Lymphatic Contribution to Progressive Peripheral Vascular Disease and Ulceration
Status: Active & Enrolling Synopsis: Synopsis: To determine the association if any between early stage lower extremity venous reflux or peripheral arterial disease with lymphatic disease.
LEOPARD: Multicenter, Observational, Post-Market, Real-World Study to Assess Outcomes of Patients Treated with the AFX® System Compared to other EVAR Devices for Endovascular Abdominal Aortic Aneurysm Repair LEOPARD: Looking at EVAR Outcomes by Primary Analysis of Randomized Data. PI: Harlin
Status: Active, Not Enrolling Synopsis: The objective of this post-market multicenter randomized observational study is to evaluate Endologix AFX endovascular AAA system with anatomical fixation against other approved Endovascular systems with proximal fixation.
PAIN (Postoperative Analgesia INvestigation)
PI: Charlton-Ouw Synopsis: A randomized controlled trial evaluating efficacy of local anesthetics in managing perioperative pain
Plasma DNA Study PI: Banki Synopsis: This study evaluates plasma DNA in patients with thoracic malignancies and with visceral malperfusion
IVC Filter Retrieval Program PI: Charlton-Ouw Synopsis: A prospective research and quality improvement project analyzing the efficacy and cost-effectiveness of a dedicated IVC filter retrieval team
SAPPHIRE (Stenting and Angioplasty with Protection in Patients at High Risk for Endarterectomy) PI: Azizzadeh Synopsis: This study tracks outcomes in patients after carotid artery angioplasty and stenting
Medtronic DISSECTION Trial PI: Azizzadeh Synopsis: Evaluation of the Medtronic Valiant Thoracic Stent-Graft for acute complicated type B aortic dissection
Medtronic RESCUE Trial PI: Azizzadeh Synopsis: Evaluation of Medtronic Valiant Thoracic Stent-Graft for Traumatic Aortic Injury
Plasma DNA in Organ Malperfusion PI: Banki Synopsis: Evaluating plasma DNA in patients who develop organ malperfusion syndrome after surgical repair for aortic aneurysm or dissection
Figure 8 study (Multi-Center Prospective Study to Demonstrate the Usability, Safety and Efficacy of the Figure 8 Surgical Sternotomy Closure Device) PI: Estrera Synopsis: The purpose of this study is to demonstrate theFigure 8 Surgical Sternotomy Closure Device is safe, effective and easy to use for closing the sternum after a heart or lung surgical procedure.
PRICE (Propaten Randomized Investigation on Cost-benefit and Efficacy) PI: Charlton-Ouw Synopsis: A randomized controlled trial to evaluate the efficacy of anticoagulant bonded hemodialysis arteriovenous grafts
Gore CTAG Aneurysm Trial PI: Estrera Synopsis: Evaluation of the Gore CTAG Endoprosthesis for descending thoracic aortic aneurysms
Gore CTAG Trauma PI: Azizzadeh Synopsis: Evaluation of the Gore CTAG Endoprosthesis for traumatic aortic injury
HARVEST PI: Charlton-Ouw Synopsis: Pivotal Study of the Safety and Effectiveness of Autologous Bone Marrow Aspirate Concentrate (BMAC) for the treatment of Critical Limb Ischemia due to Peripheral Arterial Occlusive Disease
Specialized Center for Clinically-Oriented Research in Aortic Diseases. We are actively involved in the NIH-funded specialized center grant (SCCOR) in collaboration with Dr. Dianna Milewicz in the Department of Medicine. Drs. Safi and Estrera are co-investigators on the main clinical project, and Dr. Miller is Principal Investigator of the Biostatistics core. This project has total direct costs of approximately $6 million and is already producing major findings such as those reported recently in Nature Genetics.