Lin Lab
Hung Wen (Kevin) Lin, PhD – Professor
Education & Training
BS Biochemistry, University of Wisconsin-Madison – Madison, WI
PhD Pharmacology, Southern Illinois University School of Medicine – Springfield, IL
Postdoc Neurology, University of Miami, Miller School of Medicine – Miami, FL
Areas of Interest
Clinical interests: stroke, brain ischemia, fatty acid metabolism, and Alzheimer’s Disease
Research interests: neurovascular coupling, blood-brain barrier, and protein arginine methyltransferase
Research & Experience
My expertise is in the field of neurovascular coupling and the blood-brain barrier in the field of ischemia/stroke, and Alzheimer’s disease. We are currently heavily vested in protein arginine methyltransferases in the central nervous system. I have dedicated over 20 years to investigate the cerebral vasculature with the focus on stroke, brain ischemia, and fatty acid metabolism to examine the connections between the heart and brain.
Recently, we have uncovered various roles of protein arginine methyltransferases in the brain. These can have direct consequences affecting mitochondrial function, inflammation regulation, and functional/behavioral deficits. With my expertise in neurovascular coupling and protein arginine methyltransferases in the brain, I am confident that we will uncover other novel aspects of these enzymes (i.e. arginine methylators, lipid mediators), which are still largely unknown and may extend beyond pathologies related to cancer with direct implications in brain injury, stroke, Alzheimer’s disease and other neurodegenerative diseases.
Cristiane Citidine, PhD – Senior Program Manager
Education & Training
PhD Molecular Biology, University of Brasilia – Brazil
Areas of Interest
Research interests: Alzheimer’s Disease, stroke, traumatic brain injury, and cerebral blood flow
Research & Experience
I have around 6 years of experience in brain blood flow that includes stroke and the ACA model, AD, and TBI.
Hobbies & Interests
Music, dance, and theatre
Julia Zaccarelli Magalhaes, PhD – Postdoctoral Research Fellow
Education & Training
BS Biological Science, Mackenzie Presbyterian University – Brazil
MS Neuropharmacology, University of Sao Paulo – Brazil
PhD Neuropharmacology, University of Sao Paulo – Brazil
Areas of Interest
Research interests: Alzheimer’s Disease, neurodegenerative diseases, memory and cognition impairment, and neuropharmacology
Research & Experience
Previous works with behavioral and neurochemical alterations of GABAergic, cholinergic, and serotoninergic drugs, as well with the effects of postpartum depression on both mother and offspring in a rodent model. Currently work with cerebral vasculature and its association with Alzheimer’s disease and other diseases of the central nervous system.
Hobbies & Interests
Traveling, music, and cinema
Mariana S Berto Udo, PhD – Postdoctoral Research Fellow
Education & Training
BS Pharmaceutical Science with specialty in Toxicology, State University of Campinas – Brazil
MS Neurotoxicology, University of Sao Paulo – Brazil
PhD Neurotoxicology, University of Sao Paulo – Brazil
Areas of Interest
Research interests: brain vasculature and neurodegenerative disease
Research & Experience
I have experience with animal behavior with developmental toxicology due to pesticide exposure/sub-acute intoxication; neuronal injuries and degeneration due to drug abuse; development of biomarkers and drug delivery system (DDS) for treatment of age-related macular degeneration; and biochemical basic research on neurodegeneration related to vascular dementias, including Alzheimer’s disease.
Hobbies & Interests
DIY, crafts, and electronics
Research Assistants
Luiz Matuguma – Research Assistant
Education & Training
BS Food Science, University of Sao Paulo – Brazil