Publications

Concha-Marambio, L., Pritzkow, S., Shahnawaz, M. and Soto, C. (2023) Seed Amplification Assay (SAA) for detection of pathologic αSynuclein aggregates in cerebrospinal fluid. Nature Protocols 18(4):1179-1196.

Concha-Marambio, L., Weber, S., Farris, C.M., Dakna, M., Lang, E., Wicke, T., Ma, Y., Starke, M., Ebentheuer, J., Sixel-Döring, F., Muntean, M.L., Schade, S., Trenkwalder, C., Soto, C. and Mollenhauer, B. (2023) Accurate Detection of α-Synuclein Seeds in Cerebrospinal Fluid from Isolated Rapid Eye Movement Sleep Behavior Disorder and Patients with Parkinson’s Disease in the DeNovo Parkinson (DeNoPa) Cohort. Movement Disorders 38(4):567-578.

Siderowf, A., Concha-Marambio, L., Lafontantc, D.E., Farris, C.M., Mab, Y., Urenia, A., Nguyen, H., Alcalay, R.N., Chahine, L.M., Foroud, T., Galasko, D., Kieburtz, K., Merchant, K., Mollenhauer, B., Poston, K.L., Seibyl, J., Simuni, T., Tanner, C.M., Weintraub, D., Videnovic, A., Choi, S.H., Kurth, R., Caspell-Garcia, C., Coffey, C.S., Frasier, M., Oliveira, L., Sherer, T., Marek, K. and Soto, C. (2023) Assessment of heterogeneity among participants in the Parkinson’s Progression Markers Initiative cohort using α-synuclein seed amplification: a cross-sectional study. Lancet Neurology 22(5):407-417.

Soto, C. (2024) The α-Synuclein Seed Amplification Technology for Parkinson’s disease and related Synucleinopathies. Trends Biotechnology 42(7):829-841.

Lashuel, H.A., Surmeier, D.J., Simuni, T., Merchant, K., Caughey, B., Soto, C., Fares, M.B., Heym, R., and Melki, R. (2024) Advancing Clinical Use of Alpha-Synuclein Seed Amplification Assays: The Imperative of Data Sharing and Collaboration. Science Advances (In press)

Soto, C., Mollenhauer, B., Hansson, O., Kang, U.J., Alcalay, R.N., Standaert, D., Trenkwalder, C., Marek, K., Galasko, D. and Poston, K. (2024) A Biological Definition of Neuronal and Glial Synucleinopathies: Needs, Challenges and Opportunities. Nature Medicine (In press)