Chauhan Lab
Anjali Chauhan, PhD – Assistant Professor
Education & Training
BS Pharmacy, Ram-Eesh Institute of Vocational and Technical Education, – Greater Noida, India
MS Pharmacology, All India Institute of Medical Sciences – New Delhi, India
PhD Pharmacology, All India Institute of Medical Sciences – New Delhi, India
Areas of Interest
Clinical interests: ischemic stroke and aging
Research interests: molecular mechanisms involved in aging, mechanisms and therapeutic targets for management of ischemic stroke
Research & Experience
During my doctoral training, I explored potential therapeutic targets for the management of ischemic stroke and found that the immunosuppressive agents, rapamycin and mycophenolate mofetil effectively ameliorated the brain damage in ischemic injury. The protection was a consequence of the reduction of inflammation and oxidative stress induced by these agents.
Besides investigating potential therapeutics for ischemic stroke, I am exploring the contribution of peripheral immune cells in the process of aging as well as ischemic stroke. I found that with age, the spleen harbors more myeloid cells that then migrate to the site of injury and aggravate brain damage after ischemic stroke. Additionally, my other research projects focus on investigating the role of TGF-beta Activated Kinase inhibition and CD13 in acute stroke and investigating the role of GDF11 in aging and its effect on stroke outcomes in older animals.
Research Assistants
Dustin Nguyen
Education & Training
BS Biochemistry with minor in Computer Sciences, The University of Texas – Austin, TX (2023)
Cassandra Hall
Education & Training
BS Neuroscience & Psychology, The University of Texas at Dallas – Richardson, TX (2023)