“UT Health EM Faculty lead and participate in nearly 75 active projects, including a variety of clinical trials and observational studies. Nearly 1/3 of these are funded by government or private sponsors.” A sample of these projects are shown below.
1. Neurological Emergencies Treatment Trials Southeast Texas Clinical Site Hub UT Health is one of the largest enrolling sites for the NIH-funded Neurological Emergencies Treatment Trials (NETT) Network which is being coordinated by the University of Michigan. Southeast NETT (housed at UT) is led by Dr. Jones, which helps to conduct multiple large-scale trials to reduce the burden of very acute injuries and illnesses affecting the brain, spinal cord, and peripheral nervous system.
2. Using Saline for Myofascial Pain Syndromes (USA MPS) This study is a prospective, randomized, double-blinded trial involving adult patients diagnosed with Myofascial Pain Syndromes (MPS). The purpose of this research study is to compare if there is a therapeutic difference between trigger point injections of normal saline and conventional drug mix (local anesthetsic + steroid) in treating MPS. In particular, we will find out about the pain level and duration before and after injection. PI: Carlos Roldan, MD
3. Myocardial Infarction Analytic Outcomes Evaluation This observational cardiovascular study involves assessing every MI in Dallas County, Texas to compare outcome metrics and clinical interventions across 35 PCI facilities, with the goal of improving evidence leading to reduced time-to-treat and developing the largest integrated system of care in U.S. PI: James Langabeer, Funding Agency: American Heart Association
4. Vapotherm High Flow Therapy compared to Non-invasive Positive Pressure Ventilation in the treatment of Respiratory Failure in the Emergency Department. The overall objective of this study is to determine iv Vapotherm high flow nasal cannula therapy (HFT), when used to treat respiratory failure in the ED, is at least equivalent to the current standard of care for non-invasive ventilator support, non-invasive positive pressure mask ventilation (NIPPV). Moreover, this study will investigate the potential that HFT has possible advantages over NIPPV, such as decreased time to patient stability from respiratory failure, and the ease of use as a first line intervention for respiratory failure in the ED environment. PI: Dr. Pratik Doshi
5. Measuring and Forecasting Emergency Department Crowding: An Extensible Simulation Framework: The overall goal of this project will be to develop and validate and extensible framework to support evidence-based decision making for managing emergency department (ED) patient flow. PI Dr. Nathan Hoot
6. Smoking Intervention with Trauma Patients in the Emergency Department To improve the rate of smoking cessation interventions by healthcare providers treating patients in the ED and in the inpatient trauma service. PI: Dr. Mandy J. Hill