Time-Dependent Headache Medication Effectiveness Study

Most patients with cluster headache experience the episodic form, in which headaches occur at least every other day for weeks to months before ceasing for at least 3 consecutive months each year. Patients typically start treatments when their headaches begin and discontinue them when the headaches subside.

This study does not introduce new treatments for cluster headache. Rather, it aims to monitor patients’ typical treatments throughout one headache cycle. This study differs itself from other surveys and clinical trials by focusing on several other factors like timing, doses, and effectiveness across different medications that can then be compared. Participation involves an initial online survey followed by a 3-week-long daily online headache diary to record headache occurrences.

To qualify you must:

1. Be at least 18 years of age
2. Have episodic cluster headache
3. Have headaches that will last at least 3 more weeks (based on how long your headache cycles usually last)

If you are interested in the Vitamin D study for cluster headache, please contact the research team at (713) 486-7771 or email us at nctt.wec@uth.tmc.edu for more information.

The enrollment process will require a 15-minute initial phone call with the study coordinator or a research nurse after completing the initial interest survey, followed by a 30-minute phone call with the principal investigator Dr. Mark Burish, if necessary.