metastasis 0.7161918 1.064
1951 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002317_01 Info Chemokine (C-X3-C) receptor 1 H002317_01 U20350 78913 CX3CR1 immunology 0.7275779 1.038
1952 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H007610_01 Info Myeloid/lymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog); translocated to, 4 H007610_01 AB016898 100469 MLLT4 misc 0.7354494 0.972
1953 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H005451_01 Info Integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) H005451_01 S70348 87149 ITGB3 Phospholipids as signaling intermediaries, uCalpain and friends in Cell spread, cell_signaling, immunology, metastasis 0.7730219 1.027
1954 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002330_01 Info Cadherin 15, M-cadherin (myotubule) H002330_01 D83542 148090 CDH15 0.7996949 0.974
1955 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H006776_01 Info Tetraspan 1 H006776_01 AF065388 38972 TSPAN-1 0.819954 1.022
1956 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H003407_01 Info Von Willebrand factor H003407_01 X04385 110802 VWF angiogenesis, immunology, misc 0.8290575 1.021
1957 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H009708_01 Info Cell recognition molecule Caspr2 H009708_01 NM_014141 106552 KIAA0868 0.8379152 1.017
1958 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H001286_01 Info Myeloid/lymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog); translocated to, 4 H001286_01 AL161973 100469 MLLT4 misc 0.8547896 1.027
1959 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002490_01 Info Hexabrachion (tenascin C, cytotactin) H002490_01 X78565 289114 HXB Perou’s – Intrinsic – Breast-Cancer-Genes 0.856155 0.983
1960 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H005864_01 Info Immunoglobulin superfamily, member 1 H005864_01 AB002362 22111 IGSF1 0.8881091 0.983
1961 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002891_01 Info Small inducible cytokine A4 (homologous to mouse Mip-1b) H002891_01 J04130 75703 SCYA4 Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Selective expression of chemokine receptors during T-cell polarization 0.8975649 1.014
1962 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H004275_01 Info Elastin microfibril interface located protein H004275_01 AL050138 63348 EMILIN 0.8986492 1.013
1963 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H011503_01 Info Integrin, beta-like 1 (with EGF-like repeat domains) H011503_01 AF072752 82582 ITGBL1 angiogenesis 0.9588704 0.995
1964 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H009310_01 Info Immunoglobulin superfamily containing leucine-rich repeat H009310_01 AB024536 102171 ISLR 0.9743631 0.997
1965 ceramidePathway_h Ceramide is a lipid signaling molecule that can activate proliferative or apoptotic pathways, depending on signaling context, localization, and cell type. H002893_01 Info V-raf-1 murine leukemia viral oncogene homolog 1 H002893_01 X03484 85181 RAF1 Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … 0.0062484 1.596
1966 ceramidePathway_h Ceramide is a lipid signaling molecule that can activate proliferative or apoptotic pathways, depending on signaling context, localization, and cell type. H000877_01 Info Sphingomyelin phosphodiesterase 1, acid lysosomal (acid sphingomyelinase) H000877_01 X59960 77813 SMPD1 Ceramide Signaling Pathway, Glycosphingolipid metabolism 0.0075987 1.354
1967 ceramidePathway_h Ceramide is a lipid signaling molecule that can activate proliferative or apoptotic pathways, depending on signaling context, localization, and cell type. H003611_01 Info Mitogen-activated protein kinase kinase 4 H003611_01 L36870 75217 MAP2K4 Perou’s – Intrinsic – Breast-Cancer-Genes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Ceramide Signaling Pathway, EGF Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, Inhibition of Cellular Proliferation by Gleevec, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , PDGF Signaling Pathway, T Cell Receptor Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system 0.012502 0.753
1968 ceramidePathway_h Ceramide is a lipid signaling molecule that can activate proliferative or apoptotic pathways, depending on signaling context, localization, and cell type. H003178_01 Info Mitogen-activated protein kinase 3 H003178_01 X60188 861 MAPK3 Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … 0.0986041 1.184
1969 ceramidePathway_h Ceramide is a lipid signaling molecule that can activate proliferative or apoptotic pathways, depending on signaling context, localization, and cell type. H002786_01 Info Caspase 8, apoptosis-related cysteine protease H002786_01 X98172 19949 CASP8 Caspase Cascade in Apoptosis, Ceramide Signaling Pathway, D4-GDI Signaling Pathway, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Role of Mitochondria in Apoptotic Signaling, SODD/TNFR1 Signaling Pathway, TNFR1 Signaling Pathway, apoptosis, immunology 0.1208497 1.128
1970 ceramidePathway_h Ceramide is a lipid signaling molecule that can activate proliferative or apoptotic pathways, depending on signaling context, localization, and cell type. H003158_01 Info Mitogen-activated protein kinase 8 H003158_01 L26318 190913 MAPK8 Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig … 0.1287835 1.166
1971 ceramidePathway_h Ceramide is a lipid signaling molecule that can activate proliferative or apoptotic pathways, depending on signaling context, localization, and cell type. H003605_01 Info BCL2-associated X protein H003605_01 L22474 159428 BAX Apoptotic Signaling in Response to DNA Damage, Ceramide Signaling Pathway, Hypoxia and p53 in the Cardiovascular system, p53 Signaling Pathway, Regulation of BAD phosphorylation, Role of Mitochondria in Apoptotic Signaling, apoptosis, development, immunology 0.253339 0.907
1972 ceramidePathway_h Ceramide is a lipid signaling molecule that can activate proliferative or apoptotic pathways, depending on signaling context, localization, and cell type. H006662_01 Info Fas (TNFRSF6)-associated via death domain H006662_01 X84709 86131 FADD Perou’s – Intrinsic – Breast-Cancer-Genes, Acetylation and Deacetylation of RelA in The Nucleus, Ceramide Signaling Pathway, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , NF-kB Signaling Pathway, SODD/TNFR1 Signaling Pathway, TNFR1 Signaling Pathway, immunology 0.292449 1.108
1973 ceramidePathway_h Ceramide is a lipid signaling molecule that can activate proliferative or apoptotic pathways, depending on signaling context, localization, and cell type. H002660_01 Info TNFRSF1A-associated via death domain H002660_01 L41690 89862 TRADD Acetylation and Deacetylation of RelA in The Nucleus, Ceramide Signaling Pathway, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , MAP Kinase Signaling Pathway, NF-kB Signaling Pathway, p38 MAPK Signaling Pathway , SODD/TNFR1 Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway 0.3157474 1.092
1974 ceramidePathway_h Ceramide is a lipid signaling molecule that can activate proliferative or apoptotic pathways, depending on signaling context, localization, and cell type. H000028_01 Info Programmed cell death 8 (apoptosis-inducing factor) H000028_01 AL049703 18720 PDCD8 Ceramide Signaling Pathway, Opposing roles of AIF in Apoptosis and Cell Survival, Role of Mitochondria in Apoptotic Signaling 0.3727024 0.894
1975 ceramidePathway_h Ceramide is a lipid signaling molecule that can activate proliferative or apoptotic pathways, depending on signaling context, localization, and cell type. H000025_01 Info Neutral sphingomyelinase (N-SMase) activation associated factor H000025_01 X96586 78687 NSMAF Ceramide Signaling Pathway 0.5133585 0.948
1976 ceramidePathway_h Ceramide is a lipid signaling molecule that can activate proliferative or apoptotic pathways, depending on signaling context, localization, and cell type. H001974_01 Info BCL2-antagonist of cell death H001974_01 U66879 76366 BAD AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, Ceramide Signaling Pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Phosphoinositides and their downstream targets., Ras Signaling Pathway, Regulation of BAD phosphorylation, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Trefoil Factors Initiate Mucosal Healing, apoptosis, development 0.6985187 0.954
1977 ceramidePathway_h Ceramide is a lipid signaling molecule that can activate proliferative or apoptotic pathways, depending on signaling context, localization, and cell type. H002722_01 Info Mitogen-activated protein kinase kinase 1 H002722_01 L11284 3446 MAP2K1 Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … 0.7377933 0.973
1978 ceramidePathway_h Ceramide is a lipid signaling molecule that can activate proliferative or apoptotic pathways, depending on signaling context, localization, and cell type. H006841_01 Info Homo sapiens mRNA; cDNA DKFZp564P073 (from clone DKFZp564P073) H006841_01 AL049301 278577 Apoptotic Signaling in Response to DNA Damage, Ceramide Signaling Pathway, Hypoxia and p53 in the Cardiovascular system, p53 Signaling Pathway, Regulation of BAD phosphorylation, Role of Mitochondria in Apoptotic Signaling, apoptosis, development, immunology 0.7810094 0.98
1979 ceramidePathway_h Ceramide is a lipid signaling molecule that can activate proliferative or apoptotic pathways, depending on signaling context, localization, and cell type. H003711_01 Info Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) H003711_01 M58603 83428 NFKB1 Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Bone Remodelling, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Ceramide Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Corticosteroids and cardioprotection, CXCR4 Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, Free Radical Induced Apoptosis, HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of a … 0.8665095 1.017
1980 ceramidePathway_h Ceramide is a lipid signaling molecule that can activate proliferative or apoptotic pathways, depending on signaling context, localization, and cell type. H002963_01 Info V-rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide H00 2963_01L19067 75569 RELA Acetylation and Deacetylation of RelA in The Nucleus, Erythropoietin mediated neuroprotection through NF-kB, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, immunology, tsonc 0.9724165 1.003
1981 eea1Pathway_h The FYVE-finger proteins EEA1 and HRS are localized to endosome membranes and regulate sorting and ubiquitination in the vesicle transport system. H003000_01 Info RAB5A, member RAS oncogene family H003000_01 M28215 73957 RAB5A Phosphoinositides and their downstream targets., Rab GTPases Mark Targets In The Endocytotic Machinery, The role of FYVE-finger proteins in vesicle transport, tsonc 0.0003278 0.591
1982 eea1Pathway_h The FYVE-finger proteins EEA1 and HRS are localized to endosome membranes and regulate sorting and ubiquitination in the vesicle transport system. H002040_01 Info Epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog) H002040_01 X00588 77432 EGFR Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Keratinocyte Differentiation, Map Kinase Inactivation of SMRT Corepressor, mCalpain and friends in Cell motility, Neuroregulin receptor degradation protein-1 Controls ErbB3 receptor recycling, Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Role of ERBB2 in Signal Transduction and Oncology, Sprouty regulation of tyrosine kinase signals, Telomeres, Telomerase, Cellular Aging, and Immortality, The role of FYVE-finger proteins in vesicle transport, Trefoil Factors Initiate Mucosal Healing, angiogenesis, signal_transduction, tsonc 0.0004362 0.669
1983 eea1Pathway_h The FYVE-finger proteins EEA1 and HRS are localized to endosome membranes and regulate sorting and ubiquitination in the vesicle transport system. H001590_01 Info Early endosome antigen 1, 162kD H001590_01 L40157 2864 EEA1 Phosphoinositides and their downstream targets., The role of FYVE-finger proteins in vesicle transport 0.0683087 0.8
1984 eea1Pathway_h The FYVE-finger proteins EEA1 and HRS are localized to endosome membranes and regulate sorting and ubiquitination in the vesicle transport system. H002682_01 Info Transferrin H002682_01 S95936 284176 TF The role of FYVE-finger proteins in vesicle transport, immunology 0.5663067 0.93
1985 eea1Pathway_h The FYVE-finger proteins EEA1 and HRS are localized to endosome membranes and regulate sorting and ubiquitination in the vesicle transport system. H000655_01 Info Hepatocyte growth factor-regulated tyrosine kinase substrate H000655_01 U43895 24756 HGS The role of FYVE-finger proteins in vesicle transport 0.7645593 1.024
1986 eea1Pathway_h The FYVE-finger proteins EEA1 and HRS are localized to endosome membranes and regulate sorting and ubiquitination in the vesicle transport system. H015257_01 Info Transferrin H015257_01 NM_001063 284176 TF The role of FYVE-finger proteins in vesicle transport, immunology 0.860187 1.017
1987 eea1Pathway_h The FYVE-finger proteins EEA1 and HRS are localized to endosome membranes and regulate sorting and ubiquitination in the vesicle transport system. H002993_01 Info Transferrin receptor (p90, CD71) H002993_01 X01060 77356 TFRC The role of FYVE-finger proteins in vesicle transport, immunology 0.9856571 1.002
1988 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H002055_01 Info Growth factor receptor-bound protein 2 H002055_01 M96995 296381 GRB2 Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel … 0.0022348 1.459
1989 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H002893_01 Info V-raf-1 murine leukemia viral oncogene homolog 1 H002893_01 X03484 85181 RAF1 Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … 0.0062484 1.596
1990 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H002878_01 Info V-yes-1 Yamaguchi sarcoma viral related oncogene homolog H002878_01 M16038 80887 LYN BCR Signaling Pathway, Eph Kinases and ephrins support platelet aggregation, Fc Epsilon Receptor I Signaling in Mast Cells, Phosphoinositides and their downstream targets., immunology, signal_transduction, tsonc 0.0068841 1.545
1991 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H001348_01 Info Phosphoinositide-3-kinase, catalytic, delta polypeptide H001348_01 U86453 162808 PIK3CD Inositol phosphate metabolism, Phosphatidylinositol signaling system 0.0324563 1.426
1992 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H003628_01 Info Dystroglycan 1 (dystrophin-associated glycoprotein 1) H003628_01 L19711 76111 DAG1 Agrin in Postsynaptic Differentiation, immunology 0.034627 0.774
1993 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H016134_01 Info V-akt murine thymoma viral oncogene homolog 2 H016134_01 NM_001626 326445 AKT2 Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction, tsonc 0.0530988 1.287
1994 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H001591_01 Info Phospholipase C, gamma 2 (phosphatidylinositol-specific) H001591_01 M37238 75648 PLCG2 Inositol phosphate metabolism, Phosphatidylinositol signaling system, cell_signaling, signal_transduction 0.1077771 1.239
1995 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H001748_01 Info Inositol 1,4,5-trisphosphate 3-kinase B H001748_01 X57206 78877 ITPKB Inositol phosphate metabolism, Phosphatidylinositol signaling system, cell_signaling, signal_transduction 0.1283627 0.851
1996 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H001718_01 Info Inositol 1,4,5-trisphosphate 3-kinase A H001718_01 X54938 2722 ITPKA Inositol phosphate metabolism, Phosphatidylinositol signaling system 0.1331494 1.16
1997 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H003550_01 Info Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) H003550_01 S76638 73090 NFKB2 gene_regulation, immunology, transcription, tsonc 0.1593331 1.165
1998 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H003747_01 Info Serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 H003747_01 L19684 159628 SERPINA4 0.2081201 0.866
1999 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H003870_01 Info Bruton agammaglobulinemia tyrosine kinase H003870_01 NM_000061 159494 BTK BCR Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Phosphoinositides and their downstream targets., cell_cycle, cell_signaling, immunology, signal_transduction 0.251649 1.148
2000 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H003441_01 Info Breakpoint cluster region H003441_01 X02596 234799 BCR Inhibition of Cellular Proliferation by Gleevec, Integrin Signaling Pathway, immunology, tsonc 0.2521813 1.116
2001 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H002405_01 Info Mitogen-activated protein kinase kinase 2 H002405_01 L11285 72241 MAP2K2 Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Bioactive Peptide Induced Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, fMLP induced chemokine gene expression in HMC-1 cells, Human Cytomegalovirus and Map Kinase Pathways, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Phosphorylation of MEK1 by cdk5/p35 down regulates the MAP kinase pathway, Role of MAL in Rho-Mediated Activation of SRF, Role of �-arrestins in the activation and targeting of MAP kinases, Roles of �-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling, Signaling of Hepatocyte Growth Factor Receptor 0.3118803 1.093
2002 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H003497_01 Info V-akt murine thymoma viral oncogene homolog 2 H003497_01 M77198 326445 AKT2 Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction, tsonc 0.3314111 0.872
2003 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H008413_01 Info Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 H008413_01 X77909 2764 NFKBIL1 0.5281661 1.058
2004 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H003612_01 Info V-akt murine thymoma viral oncogene homolog 1 H003612_01 M63167 71816 AKT1 Actions of Nitric Oxide in the Heart, AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, B Cell Survival Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia and p53 in the Cardiovascular system, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, mTOR Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Phospholipase C Signaling Pathway, Phospholipids as signaling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Ras Signaling Pathway, Regulation … 0.6741257 1.038
2005 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H001974_01 Info BCL2-antagonist of cell death H001974_01 U66879 76366 BAD AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, Ceramide Signaling Pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Phosphoinositides and their downstream targets., Ras Signaling Pathway, Regulation of BAD phosphorylation, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Trefoil Factors Initiate Mucosal Healing, apoptosis, development 0.6985187 0.954
2006 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H002722_01 Info Mitogen-activated protein kinase kinase 1 H002722_01 L11284 3446 MAP2K1 Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … 0.7377933 0.973
2007 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H003651_01 Info EphB2 H003651_01 AF025304 125124 EPHB2 development 0.7855294 0.971
2008 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H002447_01 Info Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha H002447_01 M69043 81328 NFKBIA Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Signal transduction through IL1R, T Cell Receptor Signaling Pathway, The 4-1BB-dependent immune … 0.8245205 0.975
2009 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H012662_01 Info Homo sapiens cDNA FLJ10205 fis, clone HEMBA1004954 H012662_01 AK001067 6226 0.8484663 1.017
2010 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H003711_01 Info Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) H003711_01 M58603 83428 NFKB1 Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Bone Remodelling, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Ceramide Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Corticosteroids and cardioprotection, CXCR4 Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, Free Radical Induced Apoptosis, HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of a … 0.8665095 1.017
2011 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H003340_01 Info C-src tyrosine kinase H003340_01 X60114 77793 CSK Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, Activation of Src by Protein-tyrosine phosphatase alpha, Cell to Cell Adhesion Signaling, Integrin Signaling Pathway, signal_transduction 0.9390319 1.008
2012 tidPathway_h BioCarta H003112_01 Info Retinoblastoma 1 (including osteosarcoma) H003112_01 L41870 75770 RB1 BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Chaperones modulate interferon Signaling Pathway, Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase RNA component gene hTerc Transcriptional Regulation, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Regulation of transcriptional activity by PML, Telomeres, Telomerase, Cellular Aging, and Immortality, TNFR1 Signaling Pathway, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, immunology, tsonc 0.0008596 0.674
2013 tidPathway_h BioCarta H002834_01 Info Interferon gamma receptor 2 (interferon gamma transducer 1) H002834_01 U05875 177559 IFNGR2 Chaperones modulate interferon Signaling Pathway, IFN gamma signaling pathway , Selective expression of chemokine receptors during T-cell polarization, Th1/Th2 Differentiation, immunology 0.0062495 1.401
2014 tidPathway_h BioCarta H002789_01 Info Tumor protein p53 (Li-Fraumeni syndrome) H002789_01 NM_000546 1846 TP53 Apoptotic Signaling in Response to DNA Damage, ATM Signaling Pathway, BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Chaperones modulate interferon Signaling Pathway, CTCF: First Multivalent Nuclear Factor, Double Stranded RNA Induced Gene Expression, Estrogen-responsive protein Efp controls cell cycle and breast tumors growth, Hypoxia and p53 in the Cardiovascular system, Overview of telomerase protein component gene hTert Transcriptional Regulation , p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of cell cycle progression by Plk3, Regulation of transcriptional activity by PML, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, DNA_damage, gene_regulation, immunology, transcription, tsonc 0.0273242 1.207
2015 tidPathway_h BioCarta H002506_01 Info Tumor necrosis factor receptor superfamily, member 1B H002506_01 M32315 256278 TNFRSF1B TNFR2 Signaling Pathway, immunology 0.1166754 1.17
2016 tidPathway_h BioCarta H006206_01 Info PDZ-73 protein H006206_01 AB006955 132945 PDZ-73/NY-CO-38 0.3146985 1.083
2017 tidPathway_h BioCarta H002447_01 Info Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha H002447_01 M69043 81328 NFKBIA Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Signal transduction through IL1R, T Cell Receptor Signaling Pathway, The 4-1BB-dependent immune … 0.8245205 0.975
2018 tidPathway_h BioCarta H012648_01 Info DnaJ (Hsp40) homolog, subfamily A, member 3 H012648_01 AF061749 311057 DNAJA3 Chaperones modulate interferon Signaling Pathway 0.8393634 0.984
2019 tidPathway_h BioCarta H003711_01 Info Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) H003711_01 M58603 83428 NFKB1 Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Bone Remodelling, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Ceramide Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Corticosteroids and cardioprotection, CXCR4 Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, Free Radical Induced Apoptosis, HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of a … 0.8665095 1.017
2020 tidPathway_h BioCarta H002963_01 Info V-rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide H002963_01 L19067 75569 RELA Acetylation and Deacetylation of RelA in The Nucleus, Erythropoietin mediated neuroprotection through NF-kB, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, immunology, tsonc 0.9724165 1.003
2021 DOWNREG_BY_HOXA9_h Manually Curated H003124_01 Info Fc fragment of IgG, receptor, transporter, alpha H003124_01 U12255 111903 FCGRT 2.86e-05 1.917
2022 DOWNREG_BY_HOXA9_h Manually Curated H002406_01 Info Jun B proto-oncogene H002406_01 X51345 198951 JUNB GATA3 participate in activating the Th2 cytokine genes expression, tsonc 0.0021761 1.408
2023 DOWNREG_BY_HOXA9_h Manually Curated H002878_01 Info V-yes-1 Yamaguchi sarcoma viral related oncogene homolog H002878_01 M16038 80887 LYN BCR Signaling Pathway, Eph Kinases and ephrins support platelet aggregation, Fc Epsilon Receptor I Signaling in Mast Cells, Phosphoinositides and their downstream targets., immunology, signal_transduction, tsonc 0.0068841 1.545
2024 DOWNREG_BY_HOXA9_h Manually Curated H000316_01 Info Delta sleep inducing peptide, immunoreactor H000316_01 AL110191 75450 DSIPI 0.0102545 1.531
2025 DOWNREG_BY_HOXA9_h Manually Curated H006355_01 Info KIAA1451 protein H006355_01 AL049923 109694 KIAA1451 0.0105169 1.369
2026 DOWNREG_BY_HOXA9_h Manually Curated H000199_01 Info Translocated promoter region (to activated MET oncogene) H000199_01 X66397 169750 TPR tsonc 0.036441 0.801
2027 DOWNREG_BY_HOXA9_h Manually Curated H001971_01 Info Retinoblastoma-binding protein 6 H001971_01 X85133 85273 RBBP6 0.0366619 0.747
2028 DOWNREG_BY_HOXA9_h Manually Curated H006255_01 Info Syndecan binding protein (syntenin) H006255_01 AF000652 8180 SDCBP 0.0567867 1.234
2029 DOWNREG_BY_HOXA9_h Manually Curated H002168_01 Info GATA-binding protein 2 H002168_01 M68891 760 GATA2 gene_regulation, misc, transcription 0.0841754 0.806
2030 DOWNREG_BY_HOXA9_h Manually Curated H004936_01 Info DKFZP564A122 protein H004936_01 AL110269 187991 DKFZP564A122 0.0852946 1.175
2031 DOWNREG_BY_HOXA9_h Manually Curated H007504_01 Info Hemoglobin, epsilon 1 H007504_01 NM_005330 117848 HBE1 0.118007 0.749
2032 DOWNREG_BY_HOXA9_h Manually Curated H002091_01 Info V-myc avian myelocytomatosis viral oncogene homolog H002091_01 K02276 79070 MYC Cadmium induces DNA synthesis and proliferation in macrophages, CTCF: First Multivalent Nuclear Factor, Erk1/Erk2 Mapk Signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, MAP Kinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, Overview of telomerase protein component gene hTert Transcriptional Regulation , p38 MAPK Signaling Pathway , Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, WNT Signaling Pathway, gene_regulation, immunology, transcription, tsonc 0.1797519 0.824
2033 DOWNREG_BY_HOXA9_h Manually Curated H001023_01 Info Mannosidase, alpha, class 2A, member 2 H001023_01 L28821 295605 MAN2A2 ER associated degradation (ERAD) Pathway, Steps in the Glycosylation of Mammalian N-linked Oligosaccharides, N-Glycan biosynthesis 0.2111813 1.139
2034 DOWNREG_BY_HOXA9_h Manually Curated H003255_01 Info CDC37 (cell division cycle 37, S. cerevisiae, homolog) H003255_01 U43077 160958 CDC37 0.2178008 0.878
2035 DOWNREG_BY_HOXA9_h Manually Curated H000068_01 Info Signal recognition particle 72kD H000068_01 AF069765 237825 SRP72 Perou’s – Intrinsic – Breast-Cancer-Genes 0.2609516 0.897
2036 DOWNREG_BY_HOXA9_h Manually Curated H012741_01 Info Glutaredoxin (thioltransferase) H012741_01 AF069668 28988 GLRX pharmacology 0.2704585 1.145
2037 DOWNREG_BY_HOXA9_h Manually Curated H006807_01 Info Cytokine inducible SH2-containing protein H006807_01 AF132297 8257 CISH Growth Hormone Signaling Pathway, IL-2 Receptor Beta Chain in T cell Activation, immunology 0.3746206 0.888
2038 DOWNREG_BY_HOXA9_h Manually Curated H006584_01 Info Splicing factor, arginine/serine-rich 11 H006584_01 M74002 11482 SFRS11 0.4576641 1.062
2039 DOWNREG_BY_HOXA9_h Manually Curated H016588_01 Info Hypothetical protein DKFZp761B2423 H016588_01 AK026954 91065 DKFZp761B2423 0.6339659 1.046
2040 DOWNREG_BY_HOXA9_h Manually Curated H010792_01 Info Dynein, cytoplasmic, light intermediate polypeptide 2 H010792_01 AF035812 194625 DNCLI2 0.6511108 1.058
2041 DOWNREG_BY_HOXA9_h Manually Curated H002850_01 Info Murine leukemia viral (bmi-1) oncogene homolog H002850_01 L13689 431 BMI1 Perou’s – Intrinsic – Breast-Cancer-Genes, The PRC2 Complex Sets Long-term Gene Silencing Through Modification of Histone Tails, immunology, tsonc 0.7846354 0.976
2042 DOWNREG_BY_HOXA9_h Manually Curated H003618_01 Info Dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2) H003618_01 D17547 301865 DCT Tyrosine metabolism 0.9648525 0.996
2043 ST_GRANULE_CELL_SURVIVAL_PATHWAY_h Signalling Transduction KE H006300_01 Info Hypothetical protein FLJ23239 H006300_01 AL137600 34516 FLJ23239 Glycosphingolipid metabolism 0.0007944 0.727
2044 ST_GRANULE_CELL_SURVIVAL_PATHWAY_h Signalling Transduction KE H008949_01 Info Hypothetical protein H008949_01 AF151024 122492 LOC51237 0.0022423 1.318
2045 ST_GRANULE_CELL_SURVIVAL_PATHWAY_h Signalling Transduction KE H000309_01 Info CAMP response element-binding protein CRE-BPa H000309_01 L05515 149 H_GS165L15.1 0.0078273 1.479
2046 ST_GRANULE_CELL_SURVIVAL_PATHWAY_h Signalling Transduction KE H003611_01 Info Mitogen-activated protein kinase kinase 4 H003611_01 L36870 75217 MAP2K4 Perou’s – Intrinsic – Breast-Cancer-Genes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Ceramide Signaling Pathway, EGF Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, Inhibition of Cellular Proliferation by Gleevec, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , PDGF Signaling Pathway, T Cell Receptor Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system 0.012502 0.753
2047 ST_GRANULE_CELL_SURVIVAL_PATHWAY_h Signalling Transduction KE H001062_01 Info N-acylsphingosine amidohydrolase (acid ceramidase) H001062_01 U70063 75811 ASAH Perou’s – Intrinsic – Breast-Cancer-Genes, Activation of cAMP-dependent protein kinase, PKA, Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, ChREBP regulation by carbohydrates and cAMP, Cystic fibrosis transmembrane conductance regulator (CFTR) and beta 2 adrenergic receptor (b2AR) pathway, How Progesterone Initiates the Oocyte Maturation, Ion Channels and Their Functional Role in Vascular Endothelium, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Phospholipase C-epsilon pathway, Phospholipids as signaling intermediaries, Regulation of BAD phosphorylation, Regulation of Spermatogenesis by CREM, Role of �-arrestins in the activation and targeting of MAP kinases, Roles of �-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling, Signaling Pathway from G-Protein Families, �-arrestins in GPCR Desensitization, Thrombin signaling and protease-activated receptors, Transcription factor CREB and its … 0.0187984 1.357
2048 ST_GRANULE_CELL_SURVIVAL_PATHWAY_h Signalling Transduction KE H003130_01 Info Interleukin 8 receptor, beta H003130_01 L19593 846 IL8RB immunology 0.0345675 1.307
2049 ST_GRANULE_CELL_SURVIVAL_PATHWAY_h Signalling Transduction KE H003628_01 Info Dystroglycan 1 (dystrophin-associated glycoprotein 1) H003628_01 L19711 76111 DAG1 Agrin in Postsynaptic Differentiation, immunology 0.034627 0.774
2050 ST_GRANULE_CELL_SURVIVAL_PATHWAY_h Signalling Transduction KE H001748_01 Info Inositol 1,4,5-trisphosphate 3-kinase B H001748_01 X57206 78877 ITPKB Inositol phosphate metabolism, Phosphatidylinositol signaling system, cell_signaling, signal_transduction 0.1283627 0.851
2051 ST_GRANULE_CELL_SURVIVAL_PATHWAY_h Signalling Transduction KE H003158_01 Info Mitogen-activated protein kinase 8 H003158_01 L26318 190913 MAPK8 Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig … 0.1287835 1.166
2052 ST_GRANULE_CELL_SURVIVAL_PATHWAY_h Signalling Transduction KE H001718_01 Info Inositol 1,4,5-trisphosphate 3-kinase A H001718_01 X54938 2722 ITPKA Inositol phosphate metabolism, Phosphatidylinositol signaling system 0.1331494 1.16
2053 ST_GRANULE_CELL_SURVIVAL_PATHWAY_h Signalling Transduction KE H003878_01 Info Caspase 3, apoptosis-related cysteine protease H003878_01 U13737 74552 CASP3 Apoptotic DNA fragmentation and tissue homeostasis, Apoptotic Signaling in Response to DNA Damage, B Cell Survival Pathway, Caspase Cascade in Apoptosis, D4-GDI Signaling Pathway, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Role of Mitochondria in Apoptotic Signaling, Stress Induction of HSP Regulation, TNFR1 Signaling Pathway, TSP-1 Induced Apoptosis in Microvascular Endothelial Cell , apoptosis, immunology 0.1364651 1.175
2054 ST_GRANULE_CELL_SURVIVAL_PATHWAY_h Signalling Transduction KE H003309_01 Info Mitogen-activated protein kinase kinase 7 H003309_01 AF013589 110299 MAP2K7 Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Keratinocyte Differentiation, MAP Kinase Signaling Pathway 0.3044184 1.088
2055 ST_GRANULE_CELL_SURVIVAL_PATHWAY_h Signalling Transduction KE H012904_01 Info Mitogen-activated protein kinase 8 interacting protein 3 H012904_01 AB028989 88500 MAPK8IP3 0.3112914 1.095
2056 ST_GRANULE_CELL_SURVIVAL_PATHWAY_h Signalling Transduction KE H011336_01 Info Guanine nucleotide binding protein (G protein), q polypeptide H011336_01 U43083 296261 GNAQ Activation of PKC through G protein coupled receptor, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, CCR3 signaling in Eosinophils, CXCR4 Signaling Pathway, Effects of calcineurin in Keratinocyte Differentiation, G-Protein Signaling Through Tubby Proteins, Links between Pyk2 and Map Kinases, Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, Pertussis toxin-insensitive CCR5 Signaling in Macrophage, PKC-catalyzed phosphorylation of inhibitory phosphoprotein of myosin phosphatase, Signaling Pathway from G-Protein Families, Thrombin signaling and protease-activated receptors, immunology 0.3713616 0.89
2057 ST_GRANULE_CELL_SURVIVAL_PATHWAY_h Signalling Transduction KE H014634_01 Info Homo sapiens mRNA for FLJ00027 protein, partial CDS H014634_01 AK024437 199417 0.6135149 1.048
2058 ST_GRANULE_CELL_SURVIVAL_PATHWAY_h Signalling Transduction KE H006635_01 Info Homo sapiens clone 23607 mRNA sequence H006635_01 AF038181 167825 ALK in cardiac myocytes, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Multi-step Regulation of Transcription by Pitx2, Presenilin action in Notch and Wnt signaling, TGF beta signaling pathway, WNT Signaling Pathway, development, immunology, tsonc 0.6181322 1.041
2059 ST_GRANULE_CELL_SURVIVAL_PATHWAY_h Signalling Transduction KE H003651_01 Info EphB2 H003651_01 AF025304 125124 EPHB2 development 0.7855294 0.971
2060 ST_GRANULE_CELL_SURVIVAL_PATHWAY_h Signalling Transduction KE H003163_01 Info CAMP responsive element binding protein 1 H003163_01 M27691 79194 CREB1 Ca++/ Calmodulin-dependent Protein Kinase Activation, Calcium Signaling by HBx of Hepatitis B virus, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia-Inducible Factor in the Cardiovascular System, Inhibition of Huntington\’s disease neurodegeneration by histone deacetylase inhibitors, MAP Kinase Signaling Pathway, Melanocyte Development and Pigmentation Pathway, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Repression of Pain Sensation by the Transcriptional Regulator DREAM, Role of Erk5 in Neuronal Survival, Signaling Pathway from G-Protein Families, Transcription factor CREB and its extracellular signals, Transcription Regulation by Methyltransferase of CARM1, immunology 0.9300928 1.009
2061 ST_GRANULE_CELL_SURVIVAL_PATHWAY_h Signalling Transduction KE H014820_01 Info Mitogen-activated protein kinase 9 H014820_01 NM_002752 246857 MAPK9 MAP Kinase Signaling Pathway, Phosphatidylinositol signaling system 0.9883614 0.998
2062 bcrPathway_h B cell antigen receptors (BCRs) activate tyrosine kinases and transiently increase tyrosine phosphorylation on binding to antigen. H002055_01 Info Growth factor receptor-bound protein 2 H002055_01 M96995 296381 GRB2 Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel … 0.0022348 1.459
2063 bcrPathway_h B cell antigen receptors (BCRs) activate tyrosine kinases and transiently increase tyrosine phosphorylation on binding to antigen. H002893_01 Info V-raf-1 murine leukemia viral oncogene homolog 1 H002893_01 X03484 85181 RAF1 Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … 0.0062484 1.596
2064 bcrPathway_h B cell antigen receptors (BCRs) activate tyrosine kinases and transiently increase tyrosine phosphorylation on binding to antigen. H002878_01 Info V-yes-1 Yamaguchi sarcoma viral related oncogene homolog H002878_01 M16038 80887 LYN BCR Signaling Pathway, Eph Kinases and ephrins support platelet aggregation, Fc Epsilon Receptor I Signaling in Mast Cells, Phosphoinositides and their downstream targets., immunology, signal_transduction, tsonc 0.0068841 1.545
2065 bcrPathway_h B cell antigen receptors (BCRs) activate tyrosine kinases and transiently increase tyrosine phosphorylation on binding to antigen. H002895_01 Info Mitogen-activated protein kinase 14 H002895_01 L35263 79107 MAPK14 BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAP Kinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm … 0.0086925 1.429
2066 bcrPathway_h B cell antigen receptors (BCRs) activate tyrosine kinases and transiently increase tyrosine phosphorylation on binding to antigen. H001365_01 Info Protein kinase C, beta 1 H001365_01 X07109 77202 PRKCB1 Bioactive Peptide Induced Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Ion Channel and Phorbol Esters Signaling Pathway, T Cell Receptor Signaling Pathway, Phosphatidylinositol signaling system, angiogenesis, cell_cycle, cell_signaling, signal_transduction 0.0304335 1.379
2067 bcrPathway_h B cell antigen receptors (BCRs) activate tyrosine kinases and transiently increase tyrosine phosphorylation on binding to antigen. H003178_01 Info Mitogen-activated protein kinase 3 H003178_01 X60188 861 MAPK3 Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … 0.0986041 1.184
2068 bcrPathway_h B cell antigen receptors (BCRs) activate tyrosine kinases and transiently increase tyrosine phosphorylation on binding to antigen. H003158_01 Info Mitogen-activated protein kinase 8 H003158_01 L26318 190913 MAPK8 Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig … 0.1287835 1.166
2069 bcrPathway_h B cell antigen receptors (BCRs) activate tyrosine kinases and transiently increase tyrosine phosphorylation on binding to antigen. H002501_01 Info Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) H002501_01 D25274 173737 RAC1 Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, fMLP induced chemokine gene expression in HMC-1 cells, How does salmonella hijack a cell, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , Phosphoinositides and their downstream targets., Phospholipids as signaling intermediaries, Rac 1 cell motility signaling pathway, Ras Signaling Pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of MAL in Rho-Mediated Activation of SRF, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, T Cell Receptor Signaling Pathway, Transcription factor CREB and its extracellular signals, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, uCalpain and friends in Cell spread, Y branching of actin filaments 0.1980127 1.118
2070 bcrPathway_h B cell antigen receptors (BCRs) activate tyrosine kinases and transiently increase tyrosine phosphorylation on binding to antigen. H003870_01 Info Bruton agammaglobulinemia tyrosine kinase H003870_01 NM_000061 159494 BTK BCR Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Phosphoinositides and their downstream targets., cell_cycle, cell_signaling, immunology, signal_transduction 0.251649 1.148
2071 bcrPathway_h B cell antigen receptors (BCRs) activate tyrosine kinases and transiently increase tyrosine phosphorylation on binding to antigen. H001979_01 Info Protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform (calcineurin A beta) H001979_01 M29551 151531 PPP3CB cell_cycle, cell_signaling 0.3386238 0.898
2072 bcrPathway_h B cell antigen receptors (BCRs) activate tyrosine kinases and transiently increase tyrosine phosphorylation on binding to antigen. H003578_01 Info Protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform (calcineurin A gamma) H003578_01 S46622 75206 PPP3CC 0.5197011 0.934
2073 bcrPathway_h B cell antigen receptors (BCRs) activate tyrosine kinases and transiently increase tyrosine phosphorylation on binding to antigen. H002045_01 Info Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 H002045_01 U80917 96149 NFATC1 BCR Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Effects of calcineurin in Keratinocyte Differentiation, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Role of MEF2D in T-cell Apoptosis, Signaling Pathway from G-Protein Families, T Cell Receptor Signaling Pathway, immunology 0.623508 1.051
2074 bcrPathway_h B cell antigen receptors (BCRs) activate tyrosine kinases and transiently increase tyrosine phosphorylation on binding to antigen. H002470_01 Info Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 H002470_01 L41067 172674 NFATC3 immunology 0.7190859 0.97
2075 bcrPathway_h B cell antigen receptors (BCRs) activate tyrosine kinases and transiently increase tyrosine phosphorylation on binding to antigen. H002722_01 Info Mitogen-activated protein kinase kinase 1 H002722_01 L11284 3446 MAP2K1 Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … 0.7377933 0.973
2076 bcrPathway_h B cell antigen receptors (BCRs) activate tyrosine kinases and transiently increase tyrosine phosphorylation on binding to antigen. H003499_01 Info CD79B antigen (immunoglobulin-associated beta) H003499_01 M89957 89575 CD79B B Cell Receptor Complex, BCR Signaling Pathway, CTCF: First Multivalent Nuclear Factor, immunology 0.8100034 1.033
2077 bcrPathway_h B cell antigen receptors (BCRs) activate tyrosine kinases and transiently increase tyrosine phosphorylation on binding to antigen. H002404_01 Info Synaptotagmin I H002404_01 M55047 154679 SYT1 0.8170962 0.971
2078 bcrPathway_h B cell antigen receptors (BCRs) activate tyrosine kinases and transiently increase tyrosine phosphorylation on binding to antigen. H000579_01 Info Calmodulin 2 (phosphorylase kinase, delta) H000579_01 D45887 182278 CALM2 0.9689776 1.004
2079 egfr_smrtePathway_h EGF receptor activation inhibits SMRT, a transcriptional co-repressor that interacts with transcription factor complexes and gene silencers. H002040_01 Info Epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog) H002040_01 X00588 77432 EGFR Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Keratinocyte Differentiation, Map Kinase Inactivation of SMRT Corepressor, mCalpain and friends in Cell motility, Neuroregulin receptor degradation protein-1 Controls ErbB3 receptor recycling, Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Role of ERBB2 in Signal Transduction and Oncology, Sprouty regulation of tyrosine kinase signals, Telomeres, Telomerase, Cellular Aging, and Immortality, The role of FYVE-finger proteins in vesicle transport, Trefoil Factors Initiate Mucosal Healing, angiogenesis, signal_transduction, tsonc 0.0004362 0.669
2080 egfr_smrtePathway_h EGF receptor activation inhibits SMRT, a transcriptional co-repressor that interacts with transcription factor complexes and gene silencers. H002895_01 Info Mitogen-activated protein kinase 14 H002895_01 L35263 79107 MAPK14 BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAP Kinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm … 0.0086925 1.429
2081 egfr_smrtePathway_h EGF receptor activation inhibits SMRT, a transcriptional co-repressor that interacts with transcription factor complexes and gene silencers. H003606_01 Info Retinoid X receptor, alpha H003606_01 U66306 20084 RXRA Basic mechanism of action of PPARa, PPARb(d) and PPARg and effects on gene expression, Control of Gene Expression by Vitamin D Receptor, Degradation of the RAR and RXR by the proteasome, FXR and LXR Regulation of Cholesterol Metabolism, Map Kinase Inactivation of SMRT Corepressor, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells, Role of PPAR-gamma Coactivators in Obesity and Thermogenesis, Transcription Regulation by Methyltransferase of CARM1, Visceral Fat Deposits and the Metabolic Syndrome, development, gene_regulation, transcription 0.0142664 1.308
2082 egfr_smrtePathway_h EGF receptor activation inhibits SMRT, a transcriptional co-repressor that interacts with transcription factor complexes and gene silencers. H002882_01 Info Nuclear receptor co-repressor 2 H002882_01 NM_006312 287994 NCOR2 CARM1 and Regulation of the Estrogen Receptor, Map Kinase Inactivation of SMRT Corepressor, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), METS affect on Macrophage Differentiation, Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells 0.3492591 0.931
2083 egfr_smrtePathway_h EGF receptor activation inhibits SMRT, a transcriptional co-repressor that interacts with transcription factor complexes and gene silencers. H002907_01 Info Retinoic acid receptor, alpha H002907_01 X06614 250505 RARA Degradation of the RAR and RXR by the proteasome, Map Kinase Inactivation of SMRT Corepressor, Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells, Nuclear Receptors in Lipid Metabolism and Toxicity, Regulation of transcriptional activity by PML, Transcription Regulation by Methyltransferase of CARM1, development 0.4825926 1.084
2084 egfr_smrtePathway_h EGF receptor activation inhibits SMRT, a transcriptional co-repressor that interacts with transcription factor complexes and gene silencers. H002722_01 Info Mitogen-activated protein kinase kinase 1 H002722_01 L11284 3446 MAP2K1 Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … 0.7377933 0.973
2085 HEMO_TF_LIST_JP_h Manually Curated H003463_01 Info Spleen focus forming virus (SFFV) proviral integration oncogene spi1 H003463_01 X52056 157441 SPI1 tsonc 0.0010958 1.855
2086 HEMO_TF_LIST_JP_h Manually Curated H002186_01 Info Serum response factor (c-fos serum response element-binding transcription factor) H002186_01 J03161 155321 SRF EGF Signaling Pathway, Growth Hormone Signaling Pathway, Hop Pathway in Cardiac Development, IGF-1 Signaling Pathway, IL 6 signaling pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, cell_cycle, cell_signaling, development, gene_regulation, transcription 0.0017465 0.722
2087 HEMO_TF_LIST_JP_h Manually Curated H001284_01 Info Myeloid/lymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog) H001284_01 L04731 199160 MLL misc 0.0019854 0.707
2088 HEMO_TF_LIST_JP_h Manually Curated H003948_01 Info Nuclear factor (erythroid-derived 2), 45kD H003948_01 S77763 75643 NFE2 gene_regulation, immunology, transcription 0.0024537 1.435
2089 HEMO_TF_LIST_JP_h Manually Curated H000570_01 Info CREB binding protein (Rubinstein-Taybi syndrome) H000570_01 U47741 23598 CREBBP gene_regulation, transcription 0.0048718 1.469
2090 HEMO_TF_LIST_JP_h Manually Curated H000640_01 Info Ets variant gene 4 (E1A enhancer-binding protein, E1AF) H000640_01 U18018 77711 ETV4 gene_regulation, immunology, transcription 0.0049082 0.628
2091 HEMO_TF_LIST_JP_h Manually Curated H013956_01 Info Kruppel-like factor 1 (erythroid) H013956_01 U65404 37860 KLF1 0.0114587 1.338
2092 HEMO_TF_LIST_JP_h Manually Curated H001315_01 Info Runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene) H001315_01 D43968 129914 RUNX1 0.0288879 0.822
2093 HEMO_TF_LIST_JP_h Manually Curated H007370_01 Info Kruppel-like factor 13 H007370_01 NM_015995 7104 KLF13 0.0315326 1.302
2094 HEMO_TF_LIST_JP_h Manually Curated H002057_01 Info Zinc finger protein 42 (myeloid-specific retinoic acid- responsive) H002057_01 AF055078 169832 ZNF42 gene_regulation, transcription 0.0372699 0.808
2095 HEMO_TF_LIST_JP_h Manually Curated H016113_01 Info Homeo box B8 H016113_01 NM_024016 324916 HOXB8 development 0.0540634 1.307
2096 HEMO_TF_LIST_JP_h Manually Curated H002315_01 Info Transcription factor AP-4 (activating enhancer-binding protein 4) H002315_01 S73885 3005 TFAP4 gene_regulation, transcription 0.0600253 0.853
2097 HEMO_TF_LIST_JP_h Manually Curated H000315_01 Info Nuclear factor I/C (CCAAT-binding transcription factor) H000315_01 X12492 184771 NFIC 0.07748 0.815
2098 HEMO_TF_LIST_JP_h Manually Curated H002168_01 Info GATA-binding protein 2 H002168_01 M68891 760 GATA2 gene_regulation, misc, transcription 0.0841754 0.806
2099 HEMO_TF_LIST_JP_h Manually Curated H000251_01 Info Mediterranean fever H000251_01 AF018080 173730 MEFV 0.0879179 1.152
2100 HEMO_TF_LIST_JP_h Manually Curated H008525_01 Info Homo sapiens cDNA FLJ12900 fis, clone NT2RP2004321 H008525_01 AL049381 21851 Perou’s – Intrinsic – Breast-Cancer-Genes, development, gene_regulation, transcription 0.0950204 0.767
2101 HEMO_TF_LIST_JP_h Manually Curated H001313_01 Info Hematopoietically expressed homeobox H001313_01 L16499 118651 HHEX misc, transcription 0.110793 1.2
2102 HEMO_TF_LIST_JP_h Manually Curated H003249_01 Info V-ets avian erythroblastosis virus E26 oncogene homolog 1 H003249_01 X14798 248109 ETS1 Keratinocyte Differentiation, METS affect on Macrophage Differentiation, tsonc 0.1428371 0.878
2103 HEMO_TF_LIST_JP_h Manually Curated H003550_01 Info Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) H003550_01 S76638 73090 NFKB2 gene_regulation, immunology, transcription, tsonc 0.1593331 1.165
2104 HEMO_TF_LIST_JP_h Manually Curated H001297_01 Info Pre-B-cell leukemia transcription factor 1 H001297_01 M86546 155691 PBX1 Perou’s – Intrinsic – Breast-Cancer-Genes, development, gene_regulation, transcription 0.1724831 1.132
2105 HEMO_TF_LIST_JP_h Manually Curated H002091_01 Info V-myc avian myelocytomatosis viral oncogene homolog H002091_01 K02276 79070 MYC Cadmium induces DNA synthesis and proliferation in macrophages, CTCF: First Multivalent Nuclear Factor, Erk1/Erk2 Mapk Signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, MAP Kinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, Overview of telomerase protein component gene hTert Transcriptional Regulation , p38 MAPK Signaling Pathway , Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, WNT Signaling Pathway, gene_regulation, immunology, transcription, tsonc 0.1797519 0.824
2106 HEMO_TF_LIST_JP_h Manually Curated H013484_01 Info H2.0 (Drosophila)-like homeo box 1 H013484_01 M60721 74870 HLX1 immunology 0.1970503 1.197
2107 HEMO_TF_LIST_JP_h Manually Curated H003787_01 Info LIM domain only 2 (rhombotin-like 1) H003787_01 X61118 184585 LMO2 0.2060088 1.164
2108 HEMO_TF_LIST_JP_h Manually Curated H015892_01 Info Early development regulator 1 (homolog of polyhomeotic 1) H015892_01 NM_004426 305985 EDR1 The PRC2 Complex Sets Long-term Gene Silencing Through Modification of Histone Tails 0.2199906 0.855
2109 HEMO_TF_LIST_JP_h Manually Curated H003656_01 Info Ets variant gene 6 (TEL oncogene) H003656_01 U11732 169081 ETV6 immunology, tsonc 0.3132143 0.905
2110 HEMO_TF_LIST_JP_h Manually Curated H002611_01 Info Interferon regulatory factor 1 H002611_01 X14454 80645 IRF1 gene_regulation, transcription 0.3284273 0.915
2111 HEMO_TF_LIST_JP_h Manually Curated H012191_01 Info Meis1 (mouse) homolog H012191_01 U85707 170177 MEIS1 development 0.3687496 1.11
2112 HEMO_TF_LIST_JP_h Manually Curated H002241_01 Info POU domain, class 2, transcription factor 1 H002241_01 X13403 182237 POU2F1 gene_regulation, misc, transcription 0.4573205 1.072
2113 HEMO_TF_LIST_JP_h Manually Curated H003580_01 Info Nuclear factor I/X (CCAAT-binding transcription factor) H003580_01 L31881 35841 NFIX 0.4626847 0.927
2114 HEMO_TF_LIST_JP_h Manually Curated H011704_01 Info GATA-binding protein 1 (globin transcription factor 1) H011704_01 X17254 765 GATA1 Hemoglobin\’s Chaperone, gene_regulation, misc, transcription 0.4642197 1.099
2115 HEMO_TF_LIST_JP_h Manually Curated H010176_01 Info Homeo box C4 H010176_01 X07495 50895 HOXC4 development 0.5228139 0.945
2116 HEMO_TF_LIST_JP_h Manually Curated H007160_01 Info E2F transcription factor 2 H007160_01 L22846 121487 E2F2 cell_cycle, gene_regulation, transcription 0.5789709 0.945
2117 HEMO_TF_LIST_JP_h Manually Curated H002518_01 Info Zinc finger protein, subfamily 1A, 1 (Ikaros) H002518_01 U40462 54452 ZNFN1A1 0.5915437 0.94
2118 HEMO_TF_LIST_JP_h Manually Curated H009346_01 Info AML1 H009346_01 S76346 166060 0.6048212 1.054
2119 HEMO_TF_LIST_JP_h Manually Curated H012261_01 Info Homeo box C6 H012261_01 M16938 820 HOXC6 development 0.6427939 0.963
2120 HEMO_TF_LIST_JP_h Manually Curated H002070_01 Info Transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) H002070_01 M31523 101047 TCF3 gene_regulation, immunology, transcription 0.6844305 0.958
2121 HEMO_TF_LIST_JP_h Manually Curated H014209_01 Info Homo sapiens NOTCH 1 (N1) mRNA, complete CDS H014209_01 AF308602 129053 Presenilin action in Notch and Wnt signaling, Proteolysis and Signaling Pathway of Notch , Segmentation Clock, immunology 0.7088381 1.031
2122 HEMO_TF_LIST_JP_h Manually Curated H007855_01 Info Kreisler (mouse) maf-related leucine zipper homolog H007855_01 NM_005461 169487 KRML 0.7205744 0.957
2123 HEMO_TF_LIST_JP_h Manually Curated H002850_01 Info Murine leukemia viral (bmi-1) oncogene homolog H002850_01 L13689 431 BMI1 Perou’s – Intrinsic – Breast-Cancer-Genes, The PRC2 Complex Sets Long-term Gene Silencing Through Modification of Histone Tails, immunology, tsonc 0.7846354 0.976
2124 HEMO_TF_LIST_JP_h Manually Curated H007065_01 Info Growth factor independent 1 H007065_01 U67369 73172 GFI1 immunology 0.8418068 0.979
2125 HEMO_TF_LIST_JP_h Manually Curated H003711_01 Info Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) H003711_01 M58603 83428 NFKB1 Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Bone Remodelling, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Ceramide Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Corticosteroids and cardioprotection, CXCR4 Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, Free Radical Induced Apoptosis, HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of a … 0.8665095 1.017
2126 HEMO_TF_LIST_JP_h Manually Curated H000647_01 Info E74-like factor 1 (ets domain transcription factor) H000647_01 M82882 154365 ELF1 gene_regulation, transcription 0.879249 1.014
2127 HEMO_TF_LIST_JP_h Manually Curated H003151_01 Info E1A binding protein p300 H003151_01 U01877 25272 EP300 Acetylation and Deacetylation of RelA in The Nucleus, CARM1 and Regulation of the Estrogen Receptor, Cell Cycle: G2/M Checkpoint, Control of Gene Expression by Vitamin D Receptor, Hypoxia and p53 in the Cardiovascular system, Hypoxia-Inducible Factor in the Cardiovascular System, IL-7 Signal Transduction, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Melanocyte Development and Pigmentation Pathway, Multi-step Regulation of Transcription by Pitx2, NFkB activation by Nontypeable Hemophilus influenzae, Pelp1 Modulation of Estrogen Receptor Activity, Role of ERBB2 in Signal Transduction and Oncology, Role of MEF2D in T-cell Apoptosis, Role of PPAR-gamma Coactivators in Obesity and Thermogenesis, TGF beta signaling pathway, Transcription Regulation by Methyltransferase of CARM1, gene_regulation, transcription 0.9607239 1.004
2128 HEMO_TF_LIST_JP_h Manually Curated H000247_01 Info Sp3 transcription factor H000247_01 X68560 44450 SP3 Effects of calcineurin in Keratinocyte Differentiation, Overview of telomerase protein component gene hTert Transcriptional Regulation , Overview of telomerase RNA component gene hTerc Transcriptional Regulation 0.985621 0.998
2129 HEMO_TF_LIST_JP_h Manually Curated H005603_01 Info High-mobility group (nonhistone chromosomal) protein 4 H005603_01 Y10043 19114 HMG4 0.9931402 1.001
2130 hcmvPathway_h BioCarta H003112_01 Info Retinoblastoma 1 (including osteosarcoma) H003112_01 L41870 75770 RB1 BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Chaperones modulate interferon Signaling Pathway, Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase RNA component gene hTerc Transcriptional Regulation, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Regulation of transcriptional activity by PML, Telomeres, Telomerase, Cellular Aging, and Immortality, TNFR1 Signaling Pathway, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, immunology, tsonc 0.0008596 0.674
2131 hcmvPathway_h BioCarta H003200_01 Info Mitogen-activated protein kinase kinase 3 H003200_01 D87116 180533 MAP2K3 fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Signal transduction through IL1R, TNF/Stress Related Signaling, Toll-Like Receptor Pathway 0.0009666 1.561
2132 hcmvPathway_h BioCarta H002895_01 Info Mitogen-activated protein kinase 14 H002895_01 L35263 79107 MAPK14 BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAP Kinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm … 0.0086925 1.429
2133 hcmvPathway_h BioCarta H003259_01 Info Sp1 transcription factor H003259_01 J03133 2021 SP1 Agrin in Postsynaptic Differentiation, Effects of calcineurin in Keratinocyte Differentiation, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase protein component gene hTert Transcriptional Regulation , Overview of telomerase RNA component gene hTerc Transcriptional Regulation 0.0557417 0.814
2134 hcmvPathway_h BioCarta H003178_01 Info Mitogen-activated protein kinase 3 H003178_01 X60188 861 MAPK3 Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … 0.0986041 1.184
2135 hcmvPathway_h BioCarta H002405_01 Info Mitogen-activated protein kinase kinase 2 H002405_01 L11285 72241 MAP2K2 Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Bioactive Peptide Induced Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, fMLP induced chemokine gene expression in HMC-1 cells, Human Cytomegalovirus and Map Kinase Pathways, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Phosphorylation of MEK1 by cdk5/p35 down regulates the MAP kinase pathway, Role of MAL in Rho-Mediated Activation of SRF, Role of �-arrestins in the activation and targeting of MAP kinases, Roles of �-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling, Signaling of Hepatocyte Growth Factor Receptor 0.3118803 1.093
2136 hcmvPathway_h BioCarta H003612_01 Info V-akt murine thymoma viral oncogene homolog 1 H003612_01 M63167 71816 AKT1 Actions of Nitric Oxide in the Heart, AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, B Cell Survival Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia and p53 in the Cardiovascular system, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, mTOR Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Phospholipase C Signaling Pathway, Phospholipids as signaling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Ras Signaling Pathway, Regulation … 0.6741257 1.038
2137 hcmvPathway_h BioCarta H002722_01 Info Mitogen-activated protein kinase kinase 1 H002722_01 L11284 3446 MAP2K1 Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … 0.7377933 0.973
2138 hcmvPathway_h BioCarta H003711_01 Info Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) H003711_01 M58603 83428 NFKB1 Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Bone Remodelling, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Ceramide Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Corticosteroids and cardioprotection, CXCR4 Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, Free Radical Induced Apoptosis, HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of a … 0.8665095 1.017
2139 hcmvPathway_h BioCarta H003163_01 Info CAMP responsive element binding protein 1 H003163_01 M27691 79194 CREB1 Ca++/ Calmodulin-dependent Protein Kinase Activation, Calcium Signaling by HBx of Hepatitis B virus, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia-Inducible Factor in the Cardiovascular System, Inhibition of Huntington\’s disease neurodegeneration by histone deacetylase inhibitors, MAP Kinase Signaling Pathway, Melanocyte Development and Pigmentation Pathway, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway, Repression of Pain Sensation by the Transcriptional Regulator DREAM, Role of Erk5 in Neuronal Survival, Signaling Pathway from G-Protein Families, Transcription factor CREB and its extracellular signals, Transcription Regulation by Methyltransferase of CARM1, immunology 0.9300928 1.009
2140 hcmvPathway_h BioCarta H002963_01 Info V-rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide H002963_01 L19067 75569 RELA Acetylation and Deacetylation of RelA in The Nucleus, Erythropoietin mediated neuroprotection through NF-kB, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, immunology, tsonc 0.9724165 1.003
2141 MAP00051_Fructose_and_mannose_metabolism_h GenMAPP H002486_01 Info Glucokinase (hexokinase 4, maturity onset diabetes of the young 2) H002486_01 M90299 1270 GCK Aminosugars metabolism, Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Starch and sucrose metabolism, Streptomycin biosynthesis, immunology 0.0014569 1.288
2142 MAP00051_Fructose_and_mannose_metabolism_h GenMAPP H004823_01 Info Aldolase C, fructose-bisphosphate H004823_01 AF054987 155247 ALDOC Carbon fixation, Fructose and mannose metabolism, Glycolysis / Gluconeogenesis, Inositol metabolism, Pentose phosphate pathway 0.001576 0.707
2143 MAP00051_Fructose_and_mannose_metabolism_h GenMAPP H004836_01 Info GDP-mannose pyrophosphorylase A H004836_01 AK000999 27059 GMPPA Fructose and mannose metabolism 0.00381 0.698
2144 MAP00051_Fructose_and_mannose_metabolism_h GenMAPP H003374_01 Info Aldolase A, fructose-bisphosphate H003374_01 M11560 273415 ALDOA Downregulated of MTA-3 in ER-negative Breast Tumors, Carbon fixation, Fructose and mannose metabolism, Glycolysis / Gluconeogenesis, Inositol metabolism, Pentose phosphate pathway, immunology 0.0300936 1.252
2145 MAP00051_Fructose_and_mannose_metabolism_h GenMAPP H001522_01 Info Aldo-keto reductase family 1, member B1 (aldose reductase) H001522_01 X15414 75313 AKR1B1 Fructose and mannose metabolism, Galactose metabolism, Glycerolipid metabolism, Pentose and glucuronate interconversions, Pyruvate metabolism 0.0453087 0.846
2146 MAP00051_Fructose_and_mannose_metabolism_h GenMAPP H001387_01 Info Phosphofructokinase, platelet H001387_01 D25328 99910 PFKP Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Pentose phosphate pathway, immunology 0.101431 0.866
2147 MAP00051_Fructose_and_mannose_metabolism_h GenMAPP H005470_01 Info Homo sapiens mRNA; cDNA DKFZp762B245 (from clone DKFZp762B245); partial CDS H005470_01 AL162062 198182 0.1944956 1.125
2148 MAP00051_Fructose_and_mannose_metabolism_h GenMAPP H011651_01 Info 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 H011651_01 X52638 739 PFKFB1 Fructose and mannose metabolism 0.2588895 1.131
2149 MAP00051_Fructose_and_mannose_metabolism_h GenMAPP H001378_01 Info Phosphofructokinase, muscle H001378_01 U24183 75160 PFKM Phosphoinositides and their downstream targets., Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Pentose phosphate pathway, immunology 0.2927445 0.908
2150 MAP00051_Fructose_and_mannose_metabolism_h GenMAPP H001535_01 Info Sorbitol dehydrogenase H001535_01 L29008 878 SORD Fructose and mannose metabolism, metabolism 0.3484797 1.082
2151 MAP00051_Fructose_and_mannose_metabolism_h GenMAPP H005772_01 Info Phosphomannomutase 2 H005772_01 U85773 154695 PMM2 Fructose and mannose metabolism 0.9121231 0.987
2152 MAP00051_Fructose_and_mannose_metabolism_h GenMAPP H001385_01 Info Phosphofructokinase, liver H001385_01 X15573 155455 PFKL Glycolysis Pathway, Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Pentose phosphate pathway, immunology 0.9581627 1.005
2153 MAP_kinase_kinase_activity_h GenMAPP H003200_01 Info Mitogen-activated protein kinase kinase 3 H003200_01 D87116 180533 MAP2K3 fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Signal transduction through IL1R, TNF/Stress Related Signaling, Toll-Like Receptor Pathway 0.0009666 1.561
2154 MAP_kinase_kinase_activity_h GenMAPP H002895_01 Info Mitogen-activated protein kinase 14 H002895_01 L35263 79107 MAPK14 BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAP Kinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm … 0.0086925 1.429
2155 MAP_kinase_kinase_activity_h GenMAPP H003309_01 Info Mitogen-activated protein kinase kinase 7 H003309_01 AF013589 110299 MAP2K7 Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Keratinocyte Differentiation, MAP Kinase Signaling Pathway 0.3044184 1.088
2156 MAP_kinase_kinase_activity_h GenMAPP H002722_01 Info Mitogen-activated protein kinase kinase 1 H002722_01 L11284 3446 MAP2K1 Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … 0.7377933 0.973
2157 MAP_kinase_kinase_activity_h GenMAPP H002580_01 Info Mitogen-activated protein kinase-activated protein kinase 3 H002580_01 U09578 227789 MAPKAPK3 MAP Kinase Signaling Pathway, Stress Induction of HSP Regulation, immunology 0.8269383 0.981
2158 LEU_UP_h Peng_et_al_2002 H001704_01 Info Protein phosphatase 2, regulatory subunit B (B56), gamma isoform H001704_01 U37352 171734 PPP2R5C signal_transduction 0.0003843 0.708
2159 LEU_UP_h Peng_et_al_2002 H000670_01 Info Interferon stimulated gene (20kD) H000670_01 U88964 183487 ISG20 cell_cycle, cell_signaling 0.0004988 1.6
2160 LEU_UP_h Peng_et_al_2002 H002552_01 Info Integrin beta 3 binding protein (beta3-endonexin) H002552_01 U37139 82084 ITGB3BP 0.0013566 0.728
2161 LEU_UP_h Peng_et_al_2002 H009875_01 Info Lysosomal-associated multispanning membrane protein-5 H009875_01 U51240 79356 LAPTM5 0.0035021 1.539
2162 LEU_UP_h Peng_et_al_2002 H002398_01 Info CD22 antigen H002398_01 X59350 171763 CD22 angiogenesis, immunology, metastasis 0.0039052 1.468
2163 LEU_UP_h Peng_et_al_2002 H003036_01 Info Bone morphogenetic protein 7 (osteogenic protein 1) H003036_01 X51801 170195 BMP7 ALK in cardiac myocytes, development 0.0073416 0.679
2164 LEU_UP_h Peng_et_al_2002 H011715_01 Info Plexin B2 H011715_01 AB002313 3989 PLXNB2 0.0128867 1.248
2165 LEU_UP_h Peng_et_al_2002 H009608_01 Info Absent in melanoma 1 H009608_01 U83115 161002 AIM1 0.0140873 1.306
2166 LEU_UP_h Peng_et_al_2002 H003493_01 Info MADS box transcription enhancer factor 2, polypeptide B (myocyte enhancer factor 2B) H003493_01 X63380 78881 MEF2B 0.0145042 1.328
2167 LEU_UP_h Peng_et_al_2002 H012762_01 Info POU transcription factor H012762_01 NM_014352 227115 11-Oct 0.0161056 1.229
2168 LEU_UP_h Peng_et_al_2002 H009473_01 Info DKFZP586D0623 protein H009473_01 AL050197 44468 DKFZP586D0623 0.034552 1.201
2169 LEU_UP_h Peng_et_al_2002 H002149_01 Info Cyclin-dependent kinase inhibitor 1A (p21, Cip1) H002149_01 U03106 179665 CDKN1A ATM Signaling Pathway, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, Effects of calcineurin in Keratinocyte Differentiation, Erythropoietin mediated neuroprotection through NF-kB, Hypoxia and p53 in the Cardiovascular system, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, immunology, tsonc 0.0349766 1.236
2170 LEU_UP_h Peng_et_al_2002 H008794_01 Info Prostate cancer overexpressed gene 1 H008794_01 AF045584 18910 POV1 0.0472666 0.794
2171 LEU_UP_h Peng_et_al_2002 H008614_01 Info Cold inducible RNA-binding protein H008614_01 D78134 119475 CIRBP 0.0552495 1.222
2172 LEU_UP_h Peng_et_al_2002 H009951_01 Info Exportin, tRNA (nuclear export receptor for tRNAs) H009951_01 AF039022 85951 XPOT 0.0554912 0.798
2173 LEU_UP_h Peng_et_al_2002 H000887_01 Info Prosaposin (variant Gaucher disease and variant metachromatic leukodystrophy) H000887_01 J03077 78575 PSAP immunology 0.0585383 1.205
2174 LEU_UP_h Peng_et_al_2002 H010777_01 Info Unc119 (C.elegans) homolog H010777_01 AF028789 81728 UNC119 0.0677067 1.248
2175 LEU_UP_h Peng_et_al_2002 H014131_01 Info Microtubule-associated proteins 1A/1B light chain 3 H014131_01 NM_022818 121849 MAP1A/1BLC3 0.0790174 1.225
2176 LEU_UP_h Peng_et_al_2002 H002361_01 Info Casein kinase 1, gamma 2 H002361_01 U89896 181390 CSNK1G2 0.0815742 0.849
2177 LEU_UP_h Peng_et_al_2002 H000564_01 Info Protein kinase C binding protein 1 H000564_01 AB032951 75871 PRKCBP1 0.0986503 0.835
2178 LEU_UP_h Peng_et_al_2002 H000999_01 Info Glycosylphosphatidylinositol specific phospholipase D1 H000999_01 L11702 272529 GPLD1 ADP-Ribosylation Factor 0.0992549 1.126
2179 LEU_UP_h Peng_et_al_2002 H000172_01 Info Kinesin-like 6 (mitotic centromere-associated kinesin) H000172_01 U63743 69360 KNSL6 0.1008966 0.82
2180 LEU_UP_h Peng_et_al_2002 H011237_01 Info Methionine-tRNA synthetase H011237_01 X94754 279946 MARS Aminoacyl-tRNA synthetases, Methionine metabolism, Selenoamino acid metabolism 0.1030499 0.862
2181 LEU_UP_h Peng_et_al_2002 H002491_01 Info Bone morphogenetic protein 1 H002491_01 NM_006129 1274 BMP1 development 0.1079128 0.821
2182 LEU_UP_h Peng_et_al_2002 H002418_01 Info Fc fragment of IgE, low affinity II, receptor for (CD23A) H002418_01 M15059 1416 FCER2 immunology 0.1086867 1.218
2183 LEU_UP_h Peng_et_al_2002 H000998_01 Info Solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 H000998_01 AB018010 79748 SLC3A2 Perou’s – Intrinsic – Breast-Cancer-Genes 0.1156436 0.843
2184 LEU_UP_h Peng_et_al_2002 H003890_01 Info Myelin associated glycoprotein H003890_01 M29273 1780 MAG 0.1166451 1.147
2185 LEU_UP_h Peng_et_al_2002 H012158_01 Info Upregulated by 1,25-dihydroxyvitamin D-3 H012158_01 S73591 179526 VDUP1 0.1293789 1.193
2186 LEU_UP_h Peng_et_al_2002 H003118_01 Info Interferon regulatory factor 2 H003118_01 NM_002199 83795 IRF2 gene_regulation, transcription 0.1483763 1.175
2187 LEU_UP_h Peng_et_al_2002 H011942_01 Info Activating transcription factor 5 H011942_01 AB021663 9754 ATF5 0.1666639 1.141
2188 LEU_UP_h Peng_et_al_2002 H002429_01 Info Tumor necrosis factor receptor superfamily, member 7 H002429_01 M63928 180841 TNFRSF7 immunology 0.1865182 1.133
2189 LEU_UP_h Peng_et_al_2002 H007340_01 Info Putative translation initiation factor H007340_01 AL050005 150580 SUI1 0.2203743 0.897
2190 LEU_UP_h Peng_et_al_2002 H003820_01 Info Lymphocyte-specific protein tyrosine kinase H003820_01 X05027 1765 LCK Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, IL 2 signaling pathway, IL-7 Signal Transduction, Lck and Fyn tyrosine kinases in initiation of TCR Activation, T Cell Receptor Signaling Pathway, The Co-Stimulatory Signal During T-cell Activation, immunology, signal_transduction, tsonc 0.2266863 0.873
2191 LEU_UP_h Peng_et_al_2002 H001256_01 Info Sialyltransferase 4C (beta-galactosidase alpha-2,3-sialytransferase) H001256_01 X74570 75268 SIAT4C 0.2276302 0.892
2192 LEU_UP_h Peng_et_al_2002 H013590_01 Info Nuclear receptor co-repressor 1 H013590_01 AF044209 144904 NCOR1 Control of Gene Expression by Vitamin D Receptor, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha) 0.2336483 0.899
2193 LEU_UP_h Peng_et_al_2002 H001713_01 Info S100 calcium-binding protein A11 (calgizzarin) H001713_01 D38583 256290 S100A11 Perou’s – Intrinsic – Breast-Cancer-Genes 0.2360494 1.115
2194 LEU_UP_h Peng_et_al_2002 H010167_01 Info GTP cyclohydrolase I feedback regulatory protein H010167_01 NM_005258 83081 GCHFR 0.2423472 1.112
2195 LEU_UP_h Peng_et_al_2002 H000426_01 Info Adaptor protein with pleckstrin homology and src homology 2 domains H000426_01 AB000520 105052 APS 0.252114 1.104
2196 LEU_UP_h Peng_et_al_2002 H009957_01 Info KIAA0770 protein H009957_01 AB018313 9452 KIAA0770 0.2820493 1.119
2197 LEU_UP_h Peng_et_al_2002 H000515_01 Info Lymphoid-restricted membrane protein H000515_01 U10485 40202 LRMP misc 0.2845333 1.106
2198 LEU_UP_h Peng_et_al_2002 H014122_01 Info Poly(rC)-binding protein 3 H014122_01 NM_020528 121241 PCBP3 0.3199569 1.111
2199 LEU_UP_h Peng_et_al_2002 H004471_01 Info Chromosome 22 open reading frame 1 H004471_01 U84894 159538 C22ORF1 0.3224188 0.908
2200 LEU_UP_h Peng_et_al_2002 H012354_01 Info Argininosuccinate synthetase H012354_01 X01630 160786 ASS Alanine and aspartate metabolism, Arginine and proline metabolism, Urea cycle and metabolism of amino groups 0.3231469 1.108
2201 LEU_UP_h Peng_et_al_2002 H008885_01 Info Arginine-glutamic acid dipeptide (RE) repeats H008885_01 AB007927 194369 RERE Catabolic Pathways for Arginine , Histidine, Glutamate, Glutamine, and Proline 0.4084586 0.922
2202 LEU_UP_h Peng_et_al_2002 H003935_01 Info KIAA0922 protein H003935_01 AB023139 37892 KIAA0922 0.4306564 1.134
2203 LEU_UP_h Peng_et_al_2002 H001583_01 Info Isocitrate dehydrogenase 2 (NADP+), mitochondrial H001583_01 X69433 5337 IDH2 Citrate cycle (TCA cycle), Glutathione metabolism, Reductive carboxylate cycle (CO2 fixation) 0.4311395 0.932
2204 LEU_UP_h Peng_et_al_2002 H010281_01 Info KIAA1330 protein H010281_01 AB037751 301242 KIAA1330 0.4359424 0.887
2205 LEU_UP_h Peng_et_al_2002 H009376_01 Info ORF H009376_01 M68864 77868 LOC51035 0.4511731 1.055
2206 LEU_UP_h Peng_et_al_2002 H009071_01 Info HS1 binding protein H009071_01 U68566 15318 HAX1 0.4562948 0.927
2207 LEU_UP_h Peng_et_al_2002 H002039_01 Info Phosphoenolpyruvate carboxykinase 2 (mitochondrial) H002039_01 X92720 75812 PCK2 Citrate cycle (TCA cycle), Pyruvate metabolism 0.4857451 0.932
2208 LEU_UP_h Peng_et_al_2002 H004208_01 Info Excision repair cross-complementing rodent repair deficiency, complementation group 2 (xeroderma pig H004208_01 AF041410 99987 ERCC2 0.5075942 1.062
2209 LEU_UP_h Peng_et_al_2002 H007025_01 Info Homo sapiens mRNA; cDNA DKFZp434H2418 (from clone DKFZp434H2418) H007025_01 AL133636 274252 0.5107696 1.077
2210 LEU_UP_h Peng_et_al_2002 H000840_01 Info Signal sequence receptor, beta (translocon-associated protein beta) H000840_01 NM_003145 74564 SSR2 0.5124039 0.937
2211 LEU_UP_h Peng_et_al_2002 H007319_01 Info Histone deacetylase 5 H007319_01 NM_005474 9028 HDAC5 Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Regulation of PGC-1a 0.5427846 1.062
2212 LEU_UP_h Peng_et_al_2002 H004277_01 Info KIAA0801 gene product H004277_01 AB018344 17585 KIAA0801 0.6020006 0.947
2213 LEU_UP_h Peng_et_al_2002 H010714_01 Info Chloride channel 6 H010714_01 X83378 211614 CLCN6 0.6039191 0.953
2214 LEU_UP_h Peng_et_al_2002 H006566_01 Info Surfeit 1 H006566_01 Z35093 3196 SURF1 immunology 0.6139479 1.054
2215 LEU_UP_h Peng_et_al_2002 H007902_01 Info FE65-LIKE 2 H007902_01 AB018247 173103 FE65L2 0.6201659 0.951
2216 LEU_UP_h Peng_et_al_2002 H000390_01 Info Microsomal glutathione S-transferase 2 H000390_01 U77604 81874 MGST2 Perou’s – Intrinsic – Breast-Cancer-Genes, Glutathione metabolism, pharmacology 0.6454088 1.048
2217 LEU_UP_h Peng_et_al_2002 H015369_01 Info Homo sapiens cDNA FLJ11961 fis, clone HEMBB1001020, highly similar to Homo sapiens mRNA for KIAA0889 H015369_01 AK022023 287469 0.6728969 0.969
2218 LEU_UP_h Peng_et_al_2002 H002427_01 Info Calcium/calmodulin-dependent protein kinase I H002427_01 L41816 184402 CAMK1 Actions of Nitric Oxide in the Heart, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Ca++/ Calmodulin-dependent Protein Kinase Activation, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Effects of calcineurin in Keratinocyte Differentiation, Endocytotic role of NDK, Phosphins and Dynamin, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Links between Pyk2 and Map Kinases, Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Nitric Oxide Signaling Pathway, Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of PGC-1a, Role of MEF2D in T-cell Apoptosis, Signal Dependent Regulation of Myogenesis by Corepressor MITR, Signaling Pathway from G-Protein Families, … 0.6744118 1.052
2219 LEU_UP_h Peng_et_al_2002 H000910_01 Info Solute carrier family 1 (neutral amino acid transporter), member 5 H000910_01 U53347 183556 SLC1A5 immunology 0.7186183 0.971
2220 LEU_UP_h Peng_et_al_2002 H003776_01 Info Aldehyde dehydrogenase 2 family (mitochondrial) H003776_01 X05409 195432 ALDH2 Arginine and proline metabolism, Ascorbate and aldarate metabolism, beta-Alanine metabolism, Bile acid biosynthesis, Butanoate metabolism, Fatty acid metabolism, Glycerolipid metabolism, Glycolysis / Gluconeogenesis, Histidine metabolism, Limonene and pinene degradation, Lysine degradation, Propanoate metabolism, Pyruvate metabolism, Tryptophan metabolism, Valine, leucine and isoleucine degradation, immunology, pharmacology 0.7225282 0.971
2221 LEU_UP_h Peng_et_al_2002 H000419_01 Info Pleckstrin homology, Sec7 and coiled/coil domains 1(cytohesin 1) H000419_01 M85169 1050 PSCD1 ADP-Ribosylation Factor 0.7795723 1.029
2222 LEU_UP_h Peng_et_al_2002 H002850_01 Info Murine leukemia viral (bmi-1) oncogene homolog H002850_01 L13689 431 BMI1 Perou’s – Intrinsic – Breast-Cancer-Genes, The PRC2 Complex Sets Long-term Gene Silencing Through Modification of Histone Tails, immunology, tsonc 0.7846354 0.976
2223 LEU_UP_h Peng_et_al_2002 H007376_01 Info Homo sapiens cDNA: FLJ22071 fis, clone HEP11691 H007376_01 AL049932 326248 0.785212 1.026
2224 LEU_UP_h Peng_et_al_2002 H001506_01 Info Pyrroline-5-carboxylate reductase 1 H001506_01 M77836 79217 PYCR1 Arginine and proline metabolism, Urea cycle and metabolism of amino groups, immunology 0.8073734 0.973
2225 LEU_UP_h Peng_et_al_2002 H002397_01 Info Methylene tetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase H002397_01 X16396 154672 MTHFD2 Glyoxylate and dicarboxylate metabolism, One carbon pool by folate 0.8081788 0.975
2226 LEU_UP_h Peng_et_al_2002 H002721_01 Info Sialyltransferase 1 (beta-galactoside alpha-2,6-sialytransferase) H002721_01 X62822 2554 SIAT1 angiogenesis, metastasis 0.8087218 1.023
2227 LEU_UP_h Peng_et_al_2002 H001939_01 Info BTG family, member 2 H001939_01 U72649 75462 BTG2 BTG family proteins and cell cycle regulation 0.8452859 0.981
2228 LEU_UP_h Peng_et_al_2002 H006441_01 Info Golgi-specific brefeldin A resistance factor 1 H006441_01 AF068755 155499 GBF1 ADP-Ribosylation Factor 0.8714172 0.982
2229 LEU_UP_h Peng_et_al_2002 H000327_01 Info BTB and CNC homology 1, basic leucine zipper transcription factor 1 H000327_01 AB002803 154276 BACH1 0.881473 1.018
2230 LEU_UP_h Peng_et_al_2002 H004001_01 Info Trefoil factor 3 (intestinal) H004001_01 L15203 82961 TFF3 Perou’s – Intrinsic – Breast-Cancer-Genes, Trefoil Factors Initiate Mucosal Healing 0.9010781 0.99
2231 LEU_UP_h Peng_et_al_2002 H001599_01 Info Prepronociceptin H001599_01 U48263 89040 PNOC 0.9577235 1.006
2232 LEU_UP_h Peng_et_al_2002 H002511_01 Info KH-type splicing regulatory protein (FUSE binding protein 2) H002511_01 U94832 91142 KHSRP 0.9705349 0.997
2233 LEU_UP_h Peng_et_al_2002 H008685_01 Info Metallothionein 2A H008685_01 V00594 118786 MT2A 0.9730896 1.006
2234 LEU_UP_h Peng_et_al_2002 H000065_01 Info BCL2/adenovirus E1B 19kD-interacting protein 3-like H000065_01 AL132665 132955 BNIP3L 0.9898676 0.999
2235 p53Pathway_h BioCarta H003112_01 Info Retinoblastoma 1 (including osteosarcoma) H003112_01 L41870 75770 RB1 BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Chaperones modulate interferon Signaling Pathway, Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase RNA component gene hTerc Transcriptional Regulation, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Regulation of transcriptional activity by PML, Telomeres, Telomerase, Cellular Aging, and Immortality, TNFR1 Signaling Pathway, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, immunology, tsonc 0.0008596 0.674
2236 p53Pathway_h BioCarta H002412_01 Info Cyclin-dependent kinase 2 H002412_01 M68520 19192 CDK2 CDK Regulation of DNA Replication, Cell Cycle: G1/S Check Point , Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, immunology, signal_transduction 0.0040171 0.711
2237 p53Pathway_h BioCarta H002789_01 Info Tumor protein p53 (Li-Fraumeni syndrome) H002789_01 NM_000546 1846 TP53 Apoptotic Signaling in Response to DNA Damage, ATM Signaling Pathway, BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Chaperones modulate interferon Signaling Pathway, CTCF: First Multivalent Nuclear Factor, Double Stranded RNA Induced Gene Expression, Estrogen-responsive protein Efp controls cell cycle and breast tumors growth, Hypoxia and p53 in the Cardiovascular system, Overview of telomerase protein component gene hTert Transcriptional Regulation , p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of cell cycle progression by Plk3, Regulation of transcriptional activity by PML, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, DNA_damage, gene_regulation, immunology, transcription, tsonc 0.0273242 1.207
2238 p53Pathway_h BioCarta H002599_01 Info Proliferating cell nuclear antigen H002599_01 M15796 78996 PCNA p53 Signaling Pathway, cell_cycle, gene_regulation, transcription 0.0303031 0.732
2239 p53Pathway_h BioCarta H002149_01 Info Cyclin-dependent kinase inhibitor 1A (p21, Cip1) H002149_01 U03106 179665 CDKN1A ATM Signaling Pathway, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, Effects of calcineurin in Keratinocyte Differentiation, Erythropoietin mediated neuroprotection through NF-kB, Hypoxia and p53 in the Cardiovascular system, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, immunology, tsonc 0.0349766 1.236
2240 p53Pathway_h BioCarta H002323_01 Info Cyclin E1 H002323_01 M74093 9700 CCNE1 Perou’s – Intrinsic – Breast-Cancer-Genes, CDK Regulation of DNA Replication, Cell Cycle: G1/S Check Point , Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, Regulation of p27 Phosphorylation during Cell Cycle Progression, cell_cycle 0.1107382 0.884
2241 p53Pathway_h BioCarta H003605_01 Info BCL2-associated X protein H003605_01 L22474 159428 BAX Apoptotic Signaling in Response to DNA Damage, Ceramide Signaling Pathway, Hypoxia and p53 in the Cardiovascular system, p53 Signaling Pathway, Regulation of BAD phosphorylation, Role of Mitochondria in Apoptotic Signaling, apoptosis, development, immunology 0.253339 0.907
2242 p53Pathway_h BioCarta H001999_01 Info Cyclin D1 (PRAD1: parathyroid adenomatosis 1) H001999_01 X59798 82932 CCND1 Perou’s – Intrinsic – Breast-Cancer-Genes, BTG family proteins and cell cycle regulation, CARM1 and Regulation of the Estrogen Receptor, Cell Cycle: G1/S Check Point , Cyclins and Cell Cycle Regulation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, WNT Signaling Pathway, cell_cycle, tsonc 0.3215316 0.898
2243 p53Pathway_h BioCarta H000475_01 Info Apoptotic protease activating factor H000475_01 NM_013229 77579 APAF1 Apoptotic Signaling in Response to DNA Damage, Caspase Cascade in Apoptosis, D4-GDI Signaling Pathway, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , p53 Signaling Pathway, Role of Mitochondria in Apoptotic Signaling, Stress Induction of HSP Regulation, Trefoil Factors Initiate Mucosal Healing, apoptosis, immunology 0.7764943 0.97
2244 p53Pathway_h BioCarta H006841_01 Info Homo sapiens mRNA; cDNA DKFZp564P073 (from clone DKFZp564P073) H006841_01 AL049301 278577 Apoptotic Signaling in Response to DNA Damage, Ceramide Signaling Pathway, Hypoxia and p53 in the Cardiovascular system, p53 Signaling Pathway, Regulation of BAD phosphorylation, Role of Mitochondria in Apoptotic Signaling, apoptosis, development, immunology 0.7810094 0.98
2245 p53Pathway_h BioCarta H003766_01 Info Mouse double minute 2, human homolog of; p53-binding protein H003766_01 M92424 170027 MDM2 ATM Signaling Pathway, Cell Cycle: G2/M Checkpoint, CTCF: First Multivalent Nuclear Factor, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, p53 Signaling Pathway, Sumoylation by RanBP2 Regulates Transcriptional Repression, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, gene_regulation, transcription, tsonc 0.8018001 0.978
2246 ppargPathway_h BioCarta H002547_01 Info Lipoprotein lipase H002547_01 M15856 180878 LPL Low-density lipoprotein (LDL) pathway during atherogenesis, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Role of PPAR-gamma Coactivators in Obesity and Thermogenesis, Visceral Fat Deposits and the Metabolic Syndrome, Glycerolipid metabolism, immunology 0.0011159 0.719
2247 ppargPathway_h BioCarta H000570_01 Info CREB binding protein (Rubinstein-Taybi syndrome) H000570_01 U47741 23598 CREBBP gene_regulation, transcription 0.0048718 1.469
2248 ppargPathway_h BioCarta H003606_01 Info Retinoid X receptor, alpha H003606_01 U66306 20084 RXRA Basic mechanism of action of PPARa, PPARb(d) and PPARg and effects on gene expression, Control of Gene Expression by Vitamin D Receptor, Degradation of the RAR and RXR by the proteasome, FXR and LXR Regulation of Cholesterol Metabolism, Map Kinase Inactivation of SMRT Corepressor, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells, Role of PPAR-gamma Coactivators in Obesity and Thermogenesis, Transcription Regulation by Methyltransferase of CARM1, Visceral Fat Deposits and the Metabolic Syndrome, development, gene_regulation, transcription 0.0142664 1.308
2249 ppargPathway_h BioCarta H001374_01 Info PPAR binding protein H001374_01 Y13467 15589 PPARBP Perou’s – Intrinsic – Breast-Cancer-Genes, CARM1 and Regulation of the Estrogen Receptor, Control of Gene Expression by Vitamin D Receptor, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Multi-step Regulation of Transcription by Pitx2, Role of PPAR-gamma Coactivators in Obesity and Thermogenesis 0.0333785 0.803
2250 ppargPathway_h BioCarta H000245_01 Info Peroxisome proliferative activated receptor, gamma H000245_01 L40904 100724 PPARG Basic mechanism of action of PPARa, PPARb(d) and PPARg and effects on gene expression, Nuclear Receptors in Lipid Metabolism and Toxicity, Role of PPAR-gamma Coactivators in Obesity and Thermogenesis, Visceral Fat Deposits and the Metabolic Syndrome 0.7837641 0.944
2251 ppargPathway_h BioCarta H003151_01 Info E1A binding protein p300 H003151_01 U01877 25272 EP300 Acetylation and Deacetylation of RelA in The Nucleus, CARM1 and Regulation of the Estrogen Receptor, Cell Cycle: G2/M Checkpoint, Control of Gene Expression by Vitamin D Receptor, Hypoxia and p53 in the Cardiovascular system, Hypoxia-Inducible Factor in the Cardiovascular System, IL-7 Signal Transduction, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Melanocyte Development and Pigmentation Pathway, Multi-step Regulation of Transcription by Pitx2, NFkB activation by Nontypeable Hemophilus influenzae, Pelp1 Modulation of Estrogen Receptor Activity, Role of ERBB2 in Signal Transduction and Oncology, Role of MEF2D in T-cell Apoptosis, Role of PPAR-gamma Coactivators in Obesity and Thermogenesis, TGF beta signaling pathway, Transcription Regulation by Methyltransferase of CARM1, gene_regulation, transcription 0.9607239 1.004
2252 ST_ERK1_ERK2_MAPK_Pathway_h Signalling Transduction KE H002055_01 Info Growth factor receptor-bound protein 2 H002055_01 M96995 296381 GRB2 Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel … 0.0022348 1.459
2253 ST_ERK1_ERK2_MAPK_Pathway_h Signalling Transduction KE H015306_01 Info Core promoter element binding protein H015306_01 NM_001300 285313 COPEB 0.0052134 1.473
2254 ST_ERK1_ERK2_MAPK_Pathway_h Signalling Transduction KE H001868_01 Info Dual specificity phosphatase 9 H001868_01 Y08302 144879 DUSP9 Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases 0.0053314 0.725
2255 ST_ERK1_ERK2_MAPK_Pathway_h Signalling Transduction KE H002763_01 Info Mitogen-activated protein kinase kinase kinase 8 H002763_01 D14497 248 MAP3K8 MAP Kinase Signaling Pathway 0.005954 1.333
2256 ST_ERK1_ERK2_MAPK_Pathway_h Signalling Transduction KE H000309_01 Info CAMP response element-binding protein CRE-BPa H000309_01 L05515 149 H_GS165L15.1 0.0078273 1.479
2257 ST_ERK1_ERK2_MAPK_Pathway_h Signalling Transduction KE H004258_01 Info Elongation factor-2 kinase H004258_01 U93850 259855 HSU93850 Eukaryotic protein translation 0.0132437 0.748
2258 ST_ERK1_ERK2_MAPK_Pathway_h Signalling Transduction KE H002890_01 Info Ribosomal protein S6 kinase, 90kD, polypeptide 1 H002890_01 L07597 149957 RPS6KA1 Cell Cycle: G2/M Checkpoint, Erk1/Erk2 Mapk Signaling pathway, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, MAP Kinase Signaling Pathway, Melanocyte Development and Pigmentation Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of BAD phosphorylation, Role of Erk5 in Neuronal Survival, Transcription factor CREB and its extracellular signals, Phosphatidylinositol signaling system 0.0138896 1.42
2259 ST_ERK1_ERK2_MAPK_Pathway_h Signalling Transduction KE H000612_01 Info Ribosomal protein S6 kinase, 90kD, polypeptide 3 H000612_01 U08316 173965 RPS6KA3 MAP Kinase Signaling Pathway, Signaling Pathway from G-Protein Families, Phosphatidylinositol signaling system 0.0473043 0.79
2260 ST_ERK1_ERK2_MAPK_Pathway_h Signalling Transduction KE H011228_01 Info G protein-coupled receptor kinase 7 H011228_01 AL137615 261828 GPRK7 Perou’s – Intrinsic – Breast-Cancer-Genes, Erk1/Erk2 Mapk Signaling pathway, MAP Kinase Signaling Pathway, Phosphatidylinositol signaling system 0.0572981 1.27
2261 ST_ERK1_ERK2_MAPK_Pathway_h Signalling Transduction KE H000521_01 Info Ribosomal protein S6 kinase, 90kD, polypeptide 2 H000521_01 X85106 301664 RPS6KA2 MAP Kinase Signaling Pathway, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.0604408 1.207
2262 ST_ERK1_ERK2_MAPK_Pathway_h Signalling Transduction KE H003178_01 Info Mitogen-activated protein kinase 3 H003178_01 X60188 861 MAPK3 Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … 0.0986041 1.184
2263 ST_ERK1_ERK2_MAPK_Pathway_h Signalling Transduction KE H002943_01 Info V-raf murine sarcoma viral oncogene homolog B1 H002943_01 M95712 622 BRAF MAP Kinase Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction, tsonc 0.2376595 0.895
2264 ST_ERK1_ERK2_MAPK_Pathway_h Signalling Transduction KE H002405_01 Info Mitogen-activated protein kinase kinase 2 H002405_01 L11285 72241 MAP2K2 Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Bioactive Peptide Induced Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, fMLP induced chemokine gene expression in HMC-1 cells, Human Cytomegalovirus and Map Kinase Pathways, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Phosphorylation of MEK1 by cdk5/p35 down regulates the MAP kinase pathway, Role of MAL in Rho-Mediated Activation of SRF, Role of �-arrestins in the activation and targeting of MAP kinases, Roles of �-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling, Signaling of Hepatocyte Growth Factor Receptor 0.3118803 1.093
2265 ST_ERK1_ERK2_MAPK_Pathway_h Signalling Transduction KE H002565_01 Info TNF receptor-associated factor 3 H002565_01 U21092 297660 TRAF3 CD40L Signaling Pathway, TACI and BCMA stimulation of B cell immune responses., TNFR2 Signaling Pathway, immunology 0.3225034 1.104
2266 ST_ERK1_ERK2_MAPK_Pathway_h Signalling Transduction KE H001974_01 Info BCL2-antagonist of cell death H001974_01 U66879 76366 BAD AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, Ceramide Signaling Pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Phosphoinositides and their downstream targets., Ras Signaling Pathway, Regulation of BAD phosphorylation, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Trefoil Factors Initiate Mucosal Healing, apoptosis, development 0.6985187 0.954
2267 ST_ERK1_ERK2_MAPK_Pathway_h Signalling Transduction KE H002722_01 Info Mitogen-activated protein kinase kinase 1 H002722_01 L11284 3446 MAP2K1 Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … 0.7377933 0.973
2268 ST_ERK1_ERK2_MAPK_Pathway_h Signalling Transduction KE H003711_01 Info Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) H003711_01 M58603 83428 NFKB1 Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Bone Remodelling, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Ceramide Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Corticosteroids and cardioprotection, CXCR4 Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, Free Radical Induced Apoptosis, HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of a … 0.8665095 1.017
2269 ST_ERK1_ERK2_MAPK_Pathway_h Signalling Transduction KE H003163_01 Info CAMP responsive element binding protein 1 H003163_01 M27691 79194 CREB1 Ca++/ Calmodulin-dependent Protein Kinase Activation, Calcium Signaling by HBx of Hepatitis B virus, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia-Inducible Factor in the Cardiovascular System, Inhibition of Huntington\’s disease neurodegeneration by histone deacetylase inhibitors, MAP Kinase Signaling Pathway, Melanocyte Development and Pigmentation Pathway, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Repression of Pain Sensation by the Transcriptional Regulator DREAM, Role of Erk5 in Neuronal Survival, Signaling Pathway from G-Protein Families, Transcription factor CREB and its extracellular signals, Transcription Regulation by Methyltransferase of CARM1, immunology 0.9300928 1.009
2270 ST_ERK1_ERK2_MAPK_Pathway_h Signalling Transduction KE H012856_01 Info MAP kinase-interacting serine/threonine kinase 1 H012856_01 AB000409 5591 MKNK1 Erk1/Erk2 Mapk Signaling pathway, MAP Kinase Signaling Pathway, mTOR Signaling Pathway, p38 MAPK Signaling Pathway , Regulation of eIF4e and p70 S6 Kinase, Phosphatidylinositol signaling system 0.9455231 0.992
2271 ST_ERK1_ERK2_MAPK_Pathway_h Signalling Transduction KE H001715_01 Info Dual specificity phosphatase 4 H001715_01 AL137704 2359 DUSP4 Perou’s – Intrinsic – Breast-Cancer-Genes, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, cell_cycle, cell_signaling 0.9634643 1.004
2272 MAP00710_Carbon_fixation_h GenMAPP H004823_01 Info Aldolase C, fructose-bisphosphate H004823_01 AF054987 155247 ALDOC Carbon fixation, Fructose and mannose metabolism, Glycolysis / Gluconeogenesis, Inositol metabolism, Pentose phosphate pathway 0.001576 0.707
2273 MAP00710_Carbon_fixation_h GenMAPP H003374_01 Info Aldolase A, fructose-bisphosphate H003374_01 M11560 273415 ALDOA Downregulated of MTA-3 in ER-negative Breast Tumors, Carbon fixation, Fructose and mannose metabolism, Glycolysis / Gluconeogenesis, Inositol metabolism, Pentose phosphate pathway, immunology 0.0300936 1.252
2274 MAP00710_Carbon_fixation_h GenMAPP H007138_01 Info Phosphoglycerate kinase {alternatively spliced} [human, phosphoglycerate kinase deficient patient wi H007138_01 S81916 169313 Glycolysis Pathway, Carbon fixation, Glycolysis / Gluconeogenesis, immunology 0.0923463 1.164
2275 MAP00710_Carbon_fixation_h GenMAPP H002872_01 Info Malate dehydrogenase 1, NAD (soluble) H002872_01 D55654 75375 MDH1 Carbon fixation, Citrate cycle (TCA cycle), Glyoxylate and dicarboxylate metabolism, Pyruvate metabolism, Reductive carboxylate cycle (CO2 fixation) 0.2471473 0.895
2276 MAP00710_Carbon_fixation_h GenMAPP H001847_01 Info Glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) H001847_01 M22632 170197 GOT2 Alanine and aspartate metabolism, Alkaloid biosynthesis I, Arginine and proline metabolism, Carbon fixation, Cysteine metabolism, Glutamate metabolism, Novobiocin biosynthesis, Phenylalanine metabolism, Phenylalanine, tyrosine and tryptophan biosynthesis, Tyrosine metabolism, immunology 0.287796 0.905
2277 MAP00710_Carbon_fixation_h GenMAPP H003068_01 Info Pyruvate kinase, muscle H003068_01 M26252 198281 PKM2 Carbon fixation, Glycolysis / Gluconeogenesis, Purine metabolism, Pyruvate metabolism 0.3246109 1.102
2278 MAP00710_Carbon_fixation_h GenMAPP H002150_01 Info Glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) H002150_01 M37400 597 GOT1 Malate-aspartate shuttle, Alanine and aspartate metabolism, Alkaloid biosynthesis I, Arginine and proline metabolism, Carbon fixation, Cysteine metabolism, Glutamate metabolism, Novobiocin biosynthesis, Phenylalanine metabolism, Phenylalanine, tyrosine and tryptophan biosynthesis, Tyrosine metabolism 0.3605272 0.917
2279 MAP00710_Carbon_fixation_h GenMAPP H001549_01 Info Malate dehydrogenase 2, NAD (mitochondrial) H001549_01 AF047470 111076 MDH2 Malate-aspartate shuttle, Shuttle for transfer of acetyl groups from mitochondria to the cytosol, Carbon fixation, Citrate cycle (TCA cycle), Glyoxylate and dicarboxylate metabolism, Pyruvate metabolism, Reductive carboxylate cycle (CO2 fixation), immunology 0.7163304 0.952
2280 drug_resistance_and_metabolism_h BioCarta H001935_01 Info Glyceraldehyde-3-phosphate dehydrogenase H001935_01 U34995 169476 GAPD 0.0001082 1.485
2281 drug_resistance_and_metabolism_h BioCarta H002040_01 Info Epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog) H002040_01 X00588 77432 EGFR Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Keratinocyte Differentiation, Map Kinase Inactivation of SMRT Corepressor, mCalpain and friends in Cell motility, Neuroregulin receptor degradation protein-1 Controls ErbB3 receptor recycling, Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Role of ERBB2 in Signal Transduction and Oncology, Sprouty regulation of tyrosine kinase signals, Telomeres, Telomerase, Cellular Aging, and Immortality, The role of FYVE-finger proteins in vesicle transport, Trefoil Factors Initiate Mucosal Healing, angiogenesis, signal_transduction, tsonc 0.0004362 0.669
2282 drug_resistance_and_metabolism_h BioCarta H003596_01 Info O-6-methylguanine-DNA methyltransferase H003596_01 M29971 1384 MGMT DNA_adducts, DNA_damage 0.0006291 0.667
2283 drug_resistance_and_metabolism_h BioCarta H003112_01 Info Retinoblastoma 1 (including osteosarcoma) H003112_01 L41870 75770 RB1 BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Chaperones modulate interferon Signaling Pathway, Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase RNA component gene hTerc Transcriptional Regulation, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Regulation of transcriptional activity by PML, Telomeres, Telomerase, Cellular Aging, and Immortality, TNFR1 Signaling Pathway, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, immunology, tsonc 0.0008596 0.674
2284 drug_resistance_and_metabolism_h BioCarta H002412_01 Info Cyclin-dependent kinase 2 H002412_01 M68520 19192 CDK2 CDK Regulation of DNA Replication, Cell Cycle: G1/S Check Point , Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, immunology, signal_transduction 0.0040171 0.711
2285 drug_resistance_and_metabolism_h BioCarta H000872_01 Info ATP-binding cassette, sub-family C (CFTR/MRP), member 5 H000872_01 AF104942 108660 ABCC5 0.00423 0.773
2286 drug_resistance_and_metabolism_h BioCarta H002387_01 Info MutS (E. coli) homolog 2 (colon cancer, nonpolyposis type 1) H002387_01 NM_000251 78934 MSH2 DNA_damage, tsonc 0.004273 0.694
2287 drug_resistance_and_metabolism_h BioCarta H000208_01 Info Breast cancer 1, early onset H000208_01 NM_007295 194143 BRCA1 ATM Signaling Pathway, BRCA1-dependent Ub-ligase activity, CARM1 and Regulation of the Estrogen Receptor, Cell Cycle: G2/M Checkpoint, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, DNA_damage, immunology, tsonc 0.009032 0.746
2288 drug_resistance_and_metabolism_h BioCarta H003606_01 Info Retinoid X receptor, alpha H003606_01 U66306 20084 RXRA Basic mechanism of action of PPARa, PPARb(d) and PPARg and effects on gene expression, Control of Gene Expression by Vitamin D Receptor, Degradation of the RAR and RXR by the proteasome, FXR and LXR Regulation of Cholesterol Metabolism, Map Kinase Inactivation of SMRT Corepressor, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells, Role of PPAR-gamma Coactivators in Obesity and Thermogenesis, Transcription Regulation by Methyltransferase of CARM1, Visceral Fat Deposits and the Metabolic Syndrome, development, gene_regulation, transcription 0.0142664 1.308
2289 drug_resistance_and_metabolism_h BioCarta H001848_01 Info Glutathione S-transferase M1 H001848_01 J03817 324730 GSTM1 Glutathione metabolism, immunology, pharmacology 0.018415 0.773

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