April 6, 2023

Hancock’s Headlines: Texas Therapeutics Institute

When the COVID pandemic hit, the Texas Therapeutics Institute sprung into action to develop therapies for patients suffering from the virus. Not only have they developed drugs to help fight COVID, but they are also developing neurological drugs to help…

January 3, 2022

An earns National Academy of Inventors fellowship

Zhiqiang An, PhD, professor and director of the Texas Therapeutics Institute of the Brown Foundation Institute of Molecular Medicine and Graduate  School faculty member, has been named a fellow of the National Academy of Inventors (NAI), the organization announced Dec….

November 3, 2021

GW Researchers Identify Molecule That Blocks Immune Cells from Killing Breast Tumors

George Washington University researchers have identified a key molecule in certain kinds of breast cancers that prevent immune cells from entering tumors and killing the cancer cells inside—a finding that could pave the way toward new treatments for some aggressive…

June 16, 2021

Research on antibody-drug conjugates shows promise in fighting breast cancer

Research from the lab of Kyoji Tsuchikama, PhD, assistant professor in the Texas Therapeutics Institute at The Brown Foundation Institute of Molecular Medicine, on a new potential treatment for combating breast cancer has been published in the June edition of Nature Communications. “Breast tumors…

June 15, 2021

Could a Nasal Spray of Designer Antibodies Help to Beat COVID-19? NIH Director’s Blog

There are now several monoclonal antibodies, identical copies of a therapeutic antibody produced in large numbers, that are authorized for the treatment of COVID-19. But in the ongoing effort to beat this terrible pandemic, there’s plenty of room for continued…

June 4, 2021

Antibody-laden nasal spray could provide COVID protection — and treatment

A nasal spritz of a designer antibody offers strong protection against variants of the coronavirus SARS-CoV-2 — at least in mice1. Since the early days of the pandemic, scientists have been developing antibodies as treatments for COVID-19. Today, several such…

June 3, 2021

New IgM antibodies administered intranasally to fight COVID-19 more potent than commonly used ones

A nasal therapy, built upon on the application of a new engineered IgM antibody therapy for COVID-19, was more effective than commonly used IgG antibodies at neutralizing the COVID-19 virus in animal models, according to research recently published by The…

April 1, 2021

Study finds why some cancer drugs may be ineffective

A possible explanation for why many cancer drugs that kill tumor cells in mouse models won’t work in human trials has been found by researchers with The University of Texas Health Science Center at Houston (UTHealth) School of Biomedical Informatics…

January 28, 2021

New antibody therapies found to potentially fight COVID-19

Researchers at McGovern Medical School and The University of Texas Medical Branch at Galveston (UTMB Health) have discovered a potential new antibody therapy for COVID-19. The study was published in Nature Communications. Antibodies are proteins that allow the body to fight viruses such as SARS-CoV-2,…

January 20, 2020

UTSW Study Links Alzheimer’s-Related Protein To Diabetes And Obesity

A new study found a protein linked to Alzheimer’s Disease also contributes to problems with diabetes and obesity. It’s called the amyloid precursor protein or APP. That’s the same amyloid believed to form plaque that may cause cognitive decline. The study, published in Nature…