Medical Innovations Scholarly Concentration

Mission:

The Medical Innovations Scholarly Concentration (MISC) aims to foster a culture of innovation at UTHealth McGovern Medical School (MMS) by providing medical students with structured, hands-on experience in healthcare technology, medical entrepreneurship, and interdisciplinary collaboration. Through a guided framework, students will gain exposure to design thinking, regulatory pathways, commercialization strategies, and applied medical research, driving both personal growth and UTHealth Houston’s reputation as a leader in healthcare innovation.

Program Co-Directors:

Sunil Krishnan MD      Professor of Radiation Oncology

John Seymour PhD      Associate Professor of Neurosurgery

Faculty Mentors + Innovation Focus Areas

Below is a table of potential mentors and their areas of expertise:

Potential UTH MentorProfessional TitleCategory
Nitin Tandon MDProfessor of NeurosurgeryDevices: Neuroregeneration
John Seymour PhDAssociate Professor of Electrical + Computer EngineeringDevices: Neuromodulation + Diagnostics
Michael Jacobs PhDProfessor of Diagnostics + Interventional ImagingDevices: Imaging
Alireza Akhbardeh PhDAssistant Professor of Diagnostics + Interventional ImagingDevices: Imaging
Ali Azhdarinia PhDAssistant Professor of Diagnostics + Interventional ImagingDrugs: Radiopharmaceutical Imaging/Therapy
Federica Pisaneschi PhDAssistant Professor of Diagnostics + Interventional ImagingDrugs: Radiopharmaceutical Imaging/Therapy
Jagat Narula MD, PhDProfessor of Medicine (Cardiology)Drugs: Radiopharmaceutical Imaging/Therapy
Eva Sevick PhDProfessor of Molecular MedicineDrugs: Optical Imaging
John Rasmussen PhDAssistant Professor of Molecular MedicineDrugs: Optical Imaging
Daniel Harrington PhDAssistant Professor of Biomedical EngineeringDrug Delivery: Hydrogels
Sunil Krishnan MDProfessor of Radiation OncologyDrug Delivery: Nanoparticles
Zhiqiang An PhDProfessor of Molecular MedicineDrugs: Humanized Monoclonal Antibodies
Kyoji Tsuchikama PhDAssociate Professor of Pharmacology + ToxicologyDrugs: Antibody Drug Conjugates
Xin Ge PhDAssistant Professor of Pharmacology + ToxicologyDrugs: Antibody Drug Conjugates
Mikhail Kolonin PhDProfessor of Regenerative MedicineDrugs: Metabolic Disorders
Alex Gorfe PhDProfessor of Integrative Biology + PharmacologyDrugs: In Silico Modeling
Erik Wilson MDProfessor of SurgeryMinimally Invasive Surgery
Uwe Fischer MDAssociate Professor of SurgeryMinimally Invasive Surgery
Charles S. Cox Jr. MDProfessor of Pediatric SurgeryPediatric Trauma + Surgery
Nirav Thosani MDAssociate Professor of SurgeryGastrointestinal Endoscopy
Nils Johnson MDProfessor of Medicine (Cardiology)Cardiology + Coronary Physiology
David Cisek MDProfessor of Pediatric SurgeryPediatric Urology
John J. Au MDAssistant Professor of Pediatric SurgeryPediatric Urology
Olasunkanmi W. Adeyinka MDAssociate Professor of Family MedicineDigital Health + Primary Care
Julie S. Bortolotti MDClinical Assistant Professor of Family MedicineTelemedicine + Family Medicine
Sarah Cavenaugh MDAssistant Professor of PediatricsPediatric Digital Health
James Langabeer PhDProfessor of Emergency Medicine + PsychiatryHealthcare Decision Science
Bentley J. Bobrow MDProfessor of Emergency MedicineEmeregncy + Resuscitation Science
Bela Patel MDDivison Director for Pulmonary + Sleep MedicineCritical Care + Healthcare Quality
John H. Byrne PhDProfessor of NeuroscienceNeuroscience + Memory Research
Louse McCulloughProfessor of NeurologyStroke + Neurology
Vasanthi Jayaraman PhDProfessor of BiochemistryNeuropharmacology
Theresa Koehler PhDProfessor of MicrobiologyBacterial Pathogenesis
Hazim J. Safi MDProfessor of Cardiothoracic SurgeryCardiothoracic Surgery

Student Selection Criteria

  • Eligibility: Open to all McGovern MS1s in strong academic standing.
  • Application Deadline: February 28th (MS1 Spring Term)
  • Application Components:
    • Healthcare Innovation Project Proposal: Student statement of innovation interest, defined problem, proposed solution, core objectives, and expected outcomes (MS1 SRP and MS4-end)
    • Resume/Curriculum Vitae
  • Selection Process: Faculty Interview + Proposal Review.
  • Number of Accepted Students: 5 students per year

Program Deliverables + Innovation Tracks

Students must complete a research or applied innovation project leading to one of the following outcomes:

  1. Present at an Innovation Pitch Competition
  2. Publish in a Peer-Reviewed Forum or Conference Presentation
  3. Develop an Early-Stage Startup

Innovation Tracks (Recommended Categories)

  1. Surgical & Biomedical Devices: Advanced surgical tools, robotics, point-of-care testing, remote patient monitoring.
  2. Digital Health & AI: AI-driven diagnostics, telemedicine, remote patient monitoring, hospital automation.
  3. Pharmaceutical & Drug Delivery: Nanomedicine, antibody-drug conjugates, regenerative medicine.
  4. Healthcare Systems Innovation: Hospital workflow optimization, clinical decision support, patient engagement solutions.
  5. Medical Education Technology: Simulation platforms, AR/VR training, digital curriculum design, competency-based assessment tools.
  6. Mental Health Innovation: Digital mental health platforms, neurotechnology interventions, scalable community-based solutions.
  7. Health Equity & Social Determinants: Technology-enabled access to care, community health worker platforms, housing/food insecurity interventions.
  8. Infectious Diseases & Public Health: Rapid diagnostics, outbreak prediction tools, vaccination delivery systems, population-level health surveillance.
  9. Global & Low-Cost Innovation: Affordable medical devices, frugal telemedicine platforms, scalable solutions for resource-limited settings.
  10. Genomics & Precision Medicine: Genomic diagnostics, pharmacogenomics, CRISPR-based therapeutics, personalized treatment algorithms.
  11. Preventive & Lifestyle Medicine Innovation: Digital nutrition tools, wearable-based fitness and sleep tracking, culinary medicine interventions, behavioral health optimization.

Innovation Competencies

Upon completion, students will:

1. Strengthen Innovation & Problem-Solving Skills: Identify unmet healthcare needs, apply design thinking, and develop prototype-driven solutions.
2. Build Solution Design & Translation Skills: Refine concepts through testing, stakeholder feedback, and patient-centered design.
3. Gain Regulatory & Entrepreneurship Knowledge: Understand FDA approval pathways, reimbursement, intellectual property, and business strategies for implementation.
4. Sharpen Interdisciplinary Innovation Skills: Collaborate effectively across medicine, engineering, and business while developing leadership to drive healthcare change.

Medical Innovations Scholarly Concentration: Timeline & Requirements

MS1: Exploration + Orientation

Required:

  • Submit MISC Application (deadline: February 28th)
  • Submit Healthcare Innovation Project Proposal (problem, proposed solution, objectives, expected outcomes)
  • Attend Scholarly Concentration Orientation + TMC Innovation Factory Tour.
  • Attend 1 Innovation or Biodesign Workshops/Lecture (e.g., MISC Innovation Education Series, TMCi Biodesign Workshops, Rice BME, EnMed, UTHealth Center for Digital Health Innovation)
  • Innovation Project: Mentor Check-In(s)

MS1-MS2 (Summer): Foundation + Innovation Design

Required:

  • Present Project at McGovern Summer Research Program
  • Attend 1 Innovation or Biodesign Workshops/Lecture (e.g., MISC
  • Innovation Education Series, TMCi Biodesign Workshops, Rice BME,
  • EnMed, UTHealth Center for Digital Health Innovation)
  • Initiate Prototyping Development + Early Testing (if applicable)
  • Innovation Project: Mentor Check-In(s)

MS2: Prototype Development + Early Execution

Required:

  • Continue Product Development + Data Collection (refine prototype, collect data + feedback from initial test runs)
  • Attend 1 Innovation or Biodesign Workshops/Lectures (e.g., MISC Innovation Education Series, TMCi Biodesign Workshops, Rice BME, EnMed, UTHealth Center for Digital Health Innovation)
  • Innovation Project: Mentor Check-In(s)
  • Midpoint Review: Present project update to UTH Faculty Mentor(s) (MS2-end)

MS3: Prototype Refinement + Validation (Clerkship Flex-Year)

Required:

  • No Formal Project Requirements (during core-clerkships)
  • Attend 1 Innovation or Biodesign Workshops/Lecture (e.g., MISC Innovation Education Series, TMCi Biodesign Workshops, Rice BME, EnMed, UTHealth Center for Digital Health Innovation)
  • Innovation Project: Mentor Check-In(s)

MS4: Innovation Pitch + Project Dissemination

Required:

  • Finalize Product Refinement + Clinical Validation (if applicable)
  • Submit Project Abstract to McGovern Medical Student Research Office
  • Participate in UTHealth Houston ‘Shark Tank’ Innovation Pitch Competition (Panel of UTHealth experts, potential investors, stakeholders).
  • Submit Innovation to One External Pipline (where applicable)
    • Submit Publication (submission is the requirement, not acceptance)
    • Present at Innovation Conferences/Symposiums (e.g., TMC AI Summit, UTHealth Center for Digital Health Innovation Summit, McGovern Spring Senior Research Symposium, TMCi Presentation)
    • Create Innovation-Focused Start-Up with Faculty Mentor
    • Apply for Texas Nucleate Startup Incubator
    • Enroll in TMCi’s Accelerator Program
  • Attend 2 Innovation or Biodesign Workshops/Lectures (e.g., MISC  Innovation Education Series, TMCi Biodesign Workshops, Rice BME, EnMed, UTHealth Center for Digital Health Innovation)

Post-Graduation: Explore Project Continuity Opportunities

  • No Formal Requirement
  • Student Options:
    • Continue innovation project as resident/fellow
    • Handoff project to a new student.

Medical Innovations Scholarly Concentration: Completion Requirements

To graduate with the MISC distinction, students must:

  • Attend 6 Innovation Workshops + Webinars (minimum)
  • Complete McGovern SRP Requirements
  • Submit MS4 Innovation Abstract to Medical Student Research Office
  • Present “Shark Tank” Innovation Pitch to UTHealth Innovation Faculty
  • Disseminate Innovation to 1 External Source (conference, publication,
  • incubator, start-up application)