Publications

Dr. An and his group has been corresponding-authored, first-authored, and co-authored over 50 papers in prestigious journals, including Nature Metabolism, J Hepatology, eLife, Diabetes, Science, Cell Metabolism, STAR Protocols, etc. Their papers have received more than 3,600 citations with an H-index of 32 (Google Scholar).

Complete List of Published Work in My Bibliography: https://www.ncbi.nlm.nih.gov/myncbi/yu.an.1/bibliography/public/

 

Featured Articles

2024

Wang F, Huynh PM, An YA. Protocol for Seahorse analysis of ex vivo mouse brown and white adipose tissues. STAR Protoc. 2024 Jun 7;5(2):103042. doi: 10.1016/j.xpro.2024.103042. [Epub ahead of print] PubMed PMID: 38850537.

Yang Y, Xu L, Atkins C, Kuhlman L, Zhao J, Jeong JM, Wen Y, Moreno N, Kim KH, An YA, Wang F, Bynon S, Villani V, Gao B, Brombacher F, Harris R, Eltzschig HK, Jacobsen E, Ju C. Novel IL-4/HB-EGF-dependent crosstalk between eosinophils and macrophages controls liver regeneration after ischaemia and reperfusion injury. Gut. 2024 May 9;. doi: 10.1136/gutjnl-2024-332033. [Epub ahead of print] PubMed PMID: 38724220.

An YA. Recent advances in diabetic retinopathy onset in glucose-well-controlled patients: From biomarker to treatment. Sci Bull (Beijing). 2024 Apr 4;. doi: 10.1016/j.scib.2024.04.008. [Epub ahead of print] PubMed PMID: 38637229.

 

2023

Sun XN, An YA, Paschoal VA, de Souza CO, Wang MY, Vishvanath L, Bueno LM, Cobb AS, Nieto Carrion JA, Ibe ME, Li C, Kidd HA, Chen S, Li W, Gupta RK, Oh DY. GPR84-mediated signal transduction affects metabolic function by promoting brown adipocyte activity. J Clin Invest. 2023 Dec 15;133(24). doi: 10.1172/JCI168992. PubMed PMID: 37856216; PubMed Central PMCID: PMC10721148.

Onodera T, Wang MY, Rutkowski JM, Deja S, Chen S, Balzer MS, Kim DS, Sun X, An YA, Field BC, Lee C, Matsuo EI, Mizerska M, Sanjana I, Fujiwara N, Kusminski CM, Gordillo R, Gautron L, Marciano DK, Hu MC, Burgess SC, Susztak K, Moe OW, Scherer PE. Endogenous renal adiponectin drives gluconeogenesis through enhancing pyruvate and fatty acid utilization. Nat Commun. 2023 Oct 17;14(1):6531. doi: 10.1038/s41467-023-42188-4. PubMed PMID: 37848446; PubMed Central PMCID: PMC10582045.

Su W, Chi Y, An YA. Editorial: Lipid droplets and mitochondria in metabolic diseases. Front Physiol. 2023;14:1266356. doi: 10.3389/fphys.2023.1266356. eCollection 2023. PubMed PMID: 37637148; PubMed Central PMCID: PMC10455923.

Heo MJ, Suh JH, Lee SH, Poulsen KL, An YA, Moorthy B, Hartig SM, Moore DD, Kim KH. Aryl hydrocarbon receptor maintains hepatic mitochondrial homeostasis in mice. Mol Metab. 2023 Jun;72:101717. doi: 10.1016/j.molmet.2023.101717. Epub 2023 Mar 31. PubMed PMID: 37004989; PubMed Central PMCID: PMC10106517.

An YA, Xiong W, Chen S, Bu D, Rutkowski JM, Berger JP, Kusminski CM, Zhang N, An Z, Scherer PE. Endotrophin neutralization through targeted antibody treatment protects from renal fibrosis in a podocyte ablation model. Mol Metab. 2023 Mar;69:101680. doi: 10.1016/j.molmet.2023.101680. Epub 2023 Jan 22. PubMed PMID: 36696925; PubMed Central PMCID: PMC9918787.

 

2022

Zhu Y, Li N, Huang M, Chen X, An YA, Li J, Zhao S, Funcke JB, Cao J, He Z, Zhu Q, Zhang Z, Wang ZV, Xu L, Williams KW, Li C, Grove K, Scherer PE. Activating Connexin43 gap junctions primes adipose tissue for therapeutic intervention. Acta Pharm Sin B. 2022 Jul;12(7):3063-3072. doi: 10.1016/j.apsb.2022.02.020. Epub 2022 Feb 26. PubMed PMID: 35865093; PubMed Central PMCID: PMC9293664.

Frankl JA, An YA, Sherwood A, Hao G, Huang FY, Thapa P, Clegg DJ, Sun X, Scherer PE, Öz OK. Comparison of BMIPP-SPECT/CT to (18)FDG-PET/CT for Imaging Brown or Browning Fat in a Preclinical Model. Int J Mol Sci. 2022 Apr 28;23(9). doi: 10.3390/ijms23094880. PubMed PMID: 35563272; PubMed Central PMCID: PMC9101718.

Zhu Q*, An YA*, Scherer PE. Mitochondrial regulation and white adipose tissue homeostasis. Trends Cell Biol. 2022 Apr;32(4):351-364. doi: 10.1016/j.tcb.2021.10.008. Epub 2021 Nov 19. Review. PubMed PMID: 34810062; PubMed Central PMCID: PMC8918005. (*contribute equally)

 

2021 and before

Crewe C, Funcke JB, Li S, Joffin N, Gliniak CM, Ghaben AL, An YA, Sadek HA, Gordillo R, Akgul Y, Chen S, Samovski D, Fischer-Posovszky P, Kusminski CM, Klein S, Scherer PE. Extracellular vesicle-based interorgan transport of mitochondria from energetically stressed adipocytes. Cell Metab. 2021 Sep 7;33(9):1853-1868.e11. doi: 10.1016/j.cmet.2021.08.002. Epub 2021 Aug 20. PubMed PMID: 34418352; PubMed Central PMCID: PMC8429176.

An YA, Chen S, Deng Y, Wang ZV, Funcke JB, Shah M, Shan B, Gordillo R, Yoshino J, Klein S, Kusminski CM, Scherer PE. The mitochondrial dicarboxylate carrier prevents hepatic lipotoxicity by inhibiting white adipocyte lipolysis. J Hepatol. 2021 Aug;75(2):387-399. doi: 10.1016/j.jhep.2021.03.006. Epub 2021 Mar 18. PubMed PMID: 33746082; PubMed Central PMCID: PMC8292187.

An YA, Scherer PE. Mouse Adipose Tissue Protein Extraction. Bio Protoc. 2020 Jun 5;10(11):e3631. doi: 10.21769/BioProtoc.3631. eCollection 2020 Jun 5. PubMed PMID: 33659303; PubMed Central PMCID: PMC7842653.

An YA, Crewe C, Asterholm IW, Sun K, Chen S, Zhang F, Shao M, Funcke JB, Zhang Z, Straub L, Yoshino J, Klein S, Kusminski CM, Scherer PE. Dysregulation of Amyloid Precursor Protein Impairs Adipose Tissue Mitochondrial Function and Promotes Obesity. Nat Metab. 2019 Dec;1(12):1243-1257. doi: 10.1038/s42255-019-0149-1. Epub 2019 Dec 13. PubMed PMID: 31984308; PubMed Central PMCID: PMC6980705.

Park J*, Kim M*, Sun K*, An YA*, Gu X, Scherer PE. VEGF-A-Expressing Adipose Tissue Shows Rapid Beiging and Enhanced Survival After Transplantation and Confers IL-4-Independent Metabolic Improvements. Diabetes. 2017 Jun;66(6):1479-1490. doi: 10.2337/db16-1081. Epub 2017 Mar 2. PubMed PMID: 28254844; PubMed Central PMCID: PMC5440018. (*contribute equally)

An YA, Sun K, Joffin N, Zhang F, Deng Y, Donzé O, Kusminski CM, Scherer PE. Angiopoietin-2 in white adipose tissue improves metabolic homeostasis through enhanced angiogenesis. Elife. 2017 Mar 29;6. doi: 10.7554/eLife.24071. PubMed PMID: 28355132; PubMed Central PMCID: PMC5391203.

Deng Y, Wang ZV, Gordillo R, An YA, Zhang C, Liang Q, Yoshino J, Cautivo KM, De Brabander J, Elmquist JK, Horton JD, Hill JA, Klein S, Scherer PE. An adipo-biliary-uridine axis that regulates energy homeostasis. Science. 2017 Mar 17;355(6330). doi: 10.1126/science.aaf5375. Epub 2017 Mar 16. PubMed PMID: 28302796; PubMed Central PMCID: PMC5832364.