My professional interests are focusing on clinical and didactic education of residents and students. I am also available to provide neuroimaging support for projects from other departments.
Vascular imaging, clinical trial core lab imaging, spine intervention, education.
Past Grant Support
W81XWH-11-1-0460 under the direction of Dr. Charles S. Cox, Jr. in Pediatric Surgery. Early Biomarkers of Autism Spectrum Disorders in Infants with Tuberous Sclerosis. Major focus on autism. Start date 6/11/11 – End date 5/31/14. $47,437.50
Current Grant Support
SanBio, Inc – Image Analysis Center. Principal Investigator
Ponnada Narayana, MD. Co-Investigator: Clark Sitton, MD (3%
effort).
Sunovian/SanBio, Inc – Image Analysis Center. Principal
Investigator: Ponnada Narayana, MD. Co-Investigator: Clark Sitton,
MD (3% effort).
Optimizing Patient’s Selection for Endovascular Treatment in Acute
Ischemic Stoke (SELECT). Principal Investigator: Amrou Sarraj,
MD, Department of Neurology, UTMSH. Co-Investigator: Clark
Sitton, MD (3% effort).
Current Research Support
HSC-MS-14-0804 – “FIELD TRIALS OF NOVEL 3D CT IMAGE
RECONSTRUCTION ALGORITHMS DEVELOPED BY
ITOMOGRAPHY FOR NEUROLOGICAL APPLICATIONS”
ABSTRACTS:
1. Simonetta AB, Supsupin E, Sitton C: Retropharyngeal Fluid as a Manifestation of Unsuspected Vascular Injury in Patients Receiving MR Examination of the Cervical Spine After Trauma. American Society of Neuroradiology (ASNR) 47th Annual Meeting, Vancouver, British Columbia, Canada, May 16 -21, 2009.
2. Jobanputra K, Simonetta AB, Riascos R, Sitton C: ASPECTS Reporting: Standardizing CT brain Stroke Protocol Evaluation to Better Patient Triage, Enhance Final Outcomes and Promote Research. Presented at the 55th American Society of Neuroradiology (ASNR), Long Beach, CA, April 24-27.
Referreed Articles in Journals:
1. Chaljub G, Johnson RF, Johnson RF, Sitton CW: Unusually exuberant hyperostosis frontalis interna: MRI. Neuroradiology 1999 Jan:41(1):44-5.
2. Hou P, Hasan PM, Sitton CW, Wolinsky JS, Narayana PA: Phase-Sensitive T1 Inversion Recovery Imaging: A Time-Efficient Interleaved Technique for Improved Tissue Contrast in Neuroimaging. Am J Neuroradiol 2005 26: 1432-1438.
3. Illoh I, Sitton CW: Acute Posterior Multifocal Placoid Pigment Epitheliopathy after Cerebral Sinus Thrombosis. Brain 2007.
4. Koenig MK, Sitton CW, Wang M, Slopis JM. Central nervous system complications of blastic hyperleukocytosis in childhood acute lymphoblastic leukemia: diagnostic and prognostic implications. J Child Neurol. 2008 Nov;23(11):1347-52. PMID: 18984849
5. Bektas H, Wu TC, Kasam M, Harun N, Sitton CW, Grotta JC, Savitz SI. Increased blood-brain barrier permeability on perfusion CT might predict malignant middle cerebral artery infarction. Stroke. 2010 Nov;41(11):2539-44. Epub 2010 Sep 16. PMID: 20847316
6. Supsupin EP, Choi JM, Bonfante-Mejia EE, Sitton CW, Hochhauser L: Bilateral Absence of the Common Carotid Arteries with Separate Origins of the Internal and External Carotid Arteries Detected by CT Angiography: Case Report. Neurographics, 2:1, March 2012, pp. 44-46(3).
7. Sarraj A, Barreto AD, Albright K, Sitton C, Choi, J, Lutzker SL, Bibars W, Martin-Schild S, Saver J, Liebeskind DS, Gupta R, Grotta JC, Savitz S: Optimizing Prediction Scores for Poor Outcome After Intra-arterial Therapy for Anterior Circulation Acute Ischemic Stroke. Stroke. 2013;43:A205. PMID: 23929748
8. Wu TC, Sitton C, Potter A, Bowry R, Sahota P, Cai C, Hui P, Chen Z, Gonzales N, Barreto A, Lopez G, Grotta JC, Savitz SI. CTP infarct core may predict poor outcome in stroke patients treated with IV t-PA. J Neurol Sci. 2014 May 15;340(1-2):165-9. 2014 Mar 18. PMID: 24694764
9. Sarraj A, Sangha N, Hussain MS, Wisco D, Vora N, Elijovich L, Goyal N, Abraham M, Mittal M, Feng L, Wu A, Janardhan V, Nalluri S, Yoo AJ, George M, Edgell R, Shah RJ, Sitton C, Supsupin E, Bajgur S, Denny MC, Chen PR, Dannenbaum M, Martin-Schild S, Savitz SI, Gupta R. Endovascular Therapy for Acute Ischemic Stroke With Occlusion of the Middle Cerebral Artery M2 Segment. JAMA Neurol. 2016 Nov 1;73(11):1291-1296. doi: 10.1001/jamaneurol.2016.2773, PMID 27617425
10. Patel RP, Sitton CW, Ketonen LM, Hou P, Johnson JM, Romo S, Fletcher S, Shah MN, Kerr M, Zaky W, Rytting ME, Khatua S, Sandberg DI. Phase-contrast cerebrospinal fluid flow magnetic resonance imaging in qualitative evaluation of patency of CSF flow pathways prior to infusion of chemotherapeutic and other agents into the fourth ventricle. Childs Nerv Syst. 2018 Mar;34(3):481-486. doi: 10.1007/s00381-017-3669-6. Epub 2017 Nov 23. PMID: 29170836
11. Sarraj A, Hassan A, Savitz SI, Grotta JC, Cai C, Parsha KN, Farrell CM, Imam B, Sitton CW, Reddy ST, Kamal H, Goyal N, Elijovich L, Reishus K, Krishnan R, Sangha N, Wu A, Costa R, Malik R, Mir O, Hasan R, Snodgrass LM, Requena M, Graybeal D, Abraham M, Chen M, McCullough LD, Ribo M. Endovascular Thrombectomy for Mild Strokes: How Low Should We Go? Stroke. 2018 Oct;49(10):2398-2405. doi: 10.1161/STROKEAHA.118.022114. PMID: 30355094
12. Haque ME, Gabr RE, George SD, Boren SB, Vahidy FS, Zhang X, Arevalo OD, Alderman S, Narayana PA, Hasan KM, Friedman ER, Sitton CW, Savitz SI. Serial Cerebral Metabolic Changes in Patients With Ischemic Stroke Treated With Autologous Bone Marrow Derived Mononuclear Cells. Front Neurol. 2019 Feb 25;10:141. doi: 10.3389/fneur.2019.00141. eCollection 2019. PMID: 30858820
13. Haque ME, Gabr RE, Hasan KM, George S, Arevalo OD, Zha A, Alderman S, Jeevarajan J, Mas MF, Zhang X, Satani N, Friedman ER, Sitton CW, Savitz S. Ongoing Secondary Degeneration of the Limbic System in Patients With Ischemic Stroke: A Longitudinal MRI Study. Front Neurol. 2019 Mar 5;10:154. doi: 10.3389/fneur.2019.00154. eCollection 2019. PMID: 30890995
14. Bonfante E, Calle S, Solomon N, Jagolino A, Cai C, Arevalo-Espejo O, Riascos R, Sitton C. Development of a Standardized Grading Scale for Atherosclerotic Disease of the Head and Neck. J Comput Assist Tomogr. 2019 Jul/Aug;43(4):533-538. doi: 10.1097/RCT.0000000000000880.PMID: 31162236
15. Sarraj A, Hassan AE, Savitz S, Sitton C, Grotta J, Chen P, Cai C, Cutter G, Imam B, Reddy S, Parsha K, Pujara D, Riascos R, Vora N, Abraham M, Kamal H, Haussen DC, Barreto AD, Lansberg M, Gupta R, Albers GW. Outcomes of Endovascular Thrombectomy vs Medical Management Alone in Patients With Large Ischemic Cores: A Secondary Analysis of the Optimizing Patient’s Selection for Endovascular Treatment in Acute Ischemic Stroke (SELECT) Study. JAMA Neurol. 2019 Jul 29. doi: 10.1001/jamaneurol.2019.2109. [Epub ahead of print] PMID: 31355873
16. McCarty JL, Leung LY, Peterson RB, Sitton CW, Sarraj A, Riascos RF, Brinjikji W. Ischemic Infarction in Young Adults: A Review for Radiologists. Radiographics. 2019 Oct;39(6):1629-1648. doi: 10.1148/rg.2019190033. PMID: 31589580
17. Bonfante E, Calle S, Solomon N, Jagolino A, Cai C, Espejo O, Riascos R, Sitton C. Development of a Standard Grading Scale for Atherosclerotic Disease of the Head and Neck Journal of Computer Assisted Tomography. Publish ahead of print ():, May 2019 DOI: 10.1097/RCT. 0000000000000880, Issn Print: 0363-8715, Publication Date: 2019/05/01
OTHER PROFESSIONAL COMMUNICATIONS:
PRESENTATIONS:
1. Hemostasis of Hypervascular Spinal Tumors with Preoperative Embolization and/or Intraoperative Cryacoagulation. Presented at the 98th Annual Meeting of the American Roentgen Ray Society, Apr 26 – May 1, 1998, San Francisco, CA.
2. Spondylodiscitis: Radiologic Workup and Intervention. Texas Radiology Course VIII by UTMB – 1999 Update: Neuroradiology, Pediatric and musculoskeletal Imaging, Feb 5 –7, 1999, Westin Galleria, Houston, TX.
3. Bonfante EE, Shaltoni HM, Albright KC, Khaja AM, Sitton CW, Grotta JC, Cacayorin ED: Old Microhemorrhage Is Not a Risk Factor for Hemorrhagic Transformation of Acute Ischemic Stroke Treated with Thrombolytic Therapy. Presented at the American Society of Neuroradiology (ASNR) 44th Annual Meeting, April 29 – May 5, 2006, San Diego, CA.
4. Supsupin E, Albright K, Shaltoni H, Bonfante E, Sitton CW, Hochhauser L, Grotta J, Cacayorin E: Baseline MR Perfusion/Diffusion Weighted Imaging Mismatch Correlated with Subsequent Extent of Ischemic Infarct. Presented at the 44th Annual Meeting of the American Society of Neuroradiology (ASNR), San Diego, California, April 29 – May 5, 2006.
5. Supsupin E, Shaltoni H, Bonfante E, Sitton CW, Hochhauser L, Cacayorin E. Extraaxial Plasmacytoma Mimicking Meningioma. Oral Presentation as Excerpta Extraordinaire at the 44th Annual Meeting of the American Society of Neuroradiology (ASNR), San Diego, California, May 2006.
6. Shaltoni H, Cacayorin ED, Sitton CW, et al: Treatment of Central Retinal Artery Occlusion with Local Fibrinolysis – A Call for a National Registry. Presented at the American Society of Neuroradiology (ASNR) 44th Annual Meeting, Apr 29 – May 05, 2006 in San Diego, California.
7. Shaltoni H, Cacayorin ED, Sitton CW, et al: TIMI Flow Grade 2b or Higher Predicts Better Outcome After Intra-arterial thrombolysis. Presented at the American Society of Neuroradiology (ASNR) 44th Annual Meeting, Apr 29 – May 05, 2006 in San Diego, California.
8. Supsupin EP, Nguyen JV, Vea RG, Cacayorin ED, Sitton CW: Aberrant Stent Location in the Epidural Space after Illiac Vein Senting: Case Report. Oral Presentation at the American Society for Neuroradiologist (ASNR), New Orleans, Louisiana, May 31 – June 5, 2008.
9. Sitton, CW: Alphabet Soup: MRI, MRA, MRV, CT and Angio Defined The Role of Neuro-Imaging and the Latest Developments. 2nd Intracranial Hypertension Research Foundation Patient Conference, The University of Texas Medical School, Medical School Building, Houston, Texas, June 22, 2008.
10. Sitton, CW: MRI of Cervical Spine Trauma. Texas Radiological Society 96th Annual Scientific Meeting, Diagnostic Radiology Program, Fort Worth, Texas, March 8, 2009.
11. Supsupin EP, Aalbers B, Davis A, Bonfante-Mejia EE, Loenig M, Sitton CW, Hochhauser L: Cerebral Folate Deficiency (CFD): Imaging Findings Before and After Treatment. Oral Presentation at the American Society of Neuroradiology (ASNR), Vancouver, British Columbia, Canada, May 16 – 22, 2009.
12. Potter A, Wu T, Sitton CW: CT Angiography and Clinical Outcome in Acute Ischemic Stroke Patients with Completely Occlusive Proximal Middle Cerebral Artery Lesions Treated with Intravenous Tissue Plasminogen Activator. Presented at the American Society of Neuroradiology (ASNR), Seattle, Washington, June 5 – 9, 2011.
13. Sitton, CW: Modern Neuroimaging on Acute Stroke and TBI. Memorial Hermann Hospital Annual Neuro-ICU Symposium, Houston, Texas, March 5, 2015.
14. Sitton, CW, Supsupin E, Choi J, Friedman E, Sarraj A: A Modification of a Collaterals Scoring System for Improved stratification of Outcome in Acute Ischemic Stroke. Oral Presentation at the 53rd American Society of Neuroradiology (ASNR), Chicago, IL, April 25 – 30, 2015.
15. Dahse, M, Patel, R, Sitton, CW: Evaluation of Cerebrovascular Injuries in Blunt Trauma Patients at a Level 1 Trauma Center; the Usefulness of CT Screening. May 24, 2016
16. Barzin, Dahse, M, Riascos, R, Sitton, CW, Patel, R, Spence: Radiological outcome following traumatic grade 1 injury blunt cerebrovascular injury patients: a retrospective analysis of a trauma center. May 23, 2016
SCIENTIFIC EXHIBITS:
1. Hemostasis of Hypervascular Spinal Tumors with Preoperative Embolization and/or Intraoperative Cryocoagulation. 83rd Scientific Assembly and Annual Meeting of the Radiological Society of North America, Nov 30 – Dec 5, 1997, Chicago, IL.
2. Magnetic Resonance Discography. 83rd Scientific Assembly and Annual Meeting of the Radiological Society of North America, Nov 30 – Dec 5, 1997, Chicago, IL.
3. Hemostasis of Hypervascular Spinal Tumors with Preoperative Embolization and/or Intraoperative Cryocoagulation. 1st Annual Joint Scientific Conference of the American Society of Interventional and Therapeutic Neuroradiology/World Federation of Interventional and Therapeutic Neuroradiology, Sept 12 – 16, 1997, New York, NY.
4. Spinal Angiography and Endovascular Intervention. 1st Annual Joint Scientific Conference of the American Society of Interventional and Therapeutic Neuroradiology/World Federation of Interventional and Therapeutic Neuroradiology, Sept 12 – 16, 1997, New York, NY.
5. Pseudoaneurysms Revisited: Update on Therapeutic Options. 1st Annual Joint Scientific Conference of the American Society of Interventional and Therapeutic Neuroradiology/World Federation of Interventional and Therapeutic Neuroradiology, Sept 12–16, 1997, New York, NY.
6. Endosaccular Occlusion of Pseudoaneurysms. 1st Annual Joint Scientific Conference of the American Society of Interventional and Therapeutic Neuroradiology/World Federation of Interventional and Therapeutic Neuroradiology, Sept 12 –16, 1997, New York, NY.
7. Imaging of Spondylodiscitis. 36th Annual Meeting of the American Society of Neuroradiology (ASNR), May 15 – 21, 1998, Philadelphia, PA.
8. Spinal Angiography and Endovascular Interventions. 36th Annual Meeting of the American Society of Neuroradiology (ASNR), May 15 – 21, 1998, Philadelphia, PA.
9. Spinal Intervention: Techniques of Provocative Pain Testing. 36th Annual Meeting of the American Society of Neuroradiology (ASNR), May 15 – 21, 1998, Philadelphia, PA.
10. Pharyngeal Hemorrhage: Emergency Endovascular Treatment. 36th Annual Meeting of the American Society of Neuroradiology, May 15 – 21, 1998, Philadelphia, PA.
11. Transosseous Radiologic Procedures. 36th Annual Meeting of the American Society of Neuroradiology (ASNR), May 15 – 21, 1998, Philadelphia, PA.
12. Spinal Intervention: Techniques of Provocative Pain Testing. 98th Annual Meeting of the American Roentgen Ray Society, Apr 26 – May 1, 1998, San Francisco, CA.
13. Pharyngeal Hemorrhage: Emergency Endovascular Treatments. 98th Annual Meeting of the American Roentgen Ray Society, Apr 26 – May 1, 1998, San Francisco, CA.
14. Juvenile Angiofibromas: Characteristic Imaging Findings and Endovascular Interventions. 98th Annual Meeting of the American Roentgen Ray Society, Apr 26 – May 1, 1998, San Francisco, CA.
15. Juvenile Angiofibromas: Characteristic Imaging Findings and Endovascular Interventions. 84th Scientific Assembly and Annual Meeting of the Radiological Society of North America, Nov 29 – Dec 4, 1998, Chicago, IL
16. Transosseous Radiological Procedures. 84th Scientific Assembly and Annual Meeting of the Radiological Society of North America, Nov 29 – Dec 4, 1998, Chicago, IL.
17. Pseudoaneurysms Revisited: Update on Therapeutic Options. 84th Scientific Assembly and Annual Meeting of the Radiological Society of North America, Nov 29 – Dec 4, 1998, Chicago, IL.
18. Afflictions of the Pons: Distinctive MR Features Revisited. American Society of Neuroradiology (ASNR) 42nd Annual Meeting, Jun 5 – 11, 2004, Seattle, Washington.
19. Head CT Angiography: Anatomical Review. 43rd Annual Meeting of the American Society of Neuroradiology (ASNR), May 21 – 27, 2005, Toronto, Ontario Canada.
20. Supsupin EP, Bonfante-Mejia EE, Sitton CW: Hydrocephalus: Understanding Evolving Concepts and Treatment Electronic Scientific Exhibit. Presented at the American Society of Neuroradiology (ASNR) 45th Annual Meeting & NER Foundation Symposium 2007, June 9 –
14, 2007, Chicago, IL.
21. Supsupin EP, Bonfante-Mejia EE, Sitton CW, Parikh N, Cacayorin ED, Hochhauser L: Cerebral MR Imaging Evaluation of Preterm Infants: Standardized Assessment and Predicting the Relationship of Common Imaging Abnormalities to Overall Neurodevelopmental Outcome. Electronic Scientific Exhibit (eSE) at the American Society of Neuroradiology (ASNR), New Orleans, Louisiana, May 31 – June 5, 2008.
22. Supsupin EP, Bonfante-Mejia EE, Sitton CW, Vea RW, Parikh N, Cacayorin ED, Hochhauser, L: Diffuse Excessive High Signal Intensity: Predicting Neurodevelopmental Outcome in the Preterm Population. Electronic Scientific Exhibit (eSE) at the American Society of Neuroradiology (ASNR), New Orleans, Louisiana, May 31 – June 5, 2008.
23. Bonfante EE, Supsupin E, Sitton CW: Location of Focal Ischemic Changes, Perfusion Abnormalities and Angiographic Findings as Predictors of the Etiology of Acute Ischemic Stroke: A Pictionary Display. Presented at the American Society of Neuroradiology (ASNR) 46th Annual Meeting, New Orleans, Louisiana, May 31-June 5, 2008.
24. Supsupin EP, Kim HJ, Sitton, CW, Bonfante EE, Criden M, Hochhauser L: Acute Traumatic Eye Injuries: Imaging and Ophthalmologic Correlation. Electronic Scientific Exhibit at the American Society of Neuroradiology (ASNR) 48th Annual Meeting, Boston, Massachusetts, May 15-20, 2010.
25. Mallery M, Supsupin E, Bonfante E, Sitton CW: Fluoroscopic-Guided Lumbar Puncture and Blood Patch: 5-year Experience in a Single Institution. Electronic Scientific Exhibit at the American Society of Neuroradiology (ASNR) 48th Annual Meeting, Boston, Massachusetts, May 15-20, 2010.
26. Supsupin E, Bonfante-Mejia E, Choi J, Sitton CW, Hochhauser L: Bilateral absence of the common carotid arteries with separate origins of the internal and external carotid arteries detected by CT angiography: case report. ASNR Annual Meeting, 6/4-9/2011, Seattle, Washington.
27. Sarraj A, Barreto AD, Albright K, Sitton CW, Choi J, Lutzker SL, Bibars W, Martin-Schild S, Saver J, Liebeskind DS, Gupta R, Grotta JC, Savitz SI. Optimizing prediction scores for poor outcome after intra-arterial therapy for anterior circulation acute ischemic stroke. Presented at the International Stroke Conference 1/31-2/03/2012, New Orleans, Louisiana.
28. Gule M, Sitton CW. Idiopathic Hypertrophic Pachymeningitis: a Challenging Imaging Diagnosis. Electronic Scientific Exhibit at the 53rd Annual Meeting of the American Society of Neuroradiology (ASNR). Chicago, IL. April 25-30, 2015.
29. Papasozomenos H, Sitton CW, Friedman E, Choi J, Riascos R. Utility of CT Guided Spinal Biopsy in Diagnosis and Management of Vertebral Osteomyelitis and Discitis. Scientific Exhibit at the 53rd Annual Meeting of the American Society of Neuroradiology (ASNR). Chicago, IL. April 25-30, 2015.
30. Papasozomenos H, Sitton CW, Papasozonenos S, Simonetta A, Supsupin E. Imaging Findings of Disseminated Bipolaris Presenting as Extra-Axial Fungal Granulomata and Intracranial Abscesses. Electronic Scientific Exhibit at the 53rd Annual Meeting of the American Society of Neuroradiology (ASNR). Chicago, IL. April 25-30, 2015.
31. Sitton CW, Supsupin E, Choi J, Friedman E, Sarraj A. A Modification of a Collaterals Scoring System for Improved stratification of Outcome in Acute Ischemic Stroke Electronic Scientific Exhibit at the 53rd Annual Meeting of the American Society of Neuroradiology (ASNR). Chicago, IL. April 25-30, 2015.
32. Riascos R, Bonfante B, Cotes C, Sitton CW, Gule-Monroe M, Papasozomenos H. Update in Subaxial Cervical Trauma; What the Clinician Needs to Know. Electronic Scientific Exhibit at the 53rd Annual Meeting of the American Society of Neuroradiology (ASNR). Chicago, IL. April 25-30, 2015.
33. Stoffey R, Sitton CW, Bhattacharjee M, Riascos R. Papillary Craniopharyngioma Presenting as a Purely Intraventricular Lesion in an Adult. Scientific Exhibit. 54rd Annual Meeting of the American Society of Neuroradiology (ASNR). Washington, May 23-25, 2016.
34. Riascos, R, Bonfante, E, Choi, J, Mora, , Sitton CW, Spence: Causes of Spinal Hemorrhage in a Level One Trauma Center, May 23-26, 2016
35. Patel R, C Sitton , Kamali A, Syed M, Arevalo O, Calle S, Bonfante E, Riascos R, Adesina O “Clinical and Imaging Correlation of Afferent and Efferent Visual Pathways Defects: A Case Based Review” Educational Exhibit presented at American Society of Neuroradiology (ASNR) annual meeting 2018 at Vancouver, Canada.
EDUCATIONAL EXHIBITS:
1. Sitton, CW : Pre and Postnatal MRI Imaging Appearance of Intrauterine Myelomeningocele Repair, May 23-25,2016
2. Bonfante E, Ratel, R, Katrina, Patel, R, Sitton, CW, Riascos, R, Johnston: Brain MRI findings in Chiari II Malformation: Evolving from Fetal to Neonatal, May 23-25, 2016
3. Lally J, Sitton C. Tips for Optimizing Workstation Efficiency, Beyond the Basic IT Setup. 56th Annual American Society of Neuroradiology (ASNR) Vancouver BC, Canada June 2-7, 2018.